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Found 28 result(s)
The mission of the GO Consortium is to develop a comprehensive, computational model of biological systems, ranging from the molecular to the organism level, across the multiplicity of species in the tree of life. The Gene Ontology (GO) knowledgebase is the world’s largest source of information on the functions of genes. This knowledge is both human-readable and machine-readable, and is a foundation for computational analysis of large-scale molecular biology and genetics experiments in biomedical research.
Reactome is a manually curated, peer-reviewed pathway database, annotated by expert biologists and cross-referenced to bioinformatics databases. Its aim is to share information in the visual representations of biological pathways in a computationally accessible format. Pathway annotations are authored by expert biologists, in collaboration with Reactome editorial staff and cross-referenced to many bioinformatics databases. These include NCBI Gene, Ensembl and UniProt databases, the UCSC and HapMap Genome Browsers, the KEGG Compound and ChEBI small molecule databases, PubMed, and Gene Ontology.
Our knowledge of the many life-forms on Earth - of animals, plants, fungi, protists and bacteria - is scattered around the world in books, journals, databases, websites, specimen collections, and in the minds of people everywhere. Imagine what it would mean if this information could be gathered together and made available to everyone – anywhere – at a moment’s notice. This dream is becoming a reality through the Encyclopedia of Life.
CorrDB has data of cattle, relating to meat production, milk production, growth, health, and others. This database is designed to collect all published livestock genetic/phenotypic trait correlation data, aimed at facilitating genetic network analysis or systems biology studies.
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iDog, an integrated resource for domestic dog (Canis lupus familiaris) and wild canids, provides the worldwide dog research community a variety of data services. This includes Genes, Genomes, SNPs, Breed/Disease Traits, Gene Expressions, Single Cell, Dog-Human Homolog Diseases and Literatures. In addition, iDog provides Online tools for performing genomic data visualization and analyses.
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Morph·D·Base has been developed to serve scientific research and education. It provides a platform for storing the detailed documentation of all material, methods, procedures, and concepts applied, together with the specific parameters, values, techniques, and instruments used during morphological data production. In other words, it's purpose is to provide a publicly available resource for recording and documenting morphological metadata. Moreover, it is also a repository for different types of media files that can be uploaded in order to serve as support and empirical substantiation of the results of morphological investigations. Our long-term perspective with Morph·D·Base is to provide an instrument that will enable a highly formalized and standardized way of generating morphological descriptions using a morphological ontology that will be based on the web ontology language (OWL - http://www.w3.org/TR/owl-features/). This, however, represents a project that is still in development.
E-RA provides a permanent managed repository and knowledgebase for secure storage of metadata and data from Rothamsted's Long-term Experiments, the oldest, continuous agronomic experiments in the world. Together with the accompanying meteorological records, associated documentation and sample archive, it is a unique historical record of experiments that have been measured continuously since 1843. e-RA provides comprehensive descriptions of Rothamsted's long-term experiments including Broadbalk Wheat, Park Grass Hay, Hoosfield Barley, Rothamsted and Woburn Ley Arables, and Long-term Liming. e-RA maintains long-term routine data collections including crop yields, quality traits, agronomic management, soil chemistry, disease, and botanical diversity. The experiments are available as a research infrastructure to scientists and scientists are encouraged to deposit any new data generated with e-RA.
Merritt is a curation repository for the preservation of and access to the digital research data of the ten campus University of California system and external project collaborators. Merritt is supported by the University of California Curation Center (UC3) at the California Digital Library (CDL). While Merritt itself is content agnostic, accepting digital content regardless of domain, format, or structure, it is being used for management of research data, and it forms the basis for a number of domain-specific repositories, such as the ONEShare repository for earth and environmental science and the DataShare repository for life sciences. Merritt provides persistent identifiers, storage replication, fixity audit, complete version history, REST API, a comprehensive metadata catalog for discovery, ATOM-based syndication, and curatorially-defined collections, access control rules, and data use agreements (DUAs). Merritt content upload and download may each be curatorially-designated as public or restricted. Merritt DOIs are provided by UC3's EZID service, which is integrated with DataCite. All DOIs and associated metadata are automatically registered with DataCite and are harvested by Ex Libris PRIMO and Thomson Reuters Data Citation Index (DCI) for high-level discovery. Merritt is also a member node in the DataONE network; curatorially-designated data submitted to Merritt are automatically registered with DataONE for additional replication and federated discovery through the ONEMercury search/browse interface.
