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Found 41 result(s)

STRING

Known and Predicted Protein-Protein Interactions

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STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations; they are derived from four sources: - Genomic Context - High-throughput Experiments - (Conserved) Coexpression - Previous Knowledge STRING quantitatively integrates interaction data from these sources for a large number of organisms, and transfers information between these organisms where applicable.

FlyReactome

a curated knowledgebase of drosophila melanogaster pathways

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<<<!!!<<< This repository is no longer available. This record is out dated >>>!!!>>>- eir fields, maintained by the FlyReactome staff.

Expression Atlas

Gene Expression Atlas

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The Expression Atlas provides information on gene expression patterns under different biological conditions such as a gene knock out, a plant treated with a compound, or in a particular organism part or cell. It includes both microarray and RNA-seq data. The data is re-analysed in-house to detect interesting expression patterns under the conditions of the original experiment. There are two components to the Expression Atlas, the Baseline Atlas and the Differential Atlas. The Baseline Atlas displays information about which gene products are present (and at what abundance) in "normal" conditions (e.g. tissue, cell type). It aims to answer questions such as "which genes are specifically expressed in human kidney?". This component of the Expression Atlas consists of highly-curated and quality-checked RNA-seq experiments from ArrayExpress. It has data for many different animal and plant species. New experiments are added as they become available. The Differential Atlas allows users to identify genes that are up- or down-regulated in a wide variety of different experimental conditions such as yeast mutants, cadmium treated plants, cystic fibrosis or the effect on gene expression of mind-body practice. Both microarray and RNA-seq experiments are included in the Differential Atlas. Experiments are selected from ArrayExpress and groups of samples are manually identified for comparison e.g. those with wild type genotype compared to those with a gene knock out. Each experiment is processed through our in-house differential expression statistical analysis pipeline to identify genes with a high probability of differential expression.

Solar and Heliospheric Observatory

SOHO

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SOHO, the Solar & Heliospheric Observatory, is a project of international collaboration between ESA and NASA to study the Sun from its deep core to the outer corona and the solar wind. SOHO was launched on December 2, 1995. The SOHO spacecraft was built in Europe by an industry team led by prime contractor Matra Marconi Space (now EADS Astrium) under overall management by ESA. The twelve instruments on board SOHO were provided by European and American scientists.

Copernicus

The European Earth Observation Pogramme

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Copernicus is a European system for monitoring the Earth. Copernicus consists of a complex set of systems which collect data from multiple sources: earth observation satellites and in situ sensors such as ground stations, airborne and sea-borne sensors. It processes these data and provides users with reliable and up-to-date information through a set of services related to environmental and security issues. The services address six thematic areas: land monitoring, marine monitoring, atmosphere monitoring, climate change, emergency management and security. The main users of Copernicus services are policymakers and public authorities who need the information to develop environmental legislation and policies or to take critical decisions in the event of an emergency, such as a natural disaster or a humanitarian crisis. Based on the Copernicus services and on the data collected through the Sentinels and the contributing missions , many value-added services can be tailored to specific public or commercial needs, resulting in new business opportunities. In fact, several economic studies have already demonstrated a huge potential for job creation, innovation and growth.

Reactome

a curated pathway database

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Reactome is a manually curated, peer-reviewed pathway database, annotated by expert biologists and cross-referenced to bioinformatics databases. Its aim is to share information in the visual representations of biological pathways in a computationally accessible format. Pathway annotations are authored by expert biologists, in collaboration with Reactome editorial staff and cross-referenced to many bioinformatics databases. These include NCBI Gene, Ensembl and UniProt databases, the UCSC and HapMap Genome Browsers, the KEGG Compound and ChEBI small molecule databases, PubMed, and Gene Ontology.

MGnify

formerly: EBI Metagenomics

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MGnify (formerly: EBI Metagenomics) offers an automated pipeline for the analysis and archiving of microbiome data to help determine the taxonomic diversity and functional & metabolic potential of environmental samples. Users can submit their own data for analysis or freely browse all of the analysed public datasets held within the repository. In addition, users can request analysis of any appropriate dataset within the European Nucleotide Archive (ENA). User-submitted or ENA-derived datasets can also be assembled on request, prior to analysis.

Ensembl Metazoa

e!EnsemblMetazoa

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Ensembl Metazoa is a genome-centric portal for metazoan species of scientific interest.

Inspire-HEP

Inspire-High Energy Physics

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CERN, DESY, Fermilab and SLAC have built the next-generation High Energy Physics (HEP) information system, INSPIRE. It combines the successful SPIRES database content, curated at DESY, Fermilab and SLAC, with the Invenio digital library technology developed at CERN. INSPIRE is run by a collaboration of CERN, DESY, Fermilab, IHEP, IN2P3 and SLAC, and interacts closely with HEP publishers, arXiv.org, NASA-ADS, PDG, HEPDATA and other information resources. INSPIRE represents a natural evolution of scholarly communication, built on successful community-based information systems, and provides a vision for information management in other fields of science.

