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Found 211 result(s)

Harvard Medical School, Library of Integrated Network-Based Cellular Signatures Database

HMS, LINCS database

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The Database contains all publicly available HMS LINCS datasets and information for each dataset about experimental reagents (small molecule perturbagens, cells, antibodies, and proteins) and experimental and data analysis protocols.

REasons for Geographic and Racial Differences in Stroke Study

REGARDS

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REGARDS is an observational study of risk factors for stroke in adults 45 years or older. 30,239 participants were recruited between January 2003 and October 2007. They completed a telephone interview followed by an in-home physical exam. Measurements included traditional risk factors such as blood pressure and cholesterol levels, and an echocardiogram of the heart. At six month intervals, participants are contacted by phone to ask about stroke symptoms, hospitalizations and general health status. The study is ongoing and will follow participants for many years.

GenomeRNAi

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GenomeRNAi is a database containing phenotypes from RNA interference (RNAi) screens in Drosophila and Homo sapiens. In addition, the database provides an updated resource of RNAi reagents and their predicted quality.

Cancer Genome Anatomy Project

CGAP

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<<<!!!<<<Noticed 26.08.2020: The NCI CBIIT instance of the CGAP no longer exist on this website. The Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer has a new home at the NCI-funded Institute for Systems Biology Cancer Genomics Cloud available at the following location: https://mitelmandatabase.isb-cgc.org>>>!!!>>>

Canadian Epigenetics, Environment and Health Research Consortium Network

CEEHRC Network

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CEEHRC represents a multi-stage funding commitment by the Canadian Institutes of Health Research (CIHR) and multiple Canadian and international partners. The overall aim is to position Canada at the forefront of international efforts to translate new discoveries in the field of epigenetics into improved human health. The two sites will focus on sequencing human reference epigenomes and developing new technologies and protocols; they will also serve as platforms for other CEEHRC funding initiatives, such as catalyst and team grants. The complementary reference epigenome mapping efforts of the two sites will focus on a range of common human diseases. The Vancouver group will focus on the role of epigenetics in the development of cancer, including lymphoma and cancers of the ovary, colon, breast, and thyroid. The Montreal team will focus on autoimmune / inflammatory, cardio-metabolic, and neuropsychiatric diseases, using studies of identical twins as well as animal models of human disease.

myExperiment

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myExperiment is a collaborative environment where scientists can safely publish their workflows and in silico experiments, share them with groups and find those of others. Workflows, other digital objects and bundles (called Packs) can now be swapped, sorted and searched like photos and videos on the Web. Unlike Facebook or MySpace, myExperiment fully understands the needs of the researcher and makes it really easy for the next generation of scientists to contribute to a pool of scientific methods, build communities and form relationships — reducing time-to-experiment, sharing expertise and avoiding reinvention. myExperiment is now the largest public repository of scientific workflows.

REFOLDdb

including: REFOLD

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REFOLD has merged to REFOLDdb. REFOLDdb is a unique database for the life sciences research community, providing annotated information for designing new refolding protocols and customizing existing methodologies. We envisage that this resource will find wide utility across broad disciplines that rely on the production of pure, active, recombinant proteins. Furthermore, the database also provides a useful overview of the recent trends and statistics in refolding technology development.We based our resource on the existing REFOLD database, which has not been updated since 2009. We redesigned the data format to be more concise, allowing consistent representations among data entries compared with the original REFOLD database. The remodeled data architecture enhances the search efficiency and improves the sustainability of the database. After an exhaustive literature search we added experimental refolding protocols from reports published 2009 to early 2017. In addition to this new data, we fully converted and integrated existing REFOLD data into our new resource.

PHI-base

Pathogen Host Interactions

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PHI-base is a web-accessible database that catalogues experimentally verified pathogenicity, virulence and effector genes from fungal, Oomycete and bacterial pathogens, which infect animal, plant, fungal and insect hosts. PHI-base is therfore an invaluable resource in the discovery of genes in medically and agronomically important pathogens, which may be potential targets for chemical intervention. In collaboration with the FRAC team, PHI-base also includes antifungal compounds and their target genes.

Conserved Domain database

CDD

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The Conserved Domain Database is a resource for the annotation of functional units in proteins. Its collection of domain models includes a set curated by NCBI, which utilizes 3D structure to provide insights into sequence/structure/function relationships

Kinetic models of biological systems

KiMoSys

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KiMoSys, a web application for quantitative KInetic MOdels of biological SYStems. Kinetic models, with the aim to understand and subsequently design the metabolism of organism of interest are constructed iteratively and require accurate experimental data for both the generation and verification of hypotheses. Therefore, there is a growing requirement for exchanging experimental data and models between the systems biology community, and to automate as much as possible the kinetic model building, editing, simulation and analysis steps.

EPIC study

European Prospective Investigation into Cancer and Nutrition Study

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The European Prospective Investigation into Cancer and Nutrition (EPIC) study is one of the largest cohort studies in the world, with more than half a million (521 000) participants recruited across 10 European countries and followed for almost 15 years. EPIC was designed to investigate the relationships between diet, nutritional status, lifestyle and environmental factors, and the incidence of cancer and other chronic diseases. EPIC investigators are active in all fields of epidemiology, and important contributions have been made in nutritional epidemiology using biomarker analysis and questionnaire information, as well as genetic and lifestyle investigations.

Ag-Analytics

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Ag-Analytics is an online open source database of various economic and environmental data. It automates the collection, formatting, and processing of several different commonly used datasets, such as the National Agricultural Statistics Service (NASS), the Agricultural Marketing Service (AMS), Risk Management agency (RMA), the PRISM weather database, and the U.S. Commodity Futures Trading Commission (CFTC). All the data have been cleaned and well-documented to save users the inconvenience of scraping and cleaning the data themselves.

