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Found 202 result(s)

Reactome

a curated pathway database

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Reactome is a manually curated, peer-reviewed pathway database, annotated by expert biologists and cross-referenced to bioinformatics databases. Its aim is to share information in the visual representations of biological pathways in a computationally accessible format. Pathway annotations are authored by expert biologists, in collaboration with Reactome editorial staff and cross-referenced to many bioinformatics databases. These include NCBI Gene, Ensembl and UniProt databases, the UCSC and HapMap Genome Browsers, the KEGG Compound and ChEBI small molecule databases, PubMed, and Gene Ontology.

Canadian Research Data Centre Network

CRDCN

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Research Data Centres offer a secure access to detailed microdata from Statistics Canada's surveys, and to Canadian censuses' data, as well as to an increasing number of administrative data sets. The search engine was designed to help you find out more easily which dataset among all the surveys available in the RDCs best suits your research needs.

CRYSTMET

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<<<!!!<<< The database is no longer available from 1st July 2018 >>>!!!>>> CRYSTMET was previously included in the NCDS as part of CrystalWorks. Unfortunately we are no longer able to license the CRYSTMET database for access through the NCDS. Therefore the database will no longer be accessible from 1st July 2018. >>>> CRYSTMET contains chemical, crystallographic and bibliographic data together with associated comments regarding experimental details for each study. It is a database of critically evaluated crystallographic data for metals, including alloys, intermetallics and minerals.Using these data, a number of associated files are derived, a major one being a parallel file of calculated powder patterns. These derived data are included within the CRYSTMET product.

Database of Religious History

DRH

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The DRH is a quantitative and qualitative encyclopedia of religious history. It consists of a variety of entry types including religious group and religious place. Scholars contribute entries on their area of expertise by answering questions in standardised polls. Answers are initially coded in the binary format Yes/No or categorically, with comment boxes for qualitative comments, references and links. Experts are able to answer both Yes and No to the same question, enabling nuanced answers for specific circumstances. Media, such as photos, can also be attached to either individual questions or whole entries. The DRH captures scholarly disagreement, through fine-grained records and multiple temporally and spatially overlapping entries. Users can visualise changes in answers to questions over time and the extent of scholarly consensus or disagreement.

NetPath

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<<<!!!<<< This repository is no longer available. >>>!!!>>> NetPath is currently one of the largest open-source repository of human signaling pathways that is all set to become a community standard to meet the challenges in functional genomics and systems biology. Signaling networks are the key to deciphering many of the complex networks that govern the machinery inside the cell. Several signaling molecules play an important role in disease processes that are a direct result of their altered functioning and are now recognized as potential therapeutic targets. Understanding how to restore the proper functioning of these pathways that have become deregulated in disease, is needed for accelerating biomedical research. This resource is aimed at demystifying the biological pathways and highlights the key relationships and connections between them. Apart from this, pathways provide a way of reducing the dimensionality of high throughput data, by grouping thousands of genes, proteins and metabolites at functional level into just several hundreds of pathways for an experiment. Identifying the active pathways that differ between two conditions can have more explanatory power than just a simple list of differentially expressed genes and proteins.

Agri-environmental Research Data Dataverse

University of Guelph Dataverse

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Agri-environmental Research Data collection is part of the University of Guelph Research Data Repositories (University of Guelph Dataverse). The purpose of this collection is to provide access to, and long-term stewardship of, agricultural and environmental data created at or in cooperation with the University of Guelph.

Comprehensive Antibiotic Resistance Database

CARD

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A bioinformatic database of antimicrobial resistance genes, their products and associated phenotypes.

Canadian Opinion Research Archive

CORA

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The Canadian Opinion Research Archive at Queen's University makes available commercial and independent surveys to the academic, research and journalistic communities. Founded in 1992, CORA contains hundreds of surveys including thousands of discrete items collected by major commercial Canadian firms dating back to the 1970s. CORA is continually adding new surveys and is always soliciting new data from commercial research firms, independent think tanks, research institutes, NGOs, and academic researchers. This website also includes readily accessible results from these surveys, tracking Canadian opinion over time on frequently asked survey questions, as well as tabular results from recent Canadian surveys, and more general information on polling. This material is made available as a public service by CORA and its partners.

Bedford Institute of Oceanography - Oceanographic Databases

Institut océanographique de Bedford - Bases de données océanographiques

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Databases maintained by Ocean Sciences at the Bedford Institute of Oceanography, including temperature-salinity profiles for the NW Atlantic, sea-surface temperature and chlorophyll from satellite, monthly statistics of ocean currents and other moored instruments, and daily temperature observations from coastal thermographs.

International Mouse Phenotyping Consortium

IMPC

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The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.

National Contaminants Information System

NCIS

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<<<!!!<<< 2021-03-19: The repository is no longer available >>>!!!>>> The National Contaminants Information System was begun as part of the Department's Green Plan. The NCIS is a computerized warehouse of information on toxic chemicals in fish, other aquatic life and their habitats. It was built to help manage the growing base of data and information.

UNESCO Institute for Statistics, Data Centre

UIS.stat

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A primary source for cross-nationally comparable statistics on education, science and technology, culture, and communication for more than 200 countries and territories.

