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Found 67 result(s)
The HUGO Gene Nomenclature Committee (HGNC) assigned unique gene symbols and names to over 35,000 human loci, of which around 19,000 are protein coding. This curated online repository of HGNC-approved gene nomenclature and associated resources includes links to genomic, proteomic and phenotypic information, as well as dedicated gene family pages.
The European Bioinformatics Institute (EBI) has a long-standing mission to collect, organise and make available databases for biomolecular science. It makes available a collection of databases along with tools to search, download and analyse their content. These databases include DNA and protein sequences and structures, genome annotation, gene expression information, molecular interactions and pathways. Connected to these are linking and descriptive data resources such as protein motifs, ontologies and many others. In many of these efforts, the EBI is a European node in global data-sharing agreements involving, for example, the USA and Japan.
The IMEx consortium is an international collaboration between a group of major public interaction data providers who have agreed to share curation effort and develop and work to a single set of curation rules when capturing data from both directly deposited interaction data or from publications in peer-reviewed journals, capture full details of an interaction in a “deep” curation model, perform a complete curation of all protein-protein interactions experimentally demonstrated within a publication, make these interaction available in a single search interface on a common website, provide the data in standards compliant download formats, make all IMEx records freely accessible under the Creative Commons Attribution License
<<<!!!<<< Phasing out support for the Database of Genomic Variants archive (DGVa). The submission, archiving, and presentation of structural variation services offered by the DGVa is transitioning to the European Variation Archive (EVA) https://www.re3data.org/repository/r3d100011553. All of the data shown in the DGVa website is already searchable and browsable from the EVA Study Browser. Submission of structural variation data to EVA is done using the VCF format. The VCF specification allows representing multiple types of structural variants such as insertions, deletions, duplications and copy-number variants. Other features such as symbolic alleles, breakends, confidence intervals etc., support more complex events, such as translocations at an imprecise position. >>>!!!>>>
The Infrared Space Observatory (ISO) is designed to provide detailed infrared properties of selected Galactic and extragalactic sources. The sensitivity of the telescopic system is about one thousand times superior to that of the Infrared Astronomical Satellite (IRAS), since the ISO telescope enables integration of infrared flux from a source for several hours. Density waves in the interstellar medium, its role in star formation, the giant planets, asteroids, and comets of the solar system are among the objects of investigation. ISO was operated as an observatory with the majority of its observing time being distributed to the general astronomical community. One of the consequences of this is that the data set is not homogeneous, as would be expected from a survey. The observational data underwent sophisticated data processing, including validation and accuracy analysis. In total, the ISO Data Archive contains about 30,000 standard observations, 120,000 parallel, serendipity and calibration observations and 17,000 engineering measurements. In addition to the observational data products, the archive also contains satellite data, documentation, data of historic aspects and externally derived products, for a total of more than 400 GBytes stored on magnetic disks. The ISO Data Archive is constantly being improved both in contents and functionality throughout the Active Archive Phase, ending in December 2006.
SOHO, the Solar & Heliospheric Observatory, is a project of international collaboration between ESA and NASA to study the Sun from its deep core to the outer corona and the solar wind. SOHO was launched on December 2, 1995. The SOHO spacecraft was built in Europe by an industry team led by prime contractor Matra Marconi Space (now EADS Astrium) under overall management by ESA. The twelve instruments on board SOHO were provided by European and American scientists.
Copernicus is a European system for monitoring the Earth. Copernicus consists of a complex set of systems which collect data from multiple sources: earth observation satellites and in situ sensors such as ground stations, airborne and sea-borne sensors. It processes these data and provides users with reliable and up-to-date information through a set of services related to environmental and security issues. The services address six thematic areas: land monitoring, marine monitoring, atmosphere monitoring, climate change, emergency management and security. The main users of Copernicus services are policymakers and public authorities who need the information to develop environmental legislation and policies or to take critical decisions in the event of an emergency, such as a natural disaster or a humanitarian crisis. Based on the Copernicus services and on the data collected through the Sentinels and the contributing missions , many value-added services can be tailored to specific public or commercial needs, resulting in new business opportunities. In fact, several economic studies have already demonstrated a huge potential for job creation, innovation and growth.
MGnify (formerly: EBI Metagenomics) offers an automated pipeline for the analysis and archiving of microbiome data to help determine the taxonomic diversity and functional & metabolic potential of environmental samples. Users can submit their own data for analysis or freely browse all of the analysed public datasets held within the repository. In addition, users can request analysis of any appropriate dataset within the European Nucleotide Archive (ENA). User-submitted or ENA-derived datasets can also be assembled on request, prior to analysis.
The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.
IntAct provides a freely available, open source database system and analysis tools for molecular interaction data. All interactions are derived from literature curation or direct user submissions and are freely available.
This is a database for vegetation data from West Africa, i.e. phytosociological and dendrometric relevés as well as floristic inventories. The West African Vegetation Database has been developed in the framework of the projects “SUN - Sustainable Use of Natural Vegetation in West Africa” and “Biodiversity Transect Analysis in Africa” (BIOTA, https://www.biota-africa.org/).
The Database of Protein Disorder (DisProt) is a curated database that provides information about proteins that lack fixed 3D structure in their putatively native states, either in their entirety or in part. DisProt is a community resource annotating protein sequences for intrinsically disorder regions from the literature. It classifies intrinsic disorder based on experimental methods and three ontologies for molecular function, transition and binding partner.
