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!!! <<< Genome data generated by BC Genome Sciences Centre is no longer available through this site as it is regularly deposited into controlled data repositories such as the European Genome Phenome Archive (EGA); ICGC (International Cancer Genome Consortium) and the Genome Data Commons (GDC) <<< !!! Using serial analysis of gene expression (SAGE) and microarrays, we are examining total mRNA populations in all developmental stages, both in whole worms and in specific cells and tissues. In addition, we are building promoter::GFP constructs to monitor gene expression in transgenic worms, focusing on C. elegans genes that have human orthologues. Also available are web-based PCR primer design tools, and access to information about our C. elegans Fosmid library.
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The KiezDeutsch-Korpus (KiDKo) has been developed by project B6 (PI: Heike Wiese) of the collaborative research centre Information Structure (SFB 632) at the University of Potsdam from 2008 to 2015. KiDKo is a multi-modal digital corpus of spontaneous discourse data from informal, oral peer group situations in multi- and monoethnic speech communities. KiDKo contains audio data from self-recordings, with aligned transcriptions (i.e., at every point in a transcript, one can access the corresponding area in the audio file). The corpus provides parts-of-speech tags as well as an orthographically normalised layer (Rehbein & Schalowski 2013). Another annotation level provides information on syntactic chunks and topological fields. There are several complementary corpora: KiDKo/E (Einstellungen - "attitudes") captures spontaneous data from the public discussion on Kiezdeutsch: it assembles emails and readers' comments posted in reaction to media reports on Kiezdeutsch. By doing so, KiDKo/E provides data on language attitudes, language perceptions, and language ideologies, which became apparent in the context of the debate on Kiezdeutsch, but which frequently related to such broader domains as multilingualism, standard language, language prestige, and social class. KiDKo/LL ("Linguistic Landscape") assembles photos of written language productions in public space from the context of Kiezdeutsch, for instance love notes on walls, park benches, and playgrounds, graffiti in house entrances, and scribbled messages on toilet walls. Contains materials in following languages: Spanish, Italian, Greek, Kurdish, Swedish, French, Croatian, Arabic, Turkish. The corpus is available online via the Hamburger Zentrum für Sprachkorpora (HZSK) https://corpora.uni-hamburg.de/secure/annis-switch.php?instance=kidko .
STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations; they are derived from four sources: - Genomic Context - High-throughput Experiments - (Conserved) Coexpression - Previous Knowledge STRING quantitatively integrates interaction data from these sources for a large number of organisms, and transfers information between these organisms where applicable.
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Avibase is an extensive database information system about all birds of the world, containing over 60 million records about 10,000 species and 22,000 subspecies of birds, including distribution information, taxonomy, synonyms in several languages and more. This site is managed by Denis Lepage and hosted by Bird Studies Canada, the Canadian copartner of Birdlife International. Avibase has been a work in progress since 1992 and I am now pleased to offer it as a service to the bird-watching and scientific community.
The IMEx consortium is an international collaboration between a group of major public interaction data providers who have agreed to share curation effort and develop and work to a single set of curation rules when capturing data from both directly deposited interaction data or from publications in peer-reviewed journals, capture full details of an interaction in a “deep” curation model, perform a complete curation of all protein-protein interactions experimentally demonstrated within a publication, make these interaction available in a single search interface on a common website, provide the data in standards compliant download formats, make all IMEx records freely accessible under the Creative Commons Attribution License
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The BCDC serves the research data obtained, and the data syntheses assembled, by researchers within the Bjerknes Centre for Climate Research. Furthermore it is open for all interested scientists independent of institution. All data from the different disciplines (e.g. geology, oceanography, biology, model community) will be archived in a long-term repository, interconnected and made publicly available by the BCDC. BCDC has collaborations with many international data repositories and actively archives metadata and data at those ensuring quality and FAIRness. BCDC has it's main focus on services for data management for external and internal funded projects in the field of climate research, provides data management plans and ensures that data is archived accordingly according to the best practices in the field. The data management services rank from project work for small external funded project to top-of-the-art data management services for research infrastructures on the ESFRI roadmap (e.g. RI ICOS – Integrated Carbon Observation System) and for provides products and services for Copernicus Marine Environmental Monitoring Services. In addition BCDC is advising various communities on data management services e.g. IOC UNESCO, OECD, IAEA and various funding agencies. BCDC will become an Associated Data Unit (ADU) under IODE, International Oceanographic Data and Information Exchange, a worldwide network that operates under the auspices of the Intergovernmental Oceanographic Commission of UNESCO and aims at becoming a part of ICSU World Data System.
The Tropospheric Ozone Assessment Report (TOAR) database of global surface observations is the world's most extensive collection of surface ozone measurements and includes also data on other air pollutants and on weather for some regions. Measurements from 1970 to 2019 (Version 1) have been collected in a relational database, and are made available via a graphical web interface, a REST service (https://toar-data.fz-juelich.de/api/v1) and as aggregated products on PANGAEA (https://doi.pangaea.de/10.1594/PANGAEA.876108). Measurements from 1970 to present (Version 2) are being collected in a relational database, and are made available via a REST service (https://toar-data.fz-juelich.de/api/v2).