C. Elegans Gene Expression

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<<<!!!<<< Genome data generated by BC Genome Sciences Centre is no longer available through this site as it is regularly deposited into controlled data repositories such as the European Genome Phenome Archive (EGA); ICGC (International Cancer Genome Consortium) and the Genome Data Commons (GDC) >>>!!!>>> Using serial analysis of gene expression (SAGE) and microarrays, we are examining total mRNA populations in all developmental stages, both in whole worms and in specific cells and tissues. In addition, we are building promoter::GFP constructs to monitor gene expression in transgenic worms, focusing on C. elegans genes that have human orthologues. Also available are web-based PCR primer design tools, and access to information about our C. elegans Fosmid library.

American Mineralogist Crystal Structure Database

AMCSD

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AMCSD is an interface to a crystal structure database that includes every structure published in the American Mineralogist, The Canadian Mineralogist, European Journal of Mineralogy and Physics and Chemistry of Minerals, as well as selected datasets from other journals. The database is maintained under the care of the Mineralogical Society of America and the Mineralogical Association of Canada, and financed by the National Science Foundation. You may search by a mineral of your choice, or choose a mineral from a complete list to help aid your research.

ChIP-Seq Transcription Factor Data

ChIP-Seq

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We developed a method, ChIP-sequencing (ChIP-seq), combining chromatin immunoprecipitation (ChIP) and massively parallel sequencing to identify mammalian DNA sequences bound by transcription factors in vivo. We used ChIP-seq to map STAT1 targets in interferon-gamma (IFN-gamma)-stimulated and unstimulated human HeLa S3 cells, and compared the method's performance to ChIP-PCR and to ChIP-chip for four chromosomes.For both Chromatin- immunoprecipation Transcription Factors and Histone modifications. Sequence files and the associated probability files are also provided.

CASRdb

Calcium Sensing Receptor Database

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<<<!!!<<< This repository is no longer available. >>>!!!>>> Message since 2018-06: This virtual host is being reconstructed.

Viral Bioinformatics Resource Center

VBRC

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Databases of viral genomic information (genes, gene families, and genomes), and software to perform comparative genomics analyses

Cystic Fibrosis Mutation Database

CFTR1

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The Cystic Fibrosis Mutation Database (CFTR1) was initiated by the Cystic Fibrosis Genetic Analysis Consortium in 1989 to increase and facilitate communications among CF researchers, and is maintained by the Cystic Fibrosis Centre at the Hospital for Sick Children in Toronto. The specific aim of the database is to provide up to date information about individual mutations in the CFTR gene. In a major upgrade in 2010, all known CFTR mutations and sequence variants have been converted to the standard nomenclature recommended by the Human Genome Variation Society.

Brain-CODE

Brain-Centre for Ontario Data Exploration

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Brain-CODE is a large-scale informatics platform that manages the acquisition and storage of multidimensional data collected from participants with a variety of brain disorders.

TopFIND

The public knowledgebase for protein termini and protease processing

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TopFIND is a protein-centric database for the annotation of protein termini currently in its third version. Non-canonical protein termini can be the result of multiple different biological processes, including pre-translational processes such as alternative splicing and alternative translation initiation or post-translational protein processing by proteases that cleave proteases as part of protein maturation or as a regulatory modification. Accordingly, protein termini evidence in TopFIND is inferred from other databases such as ENSEMBL transcripts, TISdb for alternative translation initiation, MEROPS for protein cleavage by proteases, and UniProt for canonical and protein isoform start sites.

BenchSCI

A.I. Driven Antibody Search

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BenchSci is a free platform designed to help biomedical research scientists quickly and easily identify validated antibodies from publications. Using various filters including techniques, tissue, cell lines, and more, scientists can find out published data along with the antibody that match specific experimental contexts within seconds. Free registration & access for academic research scientists.

CIS-BP

Catalog of Inferred Sequence Binding Preferences

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The Catalog of Inferred Sequence Binding Preferences (CIS-BP) is a library of transcription factor (TF) DNA binding motifs and specificities. The data are organized in a user friendly manner for ease of searching, browsing, and downloading. CIS-BP also includes built-in web tools for scanning DNA sequences for putative TF binding sites, predicting the DNA binding motif of a given TF, and identifying a TF that might recognize a given DNA motif.

IHEC Data Portal

International Human Epigenome Consortium Data Portal

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The International Human Epigenome Consortium (IHEC) makes available comprehensive sets of reference epigenomes relevant to health and disease. The IHEC Data Portal can be used to view, search and download the data already released by the different IHEC-associated projects.

Health Canada Drug Product Database

DPD

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The Health Canada Drug Product Database contains product specific information on drugs approved for use in Canada. The database is managed by Health Canada and includes human pharmaceutical and biological drugs, veterinary drugs and disinfectant products. It contains approximately 15,000 products which companies have notified Health Canada as being marketed.

Alberta Biodiversity Monitoring Institute Data & Analytics Portal

ABMI Data & Analytics Portal

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Data Download section provides easy access to the ABMI’s data and innovative data products ranging from raw field data, to species habitat associations, to remote sensing and geospatial products, to animal camera trap data, and more.