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The HUGO Gene Nomenclature Committee (HGNC) assigned unique gene symbols and names to over 35,000 human loci, of which around 19,000 are protein coding. This curated online repository of HGNC-approved gene nomenclature and associated resources includes links to genomic, proteomic and phenotypic information, as well as dedicated gene family pages.
The Gene database provides detailed information for known and predicted genes defined by nucleotide sequence or map position. Gene supplies gene-specific connections in the nexus of map, sequence, expression, structure, function, citation, and homology data. Unique identifiers are assigned to genes with defining sequences, genes with known map positions, and genes inferred from phenotypic information. These gene identifiers are used throughout NCBI's databases and tracked through updates of annotation. Gene includes genomes represented by NCBI Reference Sequences (or RefSeqs) and is integrated for indexing and query and retrieval from NCBI's Entrez and E-Utilities systems.
FungiDB belongs to the EuPathDB family of databases and is an integrated genomic and functional genomic database for the kingdom Fungi. FungiDB was first released in early 2011 as a collaborative project between EuPathDB and the group of Jason Stajich (University of California, Riverside). At the end of 2015, FungiDB was integrated into the EuPathDB bioinformatic resource center. FungiDB integrates whole genome sequence and annotation and also includes experimental and environmental isolate sequence data. The database includes comparative genomics, analysis of gene expression, and supplemental bioinformatics analyses and a web interface for data-mining.
The Entrez Protein Clusters database contains annotation information, publications, structures and analysis tools for related protein sequences encoded by complete genomes. The data available in the Protein Clusters Database is generated from prokaryotic genomic studies and is intended to assist researchers studying micro-organism evolution as well as other biological sciences. Available genomes include plants and viruses as well as organelles and microbial genomes.
The Global Hydrology Resource Center (GHRC) provides both historical and current Earth science data, information, and products from satellite, airborne, and surface-based instruments. GHRC acquires basic data streams and produces derived products from many instruments spread across a variety of instrument platforms.
Pubchem contains 3 databases. 1. PubChem BioAssay: The PubChem BioAssay Database contains bioactivity screens of chemical substances described in PubChem Substance. It provides searchable descriptions of each bioassay, including descriptions of the conditions and readouts specific to that screening procedure. 2. PubChem Compound: The PubChem Compound Database contains validated chemical depiction information provided to describe substances in PubChem Substance. Structures stored within PubChem Compounds are pre-clustered and cross-referenced by identity and similarity groups. 3. PubChem Substance. The PubChem Substance Database contains descriptions of samples, from a variety of sources, and links to biological screening results that are available in PubChem BioAssay. If the chemical contents of a sample are known, the description includes links to PubChem Compound.
This resource allows users to search for and compare influenza virus genomes and gene sequences taken from GenBank. It also provides a virus sequence annotation tool and links to other influenza resources: NIAID project, JCVI Flu, Influenza research database, CDC Flu, Vaccine Selection and WHO Flu. NOTE: In Fall 2024, NCBI plans to redirect the Influenza Virus Resource to NCBI Virus, possibly as soon as September. For most up-to-date and accurate virus data, see NCBI Virus https://www.re3data.org/repository/r3d100014322
AceView provides a curated, comprehensive and non-redundant sequence representation of all public mRNA sequences (mRNAs from GenBank or RefSeq, and single pass cDNA sequences from dbEST and Trace). These experimental cDNA sequences are first co-aligned on the genome then clustered into a minimal number of alternative transcript variants and grouped into genes. Using exhaustively and with high quality standards the available cDNA sequences evidences the beauty and complexity of mammals’ transcriptome, and the relative simplicity of the nematode and plant transcriptomes. Genes are classified according to their inferred coding potential; many presumably non-coding genes are discovered. Genes are named by Entrez Gene names when available, else by AceView gene names, stable from release to release. Alternative features (promoters, introns and exons, polyadenylation signals) and coding potential, including motifs, domains, and homologies are annotated in depth; tissues where expression has been observed are listed in order of representation; diseases, phenotypes, pathways, functions, localization or interactions are annotated by mining selected sources, in particular PubMed, GAD and Entrez Gene, and also by performing manual annotation, especially in the worm. In this way, both the anatomy and physiology of the experimentally cDNA supported human, mouse and nematode genes are thoroughly annotated.
PAGER (Prompt Assessment of Global Earthquakes for Response) is an automated system that produces content concerning the impact of significant earthquakes around the world, informing emergency responders, government and aid agencies, and the media of the scope of the potential disaster. PAGER rapidly assesses earthquake impacts by comparing the population exposed to each level of shaking intensity with models of economic and fatality losses based on past earthquakes in each country or region of the world. Earthquake alerts – which were formerly sent based only on event magnitude and location, or population exposure to shaking – now will also be generated based on the estimated range of fatalities and economic losses. PAGER uses these earthquake parameters to calculate estimates of ground shaking by using the methodology and software developed for ShakeMaps. ShakeMap sites provide near-real-time maps of ground motion and shaking intensity following significant earthquakes. These maps are used by federal, state, and local organizations, both public and private, for post-earthquake response and recovery, public and scientific information, as well as for preparedness exercises and disaster planning.
