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Found 78 result(s)

Project Achilles

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Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to silence or knock-out individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines provides a complementary approach to those studies that aim to characterize the molecular alterations (e.g. mutations, copy number alterations) of primary tumors, such as The Cancer Genome Atlas (TCGA). The overall goal of the project is to identify cancer genetic dependencies and link them to molecular characteristics in order to prioritize targets for therapeutic development and identify the patient population that might benefit from such targets. Project Achilles data is hosted on the Cancer Dependency Map Portal (DepMap) where it has been harmonized with our genomics and cellular models data. You can access the latest and all past datasets here: https://depmap.org/portal/download/all/

ASAP

A systematic annotation package for community analysis of genomes

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ASAP (a systematic annotation package for community analysis of genomes) is a relational database and web interface developed to store, update and distribute genome sequence data and gene expression data collected by or in collaboration with researchers at the University of Wisconsin - Madison. ASAP was designed to facilitate ongoing community annotation of genomes and to grow with genome projects as they move from the preliminary data stage through post-sequencing functional analysis. The ASAP database includes multiple genome sequences at various stages of analysis, and gene expression data from preliminary experiments.

Fungal Genetics Stock Center

FGSC

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The Fungal Genetics Stock Center has preserved and distributed strains of genetically characterized fungi since 1960. The collection includes over 20,000 accessioned strains of classical and genetically engineered mutants of key model, human, and plant pathogenic fungi. These materials are distributed as living stocks to researchers around the world.

Earth System Grid Federation

ESGF

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The Earth System Grid Federation (ESGF) is an international collaboration with a current focus on serving the World Climate Research Programme's (WCRP) Coupled Model Intercomparison Project (CMIP) and supporting climate and environmental science in general. Data is searchable and available for download at the Federated ESGF-CoG Nodes https://esgf.llnl.gov/nodes.html

Cancer Genomics Hub

CGHub

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>>>>!!!!<<<< The Cancer Genomics Hub mission is now completed. The Cancer Genomics Hub was established in August 2011 to provide a repository to The Cancer Genome Atlas, the childhood cancer initiative Therapeutically Applicable Research to Generate Effective Treatments and the Cancer Genome Characterization Initiative. CGHub rapidly grew to be the largest database of cancer genomes in the world, storing more than 2.5 petabytes of data and serving downloads of nearly 3 petabytes per month. As the central repository for the foundational genome files, CGHub streamlined team science efforts as data became as easy to obtain as downloading from a hard drive. The convenient access to Big Data, and the collaborations that CGHub made possible, are now essential to cancer research. That work continues at the NCI's Genomic Data Commons. All files previously stored at CGHub can be found there. The Website for the Genomic Data Commons is here: https://gdc.nci.nih.gov/ >>>>!!!!<<<< The Cancer Genomics Hub (CGHub) is a secure repository for storing, cataloging, and accessing cancer genome sequences, alignments, and mutation information from the Cancer Genome Atlas (TCGA) consortium and related projects. Access to CGHub Data: All researchers using CGHub must meet the access and use criteria established by the National Institutes of Health (NIH) to ensure the privacy, security, and integrity of participant data. CGHub also hosts some publicly available data, in particular data from the Cancer Cell Line Encyclopedia. All metadata is publicly available and the catalog of metadata and associated BAMs can be explored using the CGHub Data Browser.

FLOSSmole

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FLOSSmole is a collaborative collection of free, libre, and open source software (FLOSS) data. FLOSSmole contains nearly 1 TB of data covering the period 2004 until now, about more than 500,000 different open source projects.

Reality Commons

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Cell phones have become an important platform for the understanding of social dynamics and influence, because of their pervasiveness, sensing capabilities, and computational power. Many applications have emerged in recent years in mobile health, mobile banking, location based services, media democracy, and social movements. With these new capabilities, we can potentially be able to identify exact points and times of infection for diseases, determine who most influences us to gain weight or become healthier, know exactly how information flows among employees and productivity emerges in our work spaces, and understand how rumors spread. In an attempt to address these challenges, we release several mobile data sets here in "Reality Commons" that contain the dynamics of several communities of about 100 people each. We invite researchers to propose and submit their own applications of the data to demonstrate the scientific and business values of these data sets, suggest how to meaningfully extend these experiments to larger populations, and develop the math that fits agent-based models or systems dynamics models to larger populations. These data sets were collected with tools developed in the MIT Human Dynamics Lab and are now available as open source projects or at cost.

