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Found 12 result(s)
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<<<!!!<<< This repository is no longer available. >>>!!!>>> A human interactome map. The sequencing of the human genome has provided a surprisingly small number of genes, indicating that the complex organization of life is not reflected in the gene number but, rather, in the gene products – that is, in the proteins. These macromolecules regulate the vast majority of cellular processes by their ability to communicate with each other and to assemble into larger functional units. Therefore, the systematic analysis of protein-protein interactions is fundamental for the understanding of protein function, cellular processes and, ultimately, the complexity of life. Moreover, interactome maps are particularly needed to link new proteins to disease pathways and the identification of novel drug targets.
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GEOFON seeks to facilitate cooperation in seismological research and earthquake and tsunami hazard mitigation by providing rapid transnational access to seismological data and source parameters of large earthquakes, and keeping these data accessible in the long term. It pursues these aims by operating and maintaining a global network of permanent broadband stations in cooperation with local partners, facilitating real time access to data from this network and those of many partner networks and plate boundary observatories, providing a permanent and secure archive for seismological data. It also archives and makes accessible data from temporary experiments carried out by scientists at German universities and institutions, thereby fostering cooperation and encouraging the full exploitation of all acquired data and serving as the permanent archive for the Geophysical Instrument Pool at Potsdam (GIPP). It also organises the data exchange of real-time and archived data with partner institutions and international centres.
The Bavarian Natural History Collections (Staatliche Naturwissenschaftliche Sammlungen Bayerns, SNSB) are a research institution for natural history in Bavaria. They encompass five State Collections (zoology, botany, paleontology and geology, mineralogy, anthropology and paleoanatomy), the Botanical Garden Munich-Nymphenburg and eight museums with public exhibitions in Munich, Bamberg, Bayreuth, Eichstätt and Nördlingen. Our research focuses mainly on the past and present bio- and geodiversity and the evolution of animals and plants. To achieve this we have large scientific collections (almost 35,000,000 specimens), see "joint projects".
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<<<!!!<<< This repository is no longer available. >>>!!!>>> The main objective of our work is to understand the pathomechanisms of late onset neurodegenerative disorders such as Huntington's, Parkinson's, Alzheimer's and Machado Joseph disease and to develop causal therapies for them. The disease causing proteins of these illnesses have been identified, but their functions in the unaffected organism are mostly unknown. Here, we have developed a strategy combining library and matrix yeast two-hybrid screens to generate a highly connected PPI network for Huntington's disease (HD).
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GEOMAR Helmholtz Centre for Ocean Research Kiel is one of the leading marine science institutions in Europe. GEOMAR investigates the chemical, physical, biological, and geological processes in the oceans, as well as their interactions with the seafloor and the atmosphere. OceanRep is an open access digital collection containing the research output of GEOMAR staff and students. Included are journal articles, conference papers, book chapters, theses and more, - with fulltext, if available. Research data are linked to the publications entries.
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With its “Blood Donor BIOBANK”, the Bavarian Red Cross (BRK) Blood Donor Service offers a unique and innovative resource for biomarker research: the world’s first blood donor based biobank. Biobanks as collections of biological material together with associated medical data open new possibilities for the development of new targeted diagnostics and therapies. The BRK Blood Donor Service maintains a unique collection of over 3 million blood samples, making it one of the largest sample collections worldwide. Every working day 2,000 new samples are added to the collection.
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The Research Data Repository of FID move is a digital long-term repository for open data from the field of transport and mobility research. All datasets are provided with an open licence and are assigned a persistent DataCite DOI (Digital Object Identifier). Both data search and archiving are free. The Specialised Information Service for Mobility and Transport Research (FID move) has been set up by the Saxon State and University Library Dresden (SLUB) and the German TIB – Leibniz Information Centre for Science and Technology as part of the DFG funding programme "Specialised Information Services".
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Supported by the DFG, the project „MO|RE data“ assembles a public eResearch-Infrastructure for motor research data until 2016. It focuses on selected standardized motor tests of wide acceptance. Furthermore MO|RE data generates quality authority control and publishes accompanying material for motor tests.
The DARIAH-DE repository is a digital long-term archive for human and cultural-scientific research data. Each object described and stored in the DARIAH-DE Repository has a unique and lasting Persistent Identifier (DOI), with which it is permanently referenced, cited, and kept available for the long term. In addition, the DARIAH-DE Repository enables the sustainable and secure archiving of data collections. The DARIAH-DE Repository is not only to DARIAH-DE associated research projects, but also to individual researchers as well as research projects that want to save their research data persistently, referenceable and long-term archived and make it available to third parties. The main focus is the simple and user-oriented access to long-term storage of research data. To ensure its long term sustainability, the DARIAH-DE Repository is operated by the Humanities Data Centre.
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The Jülich Observatory for Cloud Evolution (JOYCE) operates ground-based active and passive remote sensing instruments for cloud and precipitation observations. ​JOYCE is based on a long-term successful collaboration between the University of Cologne, the University of Bonn and the Research Centre Jülich. Since 2017 JOYCE is transformed into a Core Facility (JOYCE - CF) funded by the DFG (Deutsche Forschungsgemeinschaft) with the aim of high quality radar and passive microwave observations of the atmosphere. JOYCE will serve as a reference center for best practices in data acquisition, storage and distribution. JOYCE instrumentation aims to observe spatial and temporal variability of atmospheric water cycle variables.
The GTN-P database is an object-related database open for a diverse range of data. Because of the complexity of the PAGE21 project, data provided in the GTN-P management system are extremely diverse, ranging from active-layer thickness measurements once per year to flux measurement every second and everthing else in between. The data can be assigned to two broad categories: Quantitative data which is all data that can be measured numerically. Quantitative data comprise all in situ measurements, i.e. permafrost temperatures and active layer thickness (mechanical probing, frost/thaw tubes, soil temperature profiles). Qualitative data (knowledge products) are observations not based on measurements, such as observations on soils, vegetation, relief, etc.