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This Animal Quantitative Trait Loci (QTL) database (Animal QTLdb) is designed to house all publicly available QTL and trait mapping data (i.e. trait and genome location association data; collectively called "QTL data" on this site) on livestock animal species for easily locating and making comparisons within and between species. New database tools are continuely added to align the QTL and association data to other types of genome information, such as annotated genes, RH / SNP markers, and human genome maps. Besides the QTL data from species listed below, the QTLdb is open to house QTL/association date from other animal species where feasible. Note that the JAS along with other journals, now require that new QTL/association data be entered into a QTL database as part of their publication requirements.
The ENCODE Encyclopedia organizes the most salient analysis products into annotations, and provides tools to search and visualize them. The Encyclopedia has two levels of annotations: Integrative-level annotations integrate multiple types of experimental data and ground level annotations. Ground-level annotations are derived directly from the experimental data, typically produced by uniform processing pipelines.
bugwood.org is the host website of the Center for Invasive Species and Ecosystem Health at the University of Georgia (Formerly: Bugwood Network). The Center aims to develop, consolidate and disseminate information and programmes focused on invasive species, forest health, natural resources and agricultural management through technology development, programmes implementation, training, applied research and public awareness at state, regional, national and international levels. The site gives details of its products (Bugwood Image Database; Early Detection and Distribution Mapping and Bugwoodwiki). Details of its projects, services and personnel are provided. Users can also access image databases on Forestry, Insects, IPM, Invasive Species, Forest Pests, weed and Bark Beetle.
Our knowledge of the many life-forms on Earth - of animals, plants, fungi, protists and bacteria - is scattered around the world in books, journals, databases, websites, specimen collections, and in the minds of people everywhere. Imagine what it would mean if this information could be gathered together and made available to everyone – anywhere – at a moment’s notice. This dream is becoming a reality through the Encyclopedia of Life.
The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.
MorphoSource is a data repository specialized for 3D representing physical objects used in research in education (e.g., from museum or laboratory collections). It allows researchers and museum collection staff to store and organize, share, and distribute their own 3d data. Furthermore any registered user can immediately search for and download 3d morphological data sets that have been made accessible through the consent of data authors.
The Paleobiology Database (PaleoBioDB) is a non-governmental, non-profit public resource for paleontological data. It has been organized and operated by a multi-disciplinary, multi-institutional, international group of paleobiological researchers. Its purpose is to provide global, collection-based occurrence and taxonomic data for organisms of all geological ages, as well data services to allow easy access to data for independent development of analytical tools, visualization software, and applications of all types. The Database’s broader goal is to encourage and enable data-driven collaborative efforts that address large-scale paleobiological questions.
ArrayExpress is one of the major international repositories for high-throughput functional genomics data from both microarray and high-throughput sequencing studies, many of which are supported by peer-reviewed publications. Data sets are submitted directly to ArrayExpress and curated by a team of specialist biological curators. In the past (until 2018) datasets from the NCBI Gene Expression Omnibus database were imported on a weekly basis. Data is collected to MIAME and MINSEQE standards.
EMAGE (e-Mouse Atlas of Gene Expression) is an online biological database of gene expression data in the developing mouse (Mus musculus) embryo. The data held in EMAGE is spatially annotated to a framework of 3D mouse embryo models produced by EMAP (e-Mouse Atlas Project). These spatial annotations allow users to query EMAGE by spatial pattern as well as by gene name, anatomy term or Gene Ontology (GO) term. EMAGE is a freely available web-based resource funded by the Medical Research Council (UK) and based at the MRC Human Genetics Unit in the Institute of Genetics and Molecular Medicine, Edinburgh, UK.
<<<!!!<<< The ArkDB is now CLOSED With apologies to anyone who still relies on the ArkDB data system or map-drawing tools, we've had to take the difficult decision to shut down the ArkDB system. We've not been funded to maintain it for many years now and have kept it in the air as best we could with the time that we had available but recent changes in personnel and continuing updates to the underpinning libraries mean that the effort required to keep it going outweighs the perceived benefits. If you feel that this is the wrong decision, please contact us to let us know and we'll see what we can do together You can always contact us on our Roslin Bioinformatics email address (roslin.bioinformatics@roslin.ed.ac.uk) The Roslin Bioinformatics Team 21st November 2018 >>>!!!>>>
The MMRRC is the nation’s premier national public repository system for mutant mice. Funded by the NIH continuously since 1999, the MMRRC archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by the biomedical research community. The MMRRC consists of a national network of breeding and distribution repositories and an Informatics Coordination and Service Center located at 4 major academic centers across the nation. The MMRRC is committed to upholding the highest standards of experimental design and quality control to optimize the reproducibility of research studies using mutant mice.