MatrixDB is a freely available database focused on interactions established by extracellular proteins and polysaccharides. MatrixDB takes into account the multimetric nature of the extracellular proteins (e.g. collagens, laminins and thrombospondins are multimers). MatrixDB includes interaction data extracted from the literature by manual curation in our lab, and offers access to relevant data involving extracellular proteins provided by our IMEx partner databases through the PSICQUIC webservice, as well as data from the Human Protein Reference Database. MatrixDB is in charge of the curation of papers published in Matrix Biology since January 2009
EnsemblPlants is a genome-centric portal for plant species. Ensembl Plants is developed in coordination with other plant genomics and bioinformatics groups via the EBI's role in the transPLANT consortium.
Public Opinion in the European Union. Our surveys address major topics concerning European citizenship. The Standard Eurobarometer was established in 1973. Since 1973, the European Commission has been monitoring the evolution of public opinion in the Member States, thus helping the preparation of texts, decision-making and the evaluation of its work. Our surveys and studies address major topics concerning European citizenship: enlargement, social situation, health, culture, information technology, environment, the Euro, defence, etc. Each survey consists of approximately 1000 face-to-face interviews per country. Reports are published twice yearly. Reproduction is authorised, except for commercial purposes, provided the source is acknowledged. Special Eurobarometer reports are based on in-depth thematic studies carried out for various services of the European Commission or other EU Institutions and integrated in the Standard Eurobarometer's polling waves. Reproduction is authorised, except for commercial purposes, provided the source is acknowledged. Flash Eurobarometers are ad hoc thematic telephone interviews conducted at the request of any service of the European Commission. Flash surveys enable the Commission to obtain results relatively quickly and to focus on specific target groups, as and when required. Reproduction is authorised, except for commercial purposes, provided the source is acknowledged. The qualitative studies investigate in-depth the motivations, feelings and reactions of selected social groups towards a given subject or concept, by listening to and analysing their way of expressing themselves in discussion groups or with non-directive interviews.
The ACTRIS DC is designed to assist scientists with discovering and accessing atmospheric data and contains an up-to-date catalogue of available datasets in a number of databases distributed throughout the world. A site like this can never be complete, but we have aimed at including datasets from the most relevant databases to the ACTRIS project, also building on the work and experiences achieved in the EU FP6 research project Global Earth Observation and Monitoring. The focus of the web portal is validated data, but it is also possible to browse the ACTRIS data server for preliminary data (rapid delivery data) through this site. The web site allows you to search in a local metadata catalogue that contains information on actual datasets that are archived in external archives. It is set up so that you can search for data by selecting the chemical/physical variable, the data location, the database that holds the data, the type of data, the data acquisition platform, and the data matrix
The EPN (or EUREF Permanent Network) is a voluntary organization of several European agencies and universities that pool resources and permanent GNSS station data to generate precise GNSS products. The EPN has been created under the umbrella of the International Association Geodesy and more precisely by its sub-commission EUREF. The European Terrestrial Reference System 89 (ETRS89) is used as the standard precise GPS coordinate system throughout Europe. Supported by EuroGeographics and endorsed by the EU, this reference system forms the backbone for all geographic and geodynamic projects on the European territory both on a national as on an international level.
mentha archives evidence collected from different sources and presents these data in a complete and comprehensive way. Its data comes from manually curated protein-protein interaction databases that have adhered to the IMEx consortium. The aggregated data forms an interactome which includes many organisms. mentha is a resource that offers a series of tools to analyse selected proteins in the context of a network of interactions. Protein interaction databases archive protein-protein interaction (PPI) information from published articles. However, no database alone has sufficient literature coverage to offer a complete resource to investigate "the interactome". mentha's approach generates every week a consistent interactome (graph). Most importantly, the procedure assigns to each interaction a reliability score that takes into account all the supporting evidence. mentha offers eight interactomes (Homo sapiens, Arabidopsis thaliana, Caenorhabditis elegans, Drosophila melanogaster, Escherichia coli K12, Mus musculus, Rattus norvegicus, Saccharomyces cerevisiae) plus a global network that comprises every organism, including those not mentioned. The website and the graphical application are designed to make the data stored in mentha accessible and analysable to all users. Source databases are: MINT, IntAct, DIP, MatrixDB and BioGRID.
The Cellular Phenotype database stores data derived from high-throughput phenotypic studies and it is being developed as part of the Systems Microscopy Network of Excellence project. The aim of the Cellular Phenotype database is to provide easy access to phenotypic data and facilitate the integration of independent phenotypic studies. Through its interface, users can search for a gene of interest, or a collection of genes, and retrieve the loss-of-function phenotypes observed, in human cells, by suppressing the expression of the selected gene(s), through RNA interference (RNAi), across independent phenotypic studies. Similarly, users can search for a phenotype of interest and retrieve the RNAi reagents that have caused such phenotype and the associated target genes. Information about specific RNAi reagents can also be obtained when searching for a reagent ID.
As part of the Copernicus Space Component programme, ESA manages the coordinated access to the data procured from the various Contributing Missions and the Sentinels, in response to the Copernicus users requirements. The Data Access Portfolio documents the data offer and the access rights per user category. The CSCDA portal is the access point to all data, including Sentinel missions, for Copernicus Core Users as defined in the EU Copernicus Programme Regulation (e.g. Copernicus Services).The Copernicus Space Component (CSC) Data Access system is the interface for accessing the Earth Observation products from the Copernicus Space Component. The system overall space capacity relies on several EO missions contributing to Copernicus, and it is continuously evolving, with new missions becoming available along time and others ending and/or being replaced.