TheDataWeb

DataFerrett

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<<<!!!<<< This repository is no longer available. >>>!!!>>> Be advised that DataFerrett was decommissioned June 30, 2020; see https://www.census.gov/data/data-tools/dataferrett.html

GeneWeaver.org

The Ontological Discovery Environment

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GeneWeaver combines cross-species data and gene entity integration, scalable hierarchical analysis of user data with a community-built and curated data archive of gene sets and gene networks, and tools for data driven comparison of user-defined biological, behavioral and disease concepts. Gene Weaver allows users to integrate gene sets across species, tissue and experimental platform. It differs from conventional gene set over-representation analysis tools in that it allows users to evaluate intersections among all combinations of a collection of gene sets, including, but not limited to annotations to controlled vocabularies. There are numerous applications of this approach. Sets can be stored, shared and compared privately, among user defined groups of investigators, and across all users.

Research Computing and Data Services

formerly name: Northwest Knowledge Network

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NKN is now Research Computing and Data Services (RCDS)! We provide data management support for UI researchers and their regional, national, and international collaborators. This support keeps researchers at the cutting-edge of science and increases our institution's competitiveness for external research grants. Quality data and metadata developed in research projects and curated by RCDS (formerly NKN) is a valuable, long-term asset upon which to develop and build new research and science.

Qualitative Data Repository

QDR

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The Qualitative Data Repository (QDR) is a dedicated archive for storing and sharing digital data (and accompanying documentation) generated or collected through qualitative and multi-method research in the social sciences. QDR provides data management consulting services and actively curates all data projects, maintaining the value and usefulness of the data over time, and ensuring their availability and findability for re-use.

Canadian Open Neuroscience Platform Portal

CONP

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The CONP portal is a web interface for the Canadian Open Neuroscience Platform (CONP) to facilitate open science in the neuroscience community. CONP simplifies global researcher access and sharing of datasets and tools. The portal internalizes the cycle of a typical research project: starting with data acquisition, followed by processing using already existing/published tools, and ultimately publication of the obtained results including a link to the original dataset. From more information on CONP, please visit https://conp.ca

OpenTopography

A Portal to High-Resolution Topography Data and Tools

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OpenTopography facilitates community access to high-resolution, Earth science-oriented, topography data, and related tools and resources. The OpenTopography Facility is based at the San Diego Supercomputer Center at the University of California, San Diego and is operated in collaboration with colleagues in the School of Earth and Space Exploration at Arizona State University and Earthscope Consortium. Core operational support for OpenTopography comes from the National Science Foundation Earth Sciences.

Internet Archive

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The Internet Archive includes texts, audio, moving images, software, and archived web pages.

Addgene

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Addgene archives and distributes plasmids for researchers around the globe. They are working with thousands of laboratories to assemble a high-quality library of published plasmids for use in research and discovery. By linking plasmids with articles, scientists can always find data related to the materials they request.

GeoPRISMS Data Portal

Geodyanmic Processes at Rifting and Subducting Margins

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The GeoPRISMS Data Portal was established in early 2011 to serve the NSF-funded GeoPRISMS program as a dedicated data system to facilitate open and timely exchange of data in support of the interdisciplinary science goals of the program. GeoPrisms Data Portal focuses upon the coordinated, interdisciplinary investigation of the continental margins through two initiatives: the Subduction Cycles and Deformation (SCD) and Rift Initiation and Evolution (RIE). In order to address the fundamental scientific questions, each initiative is associated with Primary Sites to address a wide range of field, experimental and theoretical studies spanning broad spatial and temporal scales.

California Coastal Atlas

CCA

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The California Coastal Atlas is an experiment in the creation of a new information resource for the description, analysis and understanding of natural and human processes affecting the coast of California.

ScholarsArchive@OSU

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ScholarsArchive@OSU is Oregon State University's digital service for gathering, indexing, making available and storing the scholarly work of the Oregon State University community. It also includes materials from outside the institution in support of the university's land, sun, sea and space grant missions and other research interests.

