Repository details

International Mouse Phenotyping Consortium

Name of repository
International Mouse Phenotyping Consortium
Additional name(s)
  • IMPC
  • The International Knockout Mouse Consortium
  • IKMC
  • Intgernational Mouse Phenotyping Consortium
Repository URL
https://www.mousephenotype.org/
Subject(s)
Description
The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.
Contact(s)
Keyword(s)
Persistent identifier(s) of the repository
Repository size
9.073 phenotyped genes; 9.774 phenotyped mutant lines; 111.485 phenotype calls;
Repository type(s)
  • disciplinary
Mission statement for designated community
https://www.mousephenotype.org/about-impc/
Research data repository language(s)
  • English
Data and/or service provider
  • dataProvider

Institutions (16)

Institution
Australian Phenomics Network
Additional name(s)
  • APN
Institution
Country
Australia
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
Baylor College of Medicine
Institution
Country
United States
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
Consiglio Nazionale delle Ricerche 'A. Buzzati-Traverso' Campus, Monterondo
Additional name(s)
  • CNR Monterotondo
  • EMMA (European Mouse Mutant Archive)
Country
Italy
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
European Molecular Biology Laboratory, European Bioinformatics Institute
Additional name(s)
  • EMBL-EBI
Institution
Country
European Union
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt
Additional name(s)
  • Helmholtz Zentrum München
  • HMGU
Institution
Country
Germany
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
Institut Clinique de la Souris
Additional name(s)
  • ICS
Institution
Country
France
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
International Mouse Phenotyping Consortium
Additional name(s)
  • IMPC
Institution
Country
International
Type(s) of responsibility
  • general
  • technical
Type of institution
non-profit
Institution
Mary Lyon Centre at MRC Harwell
Additional name(s)
  • MRC Mouse Network
  • Medical Research Council Harwell
Institution
Country
United Kingdom
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
Nanjing University
Additional name(s)
  • Model Animal Research Center of Nanjing University
  • MARC Nanjing University
Institution
Country
China
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
National Laboratory Animal Center, National Applied Research Laboratories
Additional name(s)
  • NLAC, NARLabs
Institution
Country
Taiwan
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
RIKEN BioResource Center
Additional name(s)
  • RIKEN BRC
Institution
Country
Japan
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
Seoul National University, College of Veterinary Medicine, Lab of Developmental Biology and Genomics
Country
Korea, Republic of
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
The Centre for Phenogenomics
Additional name(s)
  • TCP
Institution
Country
Canada
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
The Davis, Toronto, Charles River and CHORI Consortium (DTCC)
Additional name(s)
  • DTCC Consortium
Country
Canada
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
The Jackson Laboratory
Additional name(s)
  • JAX
Institution
Country
United States
Type(s) of responsibility
  • general
Type of institution
non-profit
Institution
Wellcome Sanger Institute
Institution
Country
United Kingdom
Type(s) of responsibility
  • general
Type of institution
non-profit

Policies (2)

Policy Name
Terms of Use
Policy Name
IMPC Help & Documentation

Database access

Type of access to research data repository
open

Database licenses (1)

Database License
other

Data access (1)

Type of access to data
open

Data licenses (2)

DataLicense
other
DataLicense
CC

Data upload (1)

Type of data upload
restricted
Data upload restriction type(s)
  • feeRequired
Persistent identifier system(s)
  • none
Name of the repository software
  • unknown
Versioning
yes
Data citation guideline
https://www.mousephenotype.org/help/faqs/how-do-i-cite-the-impc/
Enhanced Publication
yes
Quality management
yes
Profile(s)

Application programming interfaces (2)

Type
REST
Url
https://www.mousephenotype.org/help/programmatic-data-access/
Type
FTP
Url
ftp://ftp.ebi.ac.uk/pub/databases/impc/

Remarks

Remarks
The web services of the International Knockout Mouse (IKMC) have been transferred to the International Mouse Phenotyping Consortium (IMPC). The International Mouse Phenotyping Consortium (IMPC) Comprises a group of major mouse genetics research institutions along with national funding organisations formed to address the challenge of developing an encyclopedia of mammalian gene function. The IMPC is currently composed of 18 research institutions and 5 national funders https://www.mousephenotype.org/about-impc/consortium-members/ The IKMC includes the following programs: Knockout Mouse Project (KOMP) (USA),European Conditional Mouse Mutagenesis Program (EUCOMM) (Europe), EUCOMM: Tools for Functional Annotation of the Mouse Genome (EUCOMMTOOLS) (Europe), North American Conditional Mouse Mutagenesis Project (NorCOMM) (Canada), Texas A&M Institute for Genomic Medicine (TIGM) (USA). Institutional Members: https://www.mousephenotype.org/about-impc/consortium-members/
Entry date
2014-03-06
Last update
2024-11-21
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Cite this re3data.org record:

re3data.org: International Mouse Phenotyping Consortium; editing status 2024-11-21; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3QW4S last accessed: 2024-12-08