The Precipitation Processing System (PPS) evolved from the Tropical Rainfall Measuring Mission (TRMM) Science Data and Information System (TSDIS). The purpose of the PPS is to process, analyze and archive data from the Global Precipitation Measurement (GPM) mission, partner satellites and the TRMM mission. The PPS also supports TRMM by providing validation products from TRMM ground radar sites. All GPM, TRMM and Partner public data products are available to the science community and the general public from the TRMM/GPM FTP Data Archive. Please note that you need to register to be able to access this data. Registered users can also search for GPM, partner and TRMM data, order custom subsets and set up subscriptions using our PPS Data Products Ordering Interface (STORM)
This interface provides access to several types of data related to the Chesapeake Bay. Bay Program databases can be queried based upon user-defined inputs such as geographic region and date range. Each query results in a downloadable, tab- or comma-delimited text file that can be imported to any program (e.g., SAS, Excel, Access) for further analysis. Comments regarding the interface are encouraged. Questions in reference to the data should be addressed to the contact provided on subsequent pages.
This site is dedicated to making high value health data more accessible to entrepreneurs, researchers, and policy makers in the hopes of better health outcomes for all. In a recent article, Todd Park, United States Chief Technology Officer, captured the essence of what the Health Data Initiative is all about and why our efforts here are so important.
<<<!!!<<< Effective May 2024, NCBI's Genome resource will no longer be available. NCBI Genome data can now be found on the NCBI Datasets taxonomy pages. https://www.re3data.org/repository/r3d100014298 >>>!!!>>> The Genome database contains annotations and analysis of eukaryotic and prokaryotic genomes, as well as tools that allow users to compare genomes and gene sequences from humans, microbes, plants, viruses and organelles. Users can browse by organism, and view genome maps and protein clusters.
<<<!!!<<< The repository is no longer available - Data previously on the site are now available at ftp://ftp.ncbi.nlm.nih.gov/pub/mhc/mhc/Final Archive. >>>!!!>>> The dbMHC database provides an open, publicly accessible platform for DNA and clinical data related to the human Major Histocompatibility Complex (MHC). The dbMHC provides access to human leukocyte antigen (HLA) sequences, HLA allele and haplotype frequencies, and clinical datasets.
The NCBI database of Genotypes and Phenotypes archives and distributes the results of studies that have investigated the interaction of genotype and phenotype, including genome-wide association studies, medical sequencing, molecular diagnostic assays, and association between genotype and non-clinical traits. The database provides summaries of studies, the contents of measured variables, and original study document text. dbGaP provides two types of access for users, open and controlled. Through the controlled access, users may access individual-level data such as phenotypic data tables and genotypes.
This centre receives and archives precipitation chemistry data and complementary information from stations around the world. Data archived by this centre are accessible via connections with the WDCPC database. Freely available data from regional and national programmes with their own Web sites are accessible via links to these sites. The WDCPC is one of six World Data Centres in the World Meteorological Organization Global Atmosphere Watch (GAW). The focus on precipitation chemistry is described in the GAW Precipitation Chemistry Programme. Guidance on all aspects of collecting precipitation for chemical analysis is provided in the Manual for the GAW Precipitation Chemistry Programme (WMO-GAW Report No. 160).
The Radio Telescope Data Center (RTDC) reduces, archives, and makes available on its web site data from SMA and the CfA Millimeter-wave Telescope. The whole-Galaxy CO survey presented in Dame et al. (2001) is a composite of 37 separate surveys. The data from most of these surveys can be accessed. Larger composites of these surveys are available separately.
The NCBI Short Genetic Variations database, commonly known as dbSNP, catalogs short variations in nucleotide sequences from a wide range of organisms. These variations include single nucleotide variations, short nucleotide insertions and deletions, short tandem repeats and microsatellites. Short Genetic Variations may be common, thus representing true polymorphisms, or they may be rare. Some rare human entries have additional information associated withthem, including disease associations, genotype information and allele origin, as some variations are somatic rather than germline events. ***NCBI will phase out support for non-human organism data in dbSNP and dbVar beginning on September 1, 2017***
The JPL Tropical Cyclone Information System (TCIS) was developed to support hurricane research. There are three components to TCIS; a global archive of multi-satellite hurricane observations 1999-2010 (Tropical Cyclone Data Archive), North Atlantic Hurricane Watch and ASA Convective Processes Experiment (CPEX) aircraft campaign. Together, data and visualizations from the real time system and data archive can be used to study hurricane process, validate and improve models, and assist in developing new algorithms and data assimilation techniques.
The International Ocean Discovery Program’s (IODP) Gulf Coast Repository (GCR) is located in the Research Park on the Texas A&M University campus in College Station, Texas. This repository stores DSDP, ODP, and IODP cores from the Pacific Ocean, the Caribbean Sea and Gulf of Mexico, and the Southern Ocean. A satellite repository at Rutgers University houses New Jersey/Delaware land cores 150X and 174AX.
SoyBase is a professionally curated repository for genetics, genomics and related data resources for soybean. It contains current genetic, physical and genomic sequence maps integrated with qualitative and quantitative traits. SoyBase includes annotated "Williams 82" genomic sequence and associated data mining tools. The repository maintains controlled vocabularies for soybean growth, development, and traits that are linked to more general plant ontologies.