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Found 21 result(s)
The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.
CERN, DESY, Fermilab and SLAC have built the next-generation High Energy Physics (HEP) information system, INSPIRE. It combines the successful SPIRES database content, curated at DESY, Fermilab and SLAC, with the Invenio digital library technology developed at CERN. INSPIRE is run by a collaboration of CERN, DESY, Fermilab, IHEP, IN2P3 and SLAC, and interacts closely with HEP publishers, arXiv.org, NASA-ADS, PDG, HEPDATA and other information resources. INSPIRE represents a natural evolution of scholarly communication, built on successful community-based information systems, and provides a vision for information management in other fields of science.
The Database of Protein Disorder (DisProt) is a curated database that provides information about proteins that lack fixed 3D structure in their putatively native states, either in their entirety or in part. DisProt is a community resource annotating protein sequences for intrinsically disorder regions from the literature. It classifies intrinsic disorder based on experimental methods and three ontologies for molecular function, transition and binding partner.
MatrixDB is a freely available database focused on interactions established by extracellular proteins and polysaccharides. MatrixDB takes into account the multimetric nature of the extracellular proteins (e.g. collagens, laminins and thrombospondins are multimers). MatrixDB includes interaction data extracted from the literature by manual curation in our lab, and offers access to relevant data involving extracellular proteins provided by our IMEx partner databases through the PSICQUIC webservice, as well as data from the Human Protein Reference Database. MatrixDB is in charge of the curation of papers published in Matrix Biology since January 2009
The ACTRIS DC is designed to assist scientists with discovering and accessing atmospheric data and contains an up-to-date catalogue of available datasets in a number of databases distributed throughout the world. A site like this can never be complete, but we have aimed at including datasets from the most relevant databases to the ACTRIS project, also building on the work and experiences achieved in the EU FP6 research project Global Earth Observation and Monitoring. The focus of the web portal is validated data, but it is also possible to browse the ACTRIS data server for preliminary data (rapid delivery data) through this site. The web site allows you to search in a local metadata catalogue that contains information on actual datasets that are archived in external archives. It is set up so that you can search for data by selecting the chemical/physical variable, the data location, the database that holds the data, the type of data, the data acquisition platform, and the data matrix
ECDC is an EU agency aimed at strengthening Europe's defences against infectious diseases. The core functions cover a wide spectrum of activities: surveillance, epidemic intelligence, response, scientific advice, microbiology, preparedness, public health training, international relations, health communication, and the scientific journal Eurosurveillance. Within the field of its mission, the Centre shall: search for, collect, collate, evaluate and disseminate relevant scientific and technical data; provide scientific opinions and scientific and technical assistance including training; provide timely information to the Commission, the Member States, Community agencies and international organisations active within the field of public health; coordinate the European networking of bodies operating in the fields within the Centre's mission, including networks that emerge from public health activities supported by the Commission and operating the dedicated surveillance networks; exchange information, expertise and best practices, and facilitate the development and implementation of joint actions.
The name Earth Online derives from ESA's Earthnet programme. Earthnet prepares and attracts new ESA Earth Observation missions by setting the international cooperation scheme, preparing the basic infrastructure, building the scientific and application Community and competency in Europe to define and set-up own European Programmes in consultation with member states. Earth Online is the entry point for scientific-technical information on Earth Observation activities by the European Space Agency (ESA). The web portal provides a vast amount of content, grown and collected over more than a decade: Detailed technical information on Earth Observation (EO) missions; Satellites and sensors; EO data products & services; Online resources such as catalogues and library; Applications of satellite data; Access to promotional satellite imagery. After 10 years of operations on distinct sites, the two principal portals of ESA Earth Observation - Earth Online (earth.esa.int) and the Principal Investigator's Portal (eopi.esa.int) have moved to a new platform. ESA's technical and scientific earth observation user communities will from now on be served from a single portal, providing a modern and easy-to-use interface to our services and data.
The CATH database is a hierarchical domain classification of protein structures in the Protein Data Bank. Protein structures are classified using a combination of automated and manual procedures. There are four major levels in the CATH hierarchy; Class, Architecture, Topology and Homologous superfamily.
