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Found 563 result(s)
The 1000 Genomes Project is an international collaboration to produce an extensive public catalog of human genetic variation, including SNPs and structural variants, and their haplotype contexts. This resource will support genome-wide association studies and other medical research studies. The genomes of about 2500 unidentified people from about 25 populations around the world will be sequenced using next-generation sequencing technologies. The results of the study will be freely and publicly accessible to researchers worldwide. The International Genome Sample Resource (IGSR) has been established at EMBL-EBI to continue supporting data generated by the 1000 Genomes Project, supplemented with new data and new analysis.
Academic Torrents is a distributed data repository. The academic torrents network is built for researchers, by researchers. Its distributed peer-to-peer library system automatically replicates your datasets on many servers, so you don't have to worry about managing your own servers or file availability. Everyone who has data becomes a mirror for those data so the system is fault-tolerant.
AceView provides a curated, comprehensive and non-redundant sequence representation of all public mRNA sequences (mRNAs from GenBank or RefSeq, and single pass cDNA sequences from dbEST and Trace). These experimental cDNA sequences are first co-aligned on the genome then clustered into a minimal number of alternative transcript variants and grouped into genes. Using exhaustively and with high quality standards the available cDNA sequences evidences the beauty and complexity of mammals’ transcriptome, and the relative simplicity of the nematode and plant transcriptomes. Genes are classified according to their inferred coding potential; many presumably non-coding genes are discovered. Genes are named by Entrez Gene names when available, else by AceView gene names, stable from release to release. Alternative features (promoters, introns and exons, polyadenylation signals) and coding potential, including motifs, domains, and homologies are annotated in depth; tissues where expression has been observed are listed in order of representation; diseases, phenotypes, pathways, functions, localization or interactions are annotated by mining selected sources, in particular PubMed, GAD and Entrez Gene, and also by performing manual annotation, especially in the worm. In this way, both the anatomy and physiology of the experimentally cDNA supported human, mouse and nematode genes are thoroughly annotated.
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The arctic data archive system (ADS) collects observation data and modeling products obtained by various Japanese research projects and gives researchers to access the results. By centrally managing a wide variety of Arctic observation data, we promote the use of data across multiple disciplines. Researchers use these integrated databases to clarify the mechanisms of environmental change in the atmosphere, ocean, land-surface and cryosphere. That ADS will be provide an opportunity of collaboration between modelers and field scientists, can be expected.
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TERN's AEKOS data portal is the original gateway to Australian ecology data. It is a ‘data and research methods’ data portal for Australia’s land-dwelling plants, animals and their environments. The primary focus of data content is raw co-located ‘species and environment’ ecological survey data that has been collected at the ‘plot’ level to describe biodiversity, its patterns and ecological processes. It is openly accessible with standard discovery metadata and user-oriented, contextual metadata critical for data reuse. Our services support the ecosystem science community, land managers and governments seeking to publish under COPE publishing ethics and the FAIR data publishing principles. AEKOS is registered with Thomson & Reuters Data Citation Index and is a recommended repository of Nature Publishing’s Scientific Data. There are currently 97,037 sites covering mostly plant biodiversity and co-located environmental data of Australia. The AEKOS initiative is supported by TERN (tern.org.au), hosted by The University of Adelaide and funded by the Australian Government’s National Research Infrastructure for Australia.
The Agricultural and Environmental Data Archive (AEDA) is the direct result of a project managed by the Freshwater Biological Association in partnership with the Centre for e-Research at King's College London, and funded by the Department for the Environment, Food & Rural Affairs (Defra). This project ran from January 2011 until December 2014 and was called the DTC Archive Project, because it was initially related to the Demonstration Test Catchments Platform developed by Defra. The archive was also designed to hold data from the GHG R&D Platform (www.ghgplatform.org.uk). After the DTC Archive Project was completed the finished archive was renamed as AEDA to reflect it's broader remit to archive data from any and all agricultural and environmental research activities.
