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Found 285 result(s)
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PRISM Dataverse is the institutional data repository of the University of Calgary, which has its purpose in digital archiving and sharing of research data from researchers. PRISM Dataverse is a data repository hosted through Borealis, a service of the Ontario Council of University Libraries and supported by University of Calgary's Libraries and Cultural Resources. PRISM Dataverse enables scholars to easily deposit data, create data-specific metadata for searchability and publish their datasets.
<<<!!!<<< This repository is no longer available. >>>!!!>>> NetPath is currently one of the largest open-source repository of human signaling pathways that is all set to become a community standard to meet the challenges in functional genomics and systems biology. Signaling networks are the key to deciphering many of the complex networks that govern the machinery inside the cell. Several signaling molecules play an important role in disease processes that are a direct result of their altered functioning and are now recognized as potential therapeutic targets. Understanding how to restore the proper functioning of these pathways that have become deregulated in disease, is needed for accelerating biomedical research. This resource is aimed at demystifying the biological pathways and highlights the key relationships and connections between them. Apart from this, pathways provide a way of reducing the dimensionality of high throughput data, by grouping thousands of genes, proteins and metabolites at functional level into just several hundreds of pathways for an experiment. Identifying the active pathways that differ between two conditions can have more explanatory power than just a simple list of differentially expressed genes and proteins.
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The Canadian Astronomy Data Centre (CADC) was established in 1986 by the National Research Council of Canada (NRC), through a grant provided by the Canadian Space Agency (CSA). Over the past 30 years the CADC has evolved from an archiving centre---hosting data from Hubble Space Telescope, Canada-France-Hawaii Telescope, the Gemini observatories, and the James Clerk Maxwell Telescope---into a Science Platform for data-intensive astronomy. The CADC, in partnership with Shared Services Canada, Compute Canada, CANARIE and the university community (funded through the Canadian Foundation for Innovation), offers cloud computing, user-managed storage, group management, and data publication services, in addition to its ongoing mission to provide permanent storage for major data collections. Located at NRC Herzberg Astronomy and Astrophysics Research Centre in Victoria, BC, the CADC staff consists of professional astronomers, software developers, and operations staff who work with the community to develop and deliver leading-edge services to advance Canadian research. The CADC plays a leading role in international efforts to improve the scientific/technical landscape that supports data intensive science. This includes leadership roles in the International Virtual Observatory Alliance and participation in organizations like the Research Data Alliance, CODATA, and the World Data Systems. CADC also contributes significantly to future Canadian projects like the Square Kilometre Array and TMT. In 2019, the Canadian Astronomy Data Centre (CADC) delivered over 2 Petabytes of data (over 200 million individual files) to thousands of astronomers in Canada and in over 80 other countries. The cloud processing system completed over 6 million jobs (over 1100 core years) in 2019.
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Agri-environmental Research Data collection is part of the University of Guelph Research Data Repositories (University of Guelph Dataverse). The purpose of this collection is to provide access to, and long-term stewardship of, agricultural and environmental data created at or in cooperation with the University of Guelph.
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The University of Northern British Columbia Dataverse is a research data repository for research data from UNBC researchers. Files are held in a secure environment on Canadian servers. The platform makes it possible for researchers to deposit data, create appropriate metadata, and version documents as they work. Researchers can choose to make content available publicly, to specific individuals, or to keep it locked.
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The Canadian Opinion Research Archive at Queen's University makes available commercial and independent surveys to the academic, research and journalistic communities. Founded in 1992, CORA contains hundreds of surveys including thousands of discrete items collected by major commercial Canadian firms dating back to the 1970s. CORA is continually adding new surveys and is always soliciting new data from commercial research firms, independent think tanks, research institutes, NGOs, and academic researchers. This website also includes readily accessible results from these surveys, tracking Canadian opinion over time on frequently asked survey questions, as well as tabular results from recent Canadian surveys, and more general information on polling. This material is made available as a public service by CORA and its partners.
The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.
The University of Toronto Dataverse is a research data repository for our faculty, students, and staff. Files are held in a secure environment on Canadian servers. Researchers can choose to make content available publicly, to specific individuals, or to restrict access.
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<<<!!!<<< 2021-03-19: The repository is no longer available >>>!!!>>> The National Contaminants Information System was begun as part of the Department's Green Plan. The NCIS is a computerized warehouse of information on toxic chemicals in fish, other aquatic life and their habitats. It was built to help manage the growing base of data and information.
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<<<!!!<<< Genome data generated by BC Genome Sciences Centre is no longer available through this site as it is regularly deposited into controlled data repositories such as the European Genome Phenome Archive (EGA); ICGC (International Cancer Genome Consortium) and the Genome Data Commons (GDC) >>>!!!>>> Using serial analysis of gene expression (SAGE) and microarrays, we are examining total mRNA populations in all developmental stages, both in whole worms and in specific cells and tissues. In addition, we are building promoter::GFP constructs to monitor gene expression in transgenic worms, focusing on C. elegans genes that have human orthologues. Also available are web-based PCR primer design tools, and access to information about our C. elegans Fosmid library.
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Public access to open data from the Regional Municipality of Waterloo (the cities of Kitchener, Cambridge, and Waterloo, and the townships of Wellesley, Woolwich, Wilmot, and North Dumfries).
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The Canada Open Data Project provides Government of Canada data to the public as potential driver for economic innovation. Searchable and browsable raw data is available for download, and the public can recommend specific data be made available.
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We developed a method, ChIP-sequencing (ChIP-seq), combining chromatin immunoprecipitation (ChIP) and massively parallel sequencing to identify mammalian DNA sequences bound by transcription factors in vivo. We used ChIP-seq to map STAT1 targets in interferon-gamma (IFN-gamma)-stimulated and unstimulated human HeLa S3 cells, and compared the method's performance to ChIP-PCR and to ChIP-chip for four chromosomes.For both Chromatin- immunoprecipation Transcription Factors and Histone modifications. Sequence files and the associated probability files are also provided.
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<<<!!!<<< This repository is no longer available. >>>!!!>>> Message since 2018-06: This virtual host is being reconstructed.
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The Cystic Fibrosis Mutation Database (CFTR1) was initiated by the Cystic Fibrosis Genetic Analysis Consortium in 1989 to increase and facilitate communications among CF researchers, and is maintained by the Cystic Fibrosis Centre at the Hospital for Sick Children in Toronto. The specific aim of the database is to provide up to date information about individual mutations in the CFTR gene. In a major upgrade in 2010, all known CFTR mutations and sequence variants have been converted to the standard nomenclature recommended by the Human Genome Variation Society.
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TopFIND is a protein-centric database for the annotation of protein termini currently in its third version. Non-canonical protein termini can be the result of multiple different biological processes, including pre-translational processes such as alternative splicing and alternative translation initiation or post-translational protein processing by proteases that cleave proteases as part of protein maturation or as a regulatory modification. Accordingly, protein termini evidence in TopFIND is inferred from other databases such as ENSEMBL transcripts, TISdb for alternative translation initiation, MEROPS for protein cleavage by proteases, and UniProt for canonical and protein isoform start sites.
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The University of Regina Library offers our institution's researchers the opportunity to store (and share, if appropriate) their research data in our University of Regina Dataverse.
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The Catalog of Inferred Sequence Binding Preferences (CIS-BP) is a library of transcription factor (TF) DNA binding motifs and specificities. The data are organized in a user friendly manner for ease of searching, browsing, and downloading. CIS-BP also includes built-in web tools for scanning DNA sequences for putative TF binding sites, predicting the DNA binding motif of a given TF, and identifying a TF that might recognize a given DNA motif.