Golm Metabolome Database

GMD

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The Golm Metabolome Database (GMD) facilitates the search for and dissemination of reference mass spectra from biologically active metabolites quantified using gas chromatography (GC) coupled to mass spectrometry (MS)

Ensembl Plants

e!EnsemblPlants

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EnsemblPlants is a genome-centric portal for plant species. Ensembl Plants is developed in coordination with other plant genomics and bioinformatics groups via the EBI's role in the transPLANT consortium.

EUREF Permanent Network

EPN

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The EPN (or EUREF Permanent Network) is a voluntary organization of several European agencies and universities that pool resources and permanent GNSS station data to generate precise GNSS products. The EPN has been created under the umbrella of the International Association Geodesy and more precisely by its sub-commission EUREF. The European Terrestrial Reference System 89 (ETRS89) is used as the standard precise GPS coordinate system throughout Europe. Supported by EuroGeographics and endorsed by the EU, this reference system forms the backbone for all geographic and geodynamic projects on the European territory both on a national as on an international level.

Copernicus Contributing Missions Online

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As part of the Copernicus Space Component programme, ESA manages the coordinated access to the data procured from the various Contributing Missions and the Sentinels, in response to the Copernicus users requirements. The Data Access Portfolio documents the data offer and the access rights per user category. The CSCDA portal is the access point to all data, including Sentinel missions, for Copernicus Core Users as defined in the EU Copernicus Programme Regulation (e.g. Copernicus Services).The Copernicus Space Component (CSC) Data Access system is the interface for accessing the Earth Observation products from the Copernicus Space Component. The system overall space capacity relies on several EO missions contributing to Copernicus, and it is continuously evolving, with new missions becoming available along time and others ending and/or being replaced.

European Research Community on Flow, Turbulence and Combustion Database - Classic Collection

ERCOFTAC Classic Collection

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This classic collection of test cases for validation of turbulence models started as an EU / ERCOFTAC project led by Pr. W. Rodi in 1995. It is maintained by Dr. T. Craft at Manchester since 1999. Initialy limited to experimental data, computational results, and results and conclusions drawn from the ERCOFTAC Workshops on Refined Turbulence Modelling (SIG15). At the moment, each case should contain at least a brief description, some data to download, and references to published work. Some cases contain significantly more information than this.

GenomeRNAi

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GenomeRNAi is a database containing phenotypes from RNA interference (RNAi) screens in Drosophila and Homo sapiens. In addition, the database provides an updated resource of RNAi reagents and their predicted quality.

BioVel

Biodiversity Virtual e-Laboratory

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<<<!!!<<< This repository is no longer available. >>>!!!>>> BioVeL is a virtual e-laboratory that supports research on biodiversity issues using large amounts of data from cross-disciplinary sources. BioVeL supports the development and use of workflows to process data. It offers the possibility to either use already made workflows or create own. BioVeL workflows are stored in MyExperiment - Biovel Group http://www.myexperiment.org/groups/643/content. They are underpinned by a range of analytical and data processing functions (generally provided as Web Services or R scripts) to support common biodiversity analysis tasks. You can find the Web Services catalogued in the BiodiversityCatalogue.

ESA Earth Online

Earth Online

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The name Earth Online derives from ESA's Earthnet programme. Earthnet prepares and attracts new ESA Earth Observation missions by setting the international cooperation scheme, preparing the basic infrastructure, building the scientific and application Community and competency in Europe to define and set-up own European Programmes in consultation with member states. Earth Online is the entry point for scientific-technical information on Earth Observation activities by the European Space Agency (ESA). The web portal provides a vast amount of content, grown and collected over more than a decade: Detailed technical information on Earth Observation (EO) missions; Satellites and sensors; EO data products & services; Online resources such as catalogues and library; Applications of satellite data; Access to promotional satellite imagery. After 10 years of operations on distinct sites, the two principal portals of ESA Earth Observation - Earth Online (earth.esa.int) and the Principal Investigator's Portal (eopi.esa.int) have moved to a new platform. ESA's technical and scientific earth observation user communities will from now on be served from a single portal, providing a modern and easy-to-use interface to our services and data.

Array Express

functional genomics data

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ArrayExpress is one of the major international repositories for high-throughput functional genomics data from both microarray and high-throughput sequencing studies, many of which are supported by peer-reviewed publications. Data sets are submitted directly to ArrayExpress and curated by a team of specialist biological curators. In the past (until 2018) datasets from the NCBI Gene Expression Omnibus database were imported on a weekly basis. Data is collected to MIAME and MINSEQE standards.