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AgroSpace is the institutional digital repository of the University of Belgrade, Faculty of Agriculture. It provides open access to publications and other research outputs resulting from the projects implemented by the Faculty of Agriculture. The software platform of the repository is adapted to the modern standards applied in the dissemination of scientific publications and is compatible with international infrastructure in this field.
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The Alberta Food Composition Database (AFCDB) is the first comprehensive resource on food constituents, chemistry and biology dedicated to major Alberta-grown produce. It provides information on both macronutrients and micronutrients, including many of the constituents that give foods their flavor, color, taste, texture and aroma. Users can view the contents of the AFCDB from the “FoodView” (listing foods by their chemical composition) or the “ChemView” (listing chemicals by their food sources).
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ALEXA is a microarray design platform for 'alternative expression analysis'. This platform facilitates the design of expression arrays for analysis of mRNA isoforms generated from a single locus by the use of alternative transcription initiation, splicing and polyadenylation sites. We use the term 'ALEXA' to describe a collection of novel genomic methods for 'alternative expression' analysis. 'Alternative expression' refers to the identification and quantification of alternative mRNA transcripts produced by alternative transcript initiation, alternative splicing and alternative polyadenylation. This website provides supplementary materials, source code and other downloads for recent publications describing our studies of alternative expression (AE). Most recently we have developed a method, 'ALEXA-Seq' and associated resources for alternative expression analysis by massively parallel RNA sequencing.
AlgaeBase is a database of information on algae that includes terrestrial, marine and freshwater organisms. At present, the data for the marine algae, particularly seaweeds, are the most complete.
ALSoD is a freely available database that has been transformed from a single gene storage facility recording mutations in the SOD1 gene to a multigene ALS bioinformatics repository and analytical instrument combining genotype, phenotype, and geographical information with associated analysis tools. These include a comparison tool to evaluate genes side by side or jointly with user configurable features, a pathogenicity prediction tool using a combination of computational approaches to distinguish variants with nonfunctional characteristics from disease-associated mutations with more dangerous consequences, and a credibility tool to enable ALS researchers to objectively assess the evidence for gene causation in ALS. Furthermore, integration of external tools, systems for feedback, annotation by users, and two-way links to collaborators hosting complementary databases further enhance the functionality of ALSoD.
All ADNI data are shared without embargo through the LONI Image and Data Archive (IDA), a secure research data repository. Interested scientists may obtain access to ADNI imaging, clinical, genomic, and biomarker data for the purposes of scientific investigation, teaching, or planning clinical research studies. "The Alzheimer’s Disease Neuroimaging Initiative (ADNI) unites researchers with study data as they work to define the progression of Alzheimer’s disease (AD). ADNI researchers collect, validate and utilize data, including MRI and PET images, genetics, cognitive tests, CSF and blood biomarkers as predictors of the disease. Study resources and data from the North American ADNI study are available through this website, including Alzheimer’s disease patients, mild cognitive impairment subjects, and elderly controls. "
AmeriFlux is a network of PI-managed sites measuring ecosystem CO2, water, and energy fluxes in North, Central and South America. It was established to connect research on field sites representing major climate and ecological biomes, including tundra, grasslands, savanna, crops, and conifer, deciduous, and tropical forests. As a grassroots, investigator-driven network, the AmeriFlux community has tailored instrumentation to suit each unique ecosystem. This “coalition of the willing” is diverse in its interests, use of technologies and collaborative approaches. As a result, the AmeriFlux Network continually pioneers new ground.
AmphibiaWeb is an online system enabling any user to search and retrieve information relating to amphibian biology and conservation. This site was motivated by the global declines of amphibians, the study of which has been hindered by the lack of multidisplinary studies and a lack of coordination in monitoring, in field studies, and in lab studies. We hope AmphibiaWeb will encourage a shared vision to collaboratively face the challenge of global amphibian declines and the conservation of remaining amphibians and their habitats.