DNAmod

DNA modification database

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Covalent DNA modifications have been found in numerous organisms and more are continually being discovered and characterized, as detection methods improve. Many of these modifications can affect the conformation of the DNA double helix, often resulting in downstream effects upon transcription factor binding. Some of these modifications have been demonstrated to be stable, while others are viewed as merely transient. DNAmod catalogues information on known DNA modifications, of which the well-known 5-methylcytosine is only one. It aims to profile modifications' properties, building upon data contained within the Chemical Entities of Biological Interest (ChEBI) database. It also provides literature citations and includes curated annotations on mapping techniques and natural occurrence information.

PubData

Research Data Repository Leuphana University Lüneburg

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PubData is Leuphana's institu­tional research data reposi­tory for the long-term preser­vation, documen­tation and publi­cation of research data from scienti­fic projects. PubData is main­tained by Leuphana's Media and Infor­mation Centre (MIZ) and is free of charge. The service is primarily aimed at Leuphana em­ployees and additionally at re­searchers from coope­ration partners con­tractually asso­ciated with Leuphana.

Neotoma Paleoecology Database

Neotoma

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Neotoma is a multiproxy paleoecological database that covers the Pliocene-Quaternary, including modern microfossil samples. The database is an international collaborative effort among individuals from 19 institutions, representing multiple constituent databases. There are over 20 data-types within the Neotoma Paleoecological Database, including pollen microfossils, plant macrofossils, vertebrate fauna, diatoms, charcoal, biomarkers, ostracodes, physical sedimentology and water chemistry. Neotoma provides an underlying cyberinfrastructure that enables the development of common software tools for data ingest, discovery, display, analysis, and distribution, while giving domain scientists control over critical taxonomic and other data quality issues.

Open Research Data at TUL

RDB.open

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TUL Open Research Data Repository (RDB.open) is a service addressed to the scientific and research community of the Lodz University of Technology. The main purpose of RDB.open is to collect, share and store the open research data, both during the research and after its completion, at least for the minimum period indicated by the funder or the scientists. The RDB.open is a place where research data can be openly shared, accessed and then reused by others.

NCBI Third Party Annotation

TPA

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TPA is a database that contains sequences built from the existing primary sequence data in GenBank. TPA records are retrieved through the Nucleotide Database and feature information on the sequence, how it was cataloged, and proper way to cite the sequence information.

DigiMorph

Digital Morphology

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The Digital Morphology library, part of the National Science Foundation Digital Libraries Initiative, is a dynamic archive of information on digital morphology and high-resolution X-ray computed tomography of biological specimens. Digital Morphology, part of the National Science Foundation Digital Libraries Initiative, develops and serves unique 2D and 3D visualizations of the internal and external structure of living and extinct vertebrates, and a growing number of 'invertebrates.' The Digital Morphology library contains nearly a terabyte of imagery of natural history specimens that are important to education and central to ongoing cutting-edge research efforts.

Gene Expression Nervous System Atlas

GENSAT

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The GENSAT project aims to map the expression of genes in the central nervous system of the mouse. It is a collection of pictorial gene expression maps of the brain and spinal cord of the mouse.

freeBIRD

free Bank of Injury and Emergency Research Data

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The FREEBIRD website aims to facilitate data sharing in the area of injury and emergency research in a timely and responsible manner. It has been launched by providing open access to anonymised data on over 30,000 injured patients (the CRASH-1 and CRASH-2 trials).

Europeana collections

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Europeana is the trusted source of cultural heritage brought to you by the Europeana Foundation and a large number of European cultural institutions, projects and partners. It’s a real piece of team work. Ideas and inspiration can be found within the millions of items on Europeana. These objects include: Images - paintings, drawings, maps, photos and pictures of museum objects Texts - books, newspapers, letters, diaries and archival papers Sounds - music and spoken word from cylinders, tapes, discs and radio broadcasts Videos - films, newsreels and TV broadcasts All texts are CC BY-SA, images and media licensed individually.

megx.net

Marine Ecological GenomiX

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<<<!!!<<< This repository is no longer open to the public !!! >>>!!!>>>

LINCS Data Portal

Library of Integrated Network-based Signatures Data Portal

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LINCS Data Portal provides access to LINCS data from various sources. The program has six Data and Signature Generation Centers: Drug Toxicity Signature Generation Center, HMS LINCS Center, LINCS Center for Transcriptomics, LINCS Proteomic Characterization Center for Signaling and Epigenetics, MEP LINCS Center, and NeuroLINCS Center.

CIAT Dataverse

CIAT Research Online

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The International Center for Tropical Agriculture (CIAT), a member of the CGIAR Consortium, believes that open access contributes to its mission of reducing hunger and poverty, and improving human nutrition in the tropics through research aimed at increasing the eco-efficiency of agriculture. Research data produced by CIAT and its Partners is distributed freely whenever possible. Kindly note that these datasets require proper citation and citation information is included with the metadata for each dataset.

World Register of Marine Species

WoRMS

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The World Register of Marine Species (WoRMS) integrates approximately 100 marine datbases to provide an authoritative and comprehensive list of marine organisms. WoRMS has an editorial system where taxonomic groups are managed by experts responsible for the quality of the information. WorMS register of marine species emerged from the European Register of Marine Species (ERMS) and the Flanders Marine Institute (VLIZ). WoRMS is a contribution to Lifewatch, Catalogue of Life, Encyclopedia of Life, Global Biodiversity Information Facility and the Census of Marine Life.