EDINA delivers online services and tools to benefit students, teachers and researchers in UK Higher and Further Education and beyond.
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We developed a method, ChIP-sequencing (ChIP-seq), combining chromatin immunoprecipitation (ChIP) and massively parallel sequencing to identify mammalian DNA sequences bound by transcription factors in vivo. We used ChIP-seq to map STAT1 targets in interferon-gamma (IFN-gamma)-stimulated and unstimulated human HeLa S3 cells, and compared the method's performance to ChIP-PCR and to ChIP-chip for four chromosomes.For both Chromatin- immunoprecipation Transcription Factors and Histone modifications. Sequence files and the associated probability files are also provided.
The DIP database catalogs experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein interactions. The data stored within the DIP database were curated, both, manually by expert curators and also automatically using computational approaches that utilize the the knowledge about the protein-protein interaction networks extracted from the most reliable, core subset of the DIP data. Please, check the reference page to find articles describing the DIP database in greater detail. The Database of Ligand-Receptor Partners (DLRP) is a subset of DIP (Database of Interacting Proteins). The DLRP is a database of protein ligand and protein receptor pairs that are known to interact with each other. By interact we mean that the ligand and receptor are members of a ligand-receptor complex and, unless otherwise noted, transduce a signal. In some instances the ligand and/or receptor may form a heterocomplex with other ligands/receptors in order to be functional. We have entered the majority of interactions in DLRP as full DIP entries, with links to references and additional information
The EUDAT project aims to contribute to the production of a Collaborative Data Infrastructure (CDI). The project´s target is to provide a pan-European solution to the challenge of data proliferation in Europe's scientific and research communities. The EUDAT vision is to support a Collaborative Data Infrastructure which will allow researchers to share data within and between communities and enable them to carry out their research effectively. EUDAT aims to provide a solution that will be affordable, trustworthy, robust, persistent and easy to use. EUDAT comprises 26 European partners, including data centres, technology providers, research communities and funding agencies from 13 countries. B2FIND is the EUDAT metadata service allowing users to discover what kind of data is stored through the B2SAFE and B2SHARE services which collect a large number of datasets from various disciplines. EUDAT will also harvest metadata from communities that have stable metadata providers to create a comprehensive joint catalogue to help researchers find interesting data objects and collections.
DBpedia is a crowd-sourced community effort to extract structured information from Wikipedia and make this information available on the Web. DBpedia allows you to ask sophisticated queries against Wikipedia, and to link the different data sets on the Web to Wikipedia data. We hope that this work will make it easier for the huge amount of information in Wikipedia to be used in some new interesting ways. Furthermore, it might inspire new mechanisms for navigating, linking, and improving the encyclopedia itself.
Merritt is a curation repository for the preservation of and access to the digital research data of the ten campus University of California system and external project collaborators. Merritt is supported by the University of California Curation Center (UC3) at the California Digital Library (CDL). While Merritt itself is content agnostic, accepting digital content regardless of domain, format, or structure, it is being used for management of research data, and it forms the basis for a number of domain-specific repositories, such as the ONEShare repository for earth and environmental science and the DataShare repository for life sciences. Merritt provides persistent identifiers, storage replication, fixity audit, complete version history, REST API, a comprehensive metadata catalog for discovery, ATOM-based syndication, and curatorially-defined collections, access control rules, and data use agreements (DUAs). Merritt content upload and download may each be curatorially-designated as public or restricted. Merritt DOIs are provided by UC3's EZID service, which is integrated with DataCite. All DOIs and associated metadata are automatically registered with DataCite and are harvested by Ex Libris PRIMO and Thomson Reuters Data Citation Index (DCI) for high-level discovery. Merritt is also a member node in the DataONE network; curatorially-designated data submitted to Merritt are automatically registered with DataONE for additional replication and federated discovery through the ONEMercury search/browse interface.
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Rodare is the institutional research data repository at HZDR (Helmholtz-Zentrum Dresden-Rossendorf). Rodare allows HZDR researchers to upload their research software and data and enrich those with metadata to make them findable, accessible, interoperable and retrievable (FAIR). By publishing all associated research software and data via Rodare research reproducibility can be improved. Uploads receive a Digital Object Identfier (DOI) and can be harvested via a OAI-PMH interface.
Kaggle is a platform for predictive modelling and analytics competitions in which statisticians and data miners compete to produce the best models for predicting and describing the datasets uploaded by companies and users. This crowdsourcing approach relies on the fact that there are countless strategies that can be applied to any predictive modelling task and it is impossible to know beforehand which technique or analyst will be most effective.
