Huntingtin Interaction Network

Name of repository

Huntingtin Interaction Network

Repository URL

http://artemis.mdc-berlin.de/huntington/eingabe.php

Subject(s)

• Life Sciences
• Biology
• Basic Research in Biology and Medicine
• Bioinformatics and Theoretical Biology

Description

<<<!!!<<< This repository is no longer available. >>>!!!>>> The main objective of our work is to understand the pathomechanisms of late onset neurodegenerative disorders such as Huntington's, Parkinson's, Alzheimer's and Machado Joseph disease and to develop causal therapies for them. The disease causing proteins of these illnesses have been identified, but their functions in the unaffected organism are mostly unknown. Here, we have developed a strategy combining library and matrix yeast two-hybrid screens to generate a highly connected PPI network for Huntington's disease (HD).

Contact(s)

• administrative: silvio.schwartz@mdc-berlin.de
• administrative: https://www.mdc-berlin.de/40599278/en/globals/Contact

Keyword(s)

• COS cells
• Huntington
• RNA
• antibodies
• max-delbrueck
• mdc
• neurogenerative disorder
• neuroproteomics
• phosphoproteins
• protein
• protein binding
• protein-protein interaction
• proteomics
• signaltransducing
• two-hybrid system techniques

Repository type(s)

• disciplinary

Mission statement for designated community

https://www.mdc-berlin.de/1157755/en/research/research_teams/proteomics_and_molecular_mechanisms_of_neurodegenerative_diseases

Research data repository language(s)

• English

Data and/or service provider

• dataProvider