ProteomeXchange

PX

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The ProteomeXchange consortium has been set up to provide a single point of submission of MS proteomics data to the main existing proteomics repositories, and to encourage the data exchange between them for optimal data dissemination. Current members accepting submissions are: The PRIDE PRoteomics IDEntifications database at the European Bioinformatics Institute focusing mainly on shotgun mass spectrometry proteomics data PeptideAtlas/PASSEL focusing on SRM/MRM datasets.

European Nucleotide Archive

ENA

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The European Nucleotide Archive (ENA) captures and presents information relating to experimental workflows that are based around nucleotide sequencing. A typical workflow includes the isolation and preparation of material for sequencing, a run of a sequencing machine in which sequencing data are produced and a subsequent bioinformatic analysis pipeline. ENA records this information in a data model that covers input information (sample, experimental setup, machine configuration), output machine data (sequence traces, reads and quality scores) and interpreted information (assembly, mapping, functional annotation). Data arrive at ENA from a variety of sources. These include submissions of raw data, assembled sequences and annotation from small-scale sequencing efforts, data provision from the major European sequencing centres and routine and comprehensive exchange with our partners in the International Nucleotide Sequence Database Collaboration (INSDC). Provision of nucleotide sequence data to ENA or its INSDC partners has become a central and mandatory step in the dissemination of research findings to the scientific community. ENA works with publishers of scientific literature and funding bodies to ensure compliance with these principles and to provide optimal submission systems and data access tools that work seamlessly with the published literature.

CESSDA Data Catalogue

CESSDA DC

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The CESSDA Data Catalogue contains the metadata of all data in the holdings of CESSDA service providers. It is a one-stop-shop for search and discovery, enabling effective access to European research data for researchers. Details of over 40, 000 data collections are listed. These are harvested from fifteen different CESSDA Service Providers.

PANDIT

Protein and Associated Nucleotide Domains with Inferred Trees

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<<<!!!<<< Efforts to obtain renewed funding after 2008 were unfortunately not successful. PANDIT has therefore been frozen since November 2008, and its data are not updated since September 2005 when version 17.0 was released (corresponding to Pfam 17.0). The existing data and website remain available from these pages, and should remain stable and, we hope, useful. >>>!!!>>> PANDIT is a collection of multiple sequence alignments and phylogenetic trees. It contains corresponding amino acid and nucleotide sequence alignments, with trees inferred from each alignment. PANDIT is based on the Pfam database (Protein families database of alignments and HMMs), and includes the seed amino acid alignments of most families in the Pfam-A database. DNA sequences for as many members of each family as possible are extracted from the EMBL Nucleotide Sequence Database and aligned according to the amino acid alignment. PANDIT also contains a further copy of the amino acid alignments, restricted to the sequences for which DNA sequences were found.

International Ocean Discovery Program

IODP

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The International Ocean Discovery Program (IODP) is an international marine research collaboration that explores Earth's history and dynamics using ocean-going research platforms to recover data recorded in seafloor sediments and rocks and to monitor subseafloor environments. IODP depends on facilities funded by three platform providers with financial contributions from five additional partner agencies. Together, these entities represent 26 nations whose scientists are selected to staff IODP research expeditions conducted throughout the world's oceans. IODP expeditions are developed from hypothesis-driven science proposals aligned with the program's science plan Illuminating Earth's Past, Present, and Future. The science plan identifies 14 challenge questions in the four areas of climate change, deep life, planetary dynamics, and geohazards. Until 2013 under the name: International Ocean Drilling Program.

Electron Microscopy Data Bank

EMDB

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The Electron Microscopy Data Bank (EMDB) is a public repository for electron microscopy density maps of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, electron tomography, and electron (2D) crystallography.

PhytoPath

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<<<!!!<<< This site is no longer maintained and is provided for reference only. Some functionality or links may not work. For all enquiries please contact the Ensembl Helpdesk http://www.ensembl.org/Help/Contact >>>!!!>>> PhytoPath is a new bioinformatics resource that integrates genome-scale data from important plant pathogen species with literature-curated information about the phenotypes of host infection. Using the Ensembl Genomes browser, it provides access to complete genome assembly and gene models of priority crop and model-fungal, oomycete and bacterial phytopathogens. PhytoPath also links genes to disease progression using data from the curated PHI-base resource. PhytoPath portal is a joint project bringing together Ensembl Genomes with PHI-base, a community-curated resource describing the role of genes in pathogenic infection. PhytoPath provides access to genomic and phentoypic data from fungal and oomycete plant pathogens, and has enabled a considerable increase in the coverage of phytopathogen genomes in Ensembl Fungi and Ensembl Protists. PhytoPath also provides enhanced searching of the PHI-base resource as well as the fungi and protists in Ensembl Genomes.