Real-Time Database for high-resolution Neutron Monitor measurements. NMDB provides access to Neutron Monitor measurements from stations around the world. The goal of NMDB is to provide easy access to all Neutron Monitor measurements through an easy to use interface. NMDB provides access to real-time as well as historical data.
EMAGE (e-Mouse Atlas of Gene Expression) is an online biological database of gene expression data in the developing mouse (Mus musculus) embryo. The data held in EMAGE is spatially annotated to a framework of 3D mouse embryo models produced by EMAP (e-Mouse Atlas Project). These spatial annotations allow users to query EMAGE by spatial pattern as well as by gene name, anatomy term or Gene Ontology (GO) term. EMAGE is a freely available web-based resource funded by the Medical Research Council (UK) and based at the MRC Human Genetics Unit in the Institute of Genetics and Molecular Medicine, Edinburgh, UK.
GWAS Central (previously the Human Genome Variation database of Genotype-to-Phenotype information) is a database of summary level findings from genetic association studies, both large and small. We actively gather datasets from public domain projects, and encourage direct data submission from the community.
Europeana is the trusted source of cultural heritage brought to you by the Europeana Foundation and a large number of European cultural institutions, projects and partners. It’s a real piece of team work. Ideas and inspiration can be found within the millions of items on Europeana. These objects include: Images - paintings, drawings, maps, photos and pictures of museum objects Texts - books, newspapers, letters, diaries and archival papers Sounds - music and spoken word from cylinders, tapes, discs and radio broadcasts Videos - films, newsreels and TV broadcasts All texts are CC BY-SA, images and media licensed individually.
The Bavarian Archive for Speech Signals (BAS) is a public institution hosted by the University of Munich. This institution was founded with the aim of making corpora of current spoken German available to both the basic research and the speech technology communities via a maximally comprehensive digital speech-signal database. The speech material will be structured in a manner allowing flexible and precise access, with acoustic-phonetic and linguistic-phonetic evaluation forming an integral part of it.
The 1000 Genomes Project is an international collaboration to produce an extensive public catalog of human genetic variation, including SNPs and structural variants, and their haplotype contexts. This resource will support genome-wide association studies and other medical research studies. The genomes of about 2500 unidentified people from about 25 populations around the world will be sequenced using next-generation sequencing technologies. The results of the study will be freely and publicly accessible to researchers worldwide. The International Genome Sample Resource (IGSR) has been established at EMBL-EBI to continue supporting data generated by the 1000 Genomes Project, supplemented with new data and new analysis.
virus mentha archives evidence about viral interactions collected from different sources and presents these data in a complete and comprehensive way. Its data comes from manually curated protein-protein interaction databases that have adhered to the IMEx consortium. virus mentha is a resource that offers a series of tools to analyse selected proteins in the context of a network of interactions. Protein interaction databases archive protein-protein interaction (PPI) information from published articles. However, no database alone has sufficient literature coverage to offer a complete resource to investigate "the interactome". virus mentha's approach generates every week a consistent interactome (graph). Most importantly, the procedure assigns to each interaction a reliability score that takes into account all the supporting evidence. virus mentha offers direct access to viral families such as: Orthomyxoviridae, Orthoretrovirinae and Herpesviridae plus, it offers the unique possibility of searching by host organism. The website and the graphical application are designed to make the data stored in virus mentha accessible and analysable to all users.virus mentha superseeds VirusMINT. The Source databases are: MINT, DIP, IntAct, MatrixDB, BioGRID.
The European Soil Data Centre (ESDAC) is the thematic centre for soil related data in Europe. Its ambition is to be the single reference point for and to host all relevant soil data and information at European level. It contains a number of resources that are organized and presented in various ways: datasets, services/applications, maps, documents, events, projects and external links.
The Database explores the interactions of chemicals and proteins. It integrates information about interactions from metabolic pathways, crystal structures, binding experiments and drug-target relationships. Inferred information from phenotypic effects, text mining and chemical structure similarity is used to predict relations between chemicals. STITCH further allows exploring the network of chemical relations, also in the context of associated binding proteins.