Neotoma is a multiproxy paleoecological database that covers the Pliocene-Quaternary, including modern microfossil samples. The database is an international collaborative effort among individuals from 19 institutions, representing multiple constituent databases. There are over 20 data-types within the Neotoma Paleoecological Database, including pollen microfossils, plant macrofossils, vertebrate fauna, diatoms, charcoal, biomarkers, ostracodes, physical sedimentology and water chemistry. Neotoma provides an underlying cyberinfrastructure that enables the development of common software tools for data ingest, discovery, display, analysis, and distribution, while giving domain scientists control over critical taxonomic and other data quality issues.
The Ensembl genome annotation system, developed jointly by the EBI and the Wellcome Trust Sanger Institute, has been used for the annotation, analysis and display of vertebrate genomes since 2000. Since 2009, the Ensembl site has been complemented by the creation of five new sites, for bacteria, protists, fungi, plants and invertebrate metazoa, enabling users to use a single collection of (interactive and programatic) interfaces for accessing and comparing genome-scale data from species of scientific interest from across the taxonomy. In each domain, we aim to bring the integrative power of Ensembl tools for comparative analysis, data mining and visualisation across genomes of scientific interest, working in collaboration with scientific communities to improve and deepen genome annotation and interpretation.
FaceBase is a collaborative NIDCR-funded project that houses comprehensive data in support of advancing research into craniofacial development and malformation. It serves as a community resource by curating large datasets of a variety of types from the craniofacial research community and sharing them via this website. Practices emphasize a comprehensive and multidisciplinary approach to understanding the developmental processes that create the face. The data offered spotlights high-throughput genetic, molecular, biological, imaging and computational techniques. One of the missions of this project is to facilitate cooperation and collaboration between the central coordinating center (ie, the Hub) and the craniofacial research community.
The Ensembl project produces genome databases for vertebrates and other eukaryotic species. Ensembl is a joint project between the European Bioinformatics Institute (EBI) and the Wellcome Trust Sanger Institute (WTSI) to develop a software system that produces and maintains automatic annotation on selected genomes.The Ensembl project was started in 1999, some years before the draft human genome was completed. Even at that early stage it was clear that manual annotation of 3 billion base pairs of sequence would not be able to offer researchers timely access to the latest data. The goal of Ensembl was therefore to automatically annotate the genome, integrate this annotation with other available biological data and make all this publicly available via the web. Since the website's launch in July 2000, many more genomes have been added to Ensembl and the range of available data has also expanded to include comparative genomics, variation and regulatory data. Ensembl is a joint project between European Bioinformatics Institute (EBI), an outstation of the European Molecular Biology Laboratory (EMBL), and the Wellcome Trust Sanger Institute (WTSI). Both institutes are located on the Wellcome Trust Genome Campus in Hinxton, south of the city of Cambridge, United Kingdom.
The Arctic Data Center is the primary data and software repository for the Arctic section of NSF Polar Programs. The Center helps the research community to reproducibly preserve and discover all products of NSF-funded research in the Arctic, including data, metadata, software, documents, and provenance that links these together. The repository is open to contributions from NSF Arctic investigators, and data are released under an open license (CC-BY, CC0, depending on the choice of the contributor). All science, engineering, and education research supported by the NSF Arctic research program are included, such as Natural Sciences (Geoscience, Earth Science, Oceanography, Ecology, Atmospheric Science, Biology, etc.) and Social Sciences (Archeology, Anthropology, Social Science, etc.). Key to the initiative is the partnership between NCEAS at UC Santa Barbara, DataONE, and NOAA’s NCEI, each of which bring critical capabilities to the Center. Infrastructure from the successful NSF-sponsored DataONE federation of data repositories enables data replication to NCEI, providing both offsite and institutional diversity that are critical to long term preservation.