ANPERSANA is the digital library of IKER (UMR 5478), a research centre specialized in Basque language and texts. The online library platform receives and disseminates primary sources of data issued from research in Basque language and culture. As of today, two corpora of documents have been published. The first one, is a collection of private letters written in an 18th century variety of Basque, documented in and transcribed to modern standard Basque. The discovery of the collection, named Le Dauphin, has enabled the emerging of new questions about the history and sociology of writing in the domain of minority languages, not only in France, but also among the whole Atlantic Arc. The second of the two corpora is a selection of sound recordings about monodic chant in the Basque Country. The documents were collected as part of a PhD thesis research work that took place between 2003 and 2012. It's a total of 50 hours of interviews with francophone and bascophone cultural representatives carried out at either their workplace of the informers or in public areas. ANPERSANA is bundled with an advanced search engine. The documents have been indexed and geo-localized on an interactive map. The platform is engaged with open access and all the resources can be uploaded freely under the different Creative Commons (CC) licenses.
The Biological and Chemical Oceanography Data Management Office (BCO-DMO) is a publicly accessible earth science data repository created to curate, publicly serve (publish), and archive digital data and information from biological, chemical and biogeochemical research conducted in coastal, marine, great lakes and laboratory environments. The BCO-DMO repository works closely with investigators funded through the NSF OCE Division’s Biological and Chemical Sections and the Division of Polar Programs Antarctic Organisms & Ecosystems. The office provides services that span the full data life cycle, from data management planning support and DOI creation, to archive with appropriate national facilities.
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The Mediterranean Germplasm Database (MGD) is the digital twin of the agri-food plant seed collection (Mediterranean Germplasm Genebank - MGG) maintained at the Institute of Biosciences and BioResources (IBBR) of the Italian National Research Council (CNR) in Bari, Italy. Overall, the collection preserves more than 59,000 accessions of 870 species from 203 genera and 39 families (mainly Poaceae, Fabaceae, Solanaceae, Brassicaceae, Asteraceae, etc.). Over 13,000 samples have been directly collected through time and georeferenced by IBBR exploration teams, while others have been acquired from other Institutions through exchange activities. The main objective of MGG is the preservation of genetic resources of herbaceous plants of interest for the Mediterranean agriculture. Particular attention is dedicated to specific segments of plant genetic resources, such as local varieties (including "typical products") or endangered agro-ecotypes, wild relatives of crops and plants potentially useful for the extraction of bioactive or biotechnological compounds. The main commitments of MGG since 1970 are: (i) the collection, conservation and distribution of PGR; (ii) the characterization and evaluation of PGRs and the analysis of their genetic structure; (ii) the selection and pre-breeding of PGR, and the recognition of useful genes.
GeneWeaver combines cross-species data and gene entity integration, scalable hierarchical analysis of user data with a community-built and curated data archive of gene sets and gene networks, and tools for data driven comparison of user-defined biological, behavioral and disease concepts. Gene Weaver allows users to integrate gene sets across species, tissue and experimental platform. It differs from conventional gene set over-representation analysis tools in that it allows users to evaluate intersections among all combinations of a collection of gene sets, including, but not limited to annotations to controlled vocabularies. There are numerous applications of this approach. Sets can be stored, shared and compared privately, among user defined groups of investigators, and across all users.