PRO-ACT

Pooled Resource Open-Access ALS Clinical Trials Database

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The PRO-ACT platform houses the largest ALS clinical trials dataset ever created. It is a powerful tool for biomedical researchers, statisticians, clinicians, or anyone else interested in "Big Data." PRO-ACT merges data from existing public and private clinical trials, generating an invaluable resource for the design of future ALS clinical trials. The database will also contribute to the identification of unique observations, novel correlations, and patterns of ALS disease progression, as well as a variety of still unconsidered analyses. More than 600,000 people around them world are battling ALS. The disease strikes indiscriminately, and typically patients will die within 2-5 years following diagnosis. Currently, there are no effective treatments or a cure for ALS. Users of PRO-ACT are helping to accelerate the discovery, development, and delivery of ALS treatments, which will provide hope to patients and their families.

ECCAD - the GEIA database

Emissions of atmospheric Compounds & Compilation of Ancillary Data

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The main goal of the ECCAD project is to provide scientific and policy users with datasets of surface emissions of atmospheric compounds, and ancillary data, i.e. data required to estimate or quantify surface emissions. The supply of ancillary data - such as maps of population density, maps of fires spots, burnt areas, land cover - could help improve and encourage the development of new emissions datasets. ECCAD offers: Access to global and regional emission inventories and ancillary data, in a standardized format Quick visualization of emission and ancillary data Rationalization of the use of input data in algorithms or emission models Analysis and comparison of emissions datasets and ancillary data Tools for the evaluation of emissions and ancillary data ECCAD is a dynamical and interactive database, providing the most up to date datasets including data used within ongoing projects. Users are welcome to add their own datasets, or have their regional masks included in order to use ECCAD tools.

Minnesota Population Center

MPC

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The Minnesota Population Center (MPC) is a University-wide interdisciplinary cooperative for demographic research. The MPC serves more than 80 faculty members and research scientists from eight colleges and institutes at the University of Minnesota. As a leading developer and disseminator of demographic data, we also serve a broader audience of some 50,000 demographic researchers worldwide. MPC is a DataONE member node: https://search.dataone.org/#profile/US_MPC

KNB Data Repository

Knowledge Network for Biocomplexity

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The KNB Data Repository is an international repository intended to facilitate ecological, environmental and earth science research in the broadest senses. For scientists, the KNB Data Repository is an efficient way to share, discover, access and interpret complex ecological, environmental, earth science, and sociological data and the software used to create and manage those data. Due to rich contextual information provided with data in the KNB, scientists are able to integrate and analyze data with less effort. The data originate from a highly-distributed set of field stations, laboratories, research sites, and individual researchers. The KNB supports rich, detailed metadata to promote data discovery as well as automated and manual integration of data into new projects. The KNB supports a rich set of modern repository services, including the ability to assign Digital Object Identifiers (DOIs) so data sets can be confidently referenced in any publication, the ability to track the versions of datasets as they evolve through time, and metadata to establish the provenance relationships between source and derived data.

REasons for Geographic and Racial Differences in Stroke Study

REGARDS

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REGARDS is an observational study of risk factors for stroke in adults 45 years or older. 30,239 participants were recruited between January 2003 and October 2007. They completed a telephone interview followed by an in-home physical exam. Measurements included traditional risk factors such as blood pressure and cholesterol levels, and an echocardiogram of the heart. At six month intervals, participants are contacted by phone to ask about stroke symptoms, hospitalizations and general health status. The study is ongoing and will follow participants for many years.

St. Edward's University institutional repository

St. Edward’s University Figshare

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Additionally to the institutional repository, current St. Edward's faculty have the option of uploading their work directly to their own SEU accounts on stedwards.figshare.com. Projects created on Figshare will automatically be published on this website as well. For more information, please see documentation

Nuclear Data Services

NDS

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Nuclear Data Services contains atomic, molecular and nuclear data sets for the development and maintenance of nuclear technologies. It includes energy-dependent reaction probabilities (cross sections), the energy and angular distributions of reaction products for many combinations of target and projectile, and the atomic and nuclear properties of excited states, and their radioactive decay data. Their main concern is providing data required to design a modern nuclear reactor for electricity production. Approximately 11.5 million nuclear data points have been measured and compiled into computerized form.