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The Protein Data Bank (PDB) is an archive of experimentally determined three-dimensional structures of biological macromolecules that serves a global community of researchers, educators, and students. The data contained in the archive include atomic coordinates, crystallographic structure factors and NMR experimental data. Aside from coordinates, each deposition also includes the names of molecules, primary and secondary structure information, sequence database references, where appropriate, and ligand and biological assembly information, details about data collection and structure solution, and bibliographic citations. The Worldwide Protein Data Bank (wwPDB) consists of organizations that act as deposition, data processing and distribution centers for PDB data. Members are: RCSB PDB (USA), PDBe (Europe) and PDBj (Japan), and BMRB (USA). The wwPDB's mission is to maintain a single PDB archive of macromolecular structural data that is freely and publicly available to the global community.
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CRAN is a network of ftp and web servers around the world that store identical, up-to-date, versions of code and documentation for R. R is ‘GNU S’, a freely available language and environment for statistical computing and graphics which provides a wide variety of statistical and graphical techniques: linear and nonlinear modelling, statistical tests, time series analysis, classification, clustering, etc. Please consult the R project homepage for further information.
ArrayExpress is one of the major international repositories for high-throughput functional genomics data from both microarray and high-throughput sequencing studies, many of which are supported by peer-reviewed publications. Data sets are submitted directly to ArrayExpress and curated by a team of specialist biological curators. In the past (until 2018) datasets from the NCBI Gene Expression Omnibus database were imported on a weekly basis. Data is collected to MIAME and MINSEQE standards.
The Electron Microscopy Data Bank (EMDB) is a public repository for electron microscopy density maps of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, electron tomography, and electron (2D) crystallography.
This site provides access to complete, annotated genomes from bacteria and archaea (present in the European Nucleotide Archive) through the Ensembl graphical user interface (genome browser). Ensembl Bacteria contains genomes from annotated INSDC records that are loaded into Ensembl multi-species databases, using the INSDC annotation import pipeline.
The datacommons@psu was developed in 2005 to provide a resource for data sharing, discovery, and archiving for the Penn State research and teaching community. Access to information is vital to the research, teaching, and outreach conducted at Penn State. The datacommons@psu serves as a data discovery tool, a data archive for research data created by PSU for projects funded by agencies like the National Science Foundation, as well as a portal to data, applications, and resources throughout the university. The datacommons@psu facilitates interdisciplinary cooperation and collaboration by connecting people and resources and by: - Acquiring, storing, documenting, and providing discovery tools for Penn State based research data, final reports, instruments, models and applications. - Highlighting existing resources developed or housed