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MDM-Portal (Medical Data Models) is a meta-data registry for creating, analyzing, sharing and reusing medical forms. It serves as an infrastructure for academic (non-commercial) medical research to contribute a solution to this problem. It contains forms in the system-independent CDISC Operational Data Model (ODM) format with more than 500,000 data-elements. The Portal provides numerous core data sets, common data elements or data standards, code lists and value sets. This enables researchers to view, discuss, download and export forms in most common technical formats such as PDF, CSV, Excel, SQL, SPSS, R, etc.
BrainMaps.org, launched in May 2005, is an interactive multiresolution next-generation brain atlas that is based on over 20 million megapixels of sub-micron resolution, annotated, scanned images of serial sections of both primate and non-primate brains and that is integrated with a high-speed database for querying and retrieving data about brain structure and function over the internet. Currently featured are complete brain atlas datasets for various species, including Macaca mulatta, Chlorocebus aethiops, Felis catus, Mus musculus, Rattus norvegicus, and Tyto alba.
The Evidence-based Practice Center (EPC) at Tufts Medical Center, with support from the Agency for Healthcare Research and Quality (AHRQ), has developed the Systematic Review Data Repository (SRDR), which is a Web-based tool for data extraction and storage of systematic review data. Potential users include patients, policy makers/stakeholders, independent researchers, research centers, and funders of research.
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The Italian Archive of Historical Earthquake Data ASMI (Archivio Storico Macrosismico Italiano) provides access to data on more than 6500 Italian earthquakes in the period 461 b.C to 2020, deriving from more than 430 seismological studies. For each earthquake, different kinds of studies are accessible, giving a wide perspective on the multiplicity of the available information.
KiMoSys, a web application for quantitative KInetic MOdels of biological SYStems. Kinetic models, with the aim to understand and subsequently design the metabolism of organism of interest are constructed iteratively and require accurate experimental data for both the generation and verification of hypotheses. Therefore, there is a growing requirement for exchanging experimental data and models between the systems biology community, and to automate as much as possible the kinetic model building, editing, simulation and analysis steps.
The Human Ageing Genomic Resources (HAGR) is a collection of databases and tools designed to help researchers study the genetics of human ageing using modern approaches such as functional genomics, network analyses, systems biology and evolutionary analyses.
4DGenome is a public database that archives and disseminates chromatin interaction data. Currently, 4DGenome contains over 8,038,247 interactions curated from both experimental studies (high throughput and individual studies) and computational predictions. It covers five organisms, Homo sapiens, Mus musculus, Drosophila melanogaster, Plasmodium falciparum, and Saccharomyces cerevisiae.
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BioMemory is the network of biological collections of the Department of Biology, Agriculture and Food Sciences (DiSBA) of the National Research Council of Italy (CNR) for bio-monitoring, biodiversity conservation, agri-food and environmental sustainability, and human well-being. The project is aimed to create a network of biobanks (i.e., scientific research collections) where data and metadata associated to biological samples of different nature are collected and stored in a systematic and well-organized way. Maintaining the existing collections will allow their future use for a number of purposes, from the genetic improvement of organisms to face environmental changes (climate-ready organisms) to the fight against epidemics and pandemics affecting humans, animals and plants.
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ALEXA is a microarray design platform for 'alternative expression analysis'. This platform facilitates the design of expression arrays for analysis of mRNA isoforms generated from a single locus by the use of alternative transcription initiation, splicing and polyadenylation sites. We use the term 'ALEXA' to describe a collection of novel genomic methods for 'alternative expression' analysis. 'Alternative expression' refers to the identification and quantification of alternative mRNA transcripts produced by alternative transcript initiation, alternative splicing and alternative polyadenylation. This website provides supplementary materials, source code and other downloads for recent publications describing our studies of alternative expression (AE). Most recently we have developed a method, 'ALEXA-Seq' and associated resources for alternative expression analysis by massively parallel RNA sequencing.
SwissLipids is an expert curated resource that provides a framework for the integration of lipid and lipidomic data with biological knowledge and models.