The German Text Archive (Deutsches Textarchiv, DTA) presents online a selection of key German-language works in various disciplines from the 17th to 19th centuries. The electronic full-texts are indexed linguistically and the search facilities tolerate a range of spelling variants. The DTA presents German-language printed works from around 1650 to 1900 as full text and as digital facsimile. The selection of texts was made on the basis of lexicographical criteria and includes scientific or scholarly texts, texts from everyday life, and literary works. The digitalisation was made from the first edition of each work. Using the digital images of these editions, the text was first typed up manually twice (‘double keying’). To represent the structure of the text, the electronic full-text was encoded in conformity with the XML standard TEI P5. The next stages complete the linguistic analysis, i.e. the text is tokenised, lemmatised, and the parts of speech are annotated. The DTA thus presents a linguistically analysed, historical full-text corpus, available for a range of questions in corpus linguistics. Thanks to the interdisciplinary nature of the DTA Corpus, it also offers valuable source-texts for neighbouring disciplines in the humanities, and for scientists, legal scholars and economists.
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The Goethe University Data Repository (GUDe) provides a platform for its members to electronically archive, share, and publish their research data. GUDe is jointly operated by the University Library and the University Data Center of the Goethe University. The metadata of all public content is freely available and indexed by search engines as well as scientific web services. GUDe follows the FAIR principles for long-term accessibility (minimum 10 years), allows for reliable citation via DOIs as well as cooperative access to non-public data and operates on DSpace-CRIS v7. If you have any questions regarding the use of GUDe, please consult the user documentation.
B2SHARE is a user-friendly, reliable and trustworthy way for researchers, scientific communities and citizen scientists to store and share small-scale research data from diverse contexts and disciplines. B2SHARE is able to add value to your research data via (domain tailored) metadata, and assigning citable Persistent Identifiers PIDs (Handles) to ensure long-lasting access and references. B2SHARE is one of the B2 services developed via EUDAT and long tail data deposits do not cost money. Special arrangements such as branding and special metadata elements can be made on request.
The European Nucleotide Archive (ENA) captures and presents information relating to experimental workflows that are based around nucleotide sequencing. A typical workflow includes the isolation and preparation of material for sequencing, a run of a sequencing machine in which sequencing data are produced and a subsequent bioinformatic analysis pipeline. ENA records this information in a data model that covers input information (sample, experimental setup, machine configuration), output machine data (sequence traces, reads and quality scores) and interpreted information (assembly, mapping, functional annotation). Data arrive at ENA from a variety of sources. These include submissions of raw data, assembled sequences and annotation from small-scale sequencing efforts, data provision from the major European sequencing centres and routine and comprehensive exchange with our partners in the International Nucleotide Sequence Database Collaboration (INSDC). Provision of nucleotide sequence data to ENA or its INSDC partners has become a central and mandatory step in the dissemination of research findings to the scientific community. ENA works with publishers of scientific literature and funding bodies to ensure compliance with these principles and to provide optimal submission systems and data access tools that work seamlessly with the published literature.
InnateDB is a publicly available database of the genes, proteins, experimentally-verified interactions and signaling pathways involved in the innate immune response of humans, mice and bovines to microbial infection. The database captures an improved coverage of the innate immunity interactome by integrating known interactions and pathways from major public databases together with manually-curated data into a centralised resource. The database can be mined as a knowledgebase or used with our integrated bioinformatics and visualization tools for the systems level analysis of the innate immune response.
Biological collections are replete with taxonomic, geographic, temporal, numerical, and historical information. This information is crucial for understanding and properly managing biodiversity and ecosystems, but is often difficult to access. Canadensys, operated from the Université de Montréal Biodiversity Centre, is a Canada-wide effort to unlock the biodiversity information held in biological collections.
The World Glacier Monitoring Service (WGMS) collects standardized observations on changes in mass, volume, area and length of glaciers with time (glacier fluctuations), as well as statistical information on the distribution of perennial surface ice in space (glacier inventories). Such glacier fluctuation and inventory data are high priority key variables in climate system monitoring; they form a basis for hydrological modelling with respect to possible effects of atmospheric warming, and provide fundamental information in glaciology, glacial geomorphology and quaternary geology. The highest information density is found for the Alps and Scandinavia, where long and uninterrupted records are available. As a contribution to the Global Terrestrial/Climate Observing System (GTOS, GCOS), the Division of Early Warning and Assessment and the Global Environment Outlook of UNEP, and the International Hydrological Programme of UNESCO, the WGMS collects and publishes worldwide standardized glacier data.
The National Archives of the Netherlands (Nationaal Archief), which is situated in The Hague, holds over 3.5 million records that have been created by the central government, organisations and individuals and are of national significance. Many records relate to the colonial and trading history of the Netherlands in the period from 1600 to 1975. The Dutch presence in countries in North and South America, Africa and Asia is reflected within these collections.
The GSA Data Repository is an open file in which authors of articles in our journals can place information that supplements and expands on their article. These supplements will not appear in print but may be obtained from GSA.