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Androgen Receptor Gene Mutations Database is for all who are interested in mutations of the Androgen Receptor Gene. In light of the difficulty in getting new AR mutations published the curator will now accept new mutations that have not been published, provided that it is from a reputable research or clinical laboratory. The curator also strongly suggests that where possible, particularly in the case of new unique mutations that an attempt be made to at least confirm the pathogenicity of the putatative mutation, by showing that the mutation when transfected into a suitable expression system produces a mutant androgen receptor protein.
The database aims to bridge the gap between agent repositories and studies documenting the effect of antimicrobial combination therapies. Most notably, our primary aim is to compile data on the combination of antimicrobial agents, namely natural products such as AMP. To meet this purpose, we have developed a data curation workflow that combines text mining, manual expert curation and graph analysis and supports the reconstruction of AMP-Drug combinations.
The Australian National University undertake work to collect and publish metadata about research data held by ANU, and in the case of four discipline areas, Earth Sciences, Astronomy, Phenomics and Digital Humanities to develop pipelines and tools to enable the publication of research data using a common and repeatable approach. Aims and outcomes: To identify and describe research data held at ANU, to develop a consistent approach to the publication of metadata on the University's data holdings: Identification and curation of significant orphan data sets that might otherwise be lost or inadvertently destroyed, to develop a culture of data data sharing and data re-use.
Apollo (previously DSpace@Cambridge) is the University of Cambridge’s Institutional Repository (IR), preserving and providing access to content created by members of the University. The repository stores a range of content and provides different levels of access, but its primary focus is on providing open access to the University’s research publications.
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SeSam is an outstanding international collection of recent and fossil animals and plants from all over the world. It also holds an important specialized library. The really substantial data of this collection constitute the basis of every taxonomic-systematical, ecological, biogeographical or biostratigraphical fundamental research as well as every practical environmental research. Because of its historical referencings this collection is also a precious cultural treasure that generates the often expensive heavy mission of its conservation. The new system is called AQUiLA.
Arca Data is Fiocruz's official repository for archiving, publishing, disseminating, preserving and sharing digital research data produced by the Fiocruz community or in partnership with other research institutes or bodies, with the aim of promoting new research, ensuring the reproducibility or replicability of existing research and promoting an Open and Citizen Science. Its objective is to stimulate the wide circulation of scientific knowledge, strengthening the institutional commitment to Open Science and free access to health information, in addition to providing transparency and fostering collaboration between researchers, educators, academics, managers and graduate students, to the advancement of knowledge and the creation of solutions that meet the demands of society.
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Arquivo.pt is a research infrastructure that preserves millions of files collected from the web since 1996 and provides a public search service over this information. It contains information in several languages. Periodically it collects and stores information published on the web. Then, it processes the collect data to make it searchable, providing a “Google-like” service that enables searching the past web (English user interface available at https://arquivo.pt/?l=en). This preservation workflow is performed through a large-scale distributed information system and can also accessed through API (https://arquivo.pt/api).
ASAP (a systematic annotation package for community analysis of genomes) is a relational database and web interface developed to store, update and distribute genome sequence data and gene expression data collected by or in collaboration with researchers at the University of Wisconsin - Madison. ASAP was designed to facilitate ongoing community annotation of genomes and to grow with genome projects as they move from the preliminary data stage through post-sequencing functional analysis. The ASAP database includes multiple genome sequences at various stages of analysis, and gene expression data from preliminary experiments.
The ASEP Data Repository is an institutional multidisciplinary on-line repository that stores scientific outputs - bibliographic records, full texts and datasets of the institutional authors from The Czech Academy of Sciences. The repository is hosted by Library of the Czech Academy of Sciences. Data that are stored in database are accessible in the on-line catalogue. Each dataset has its own description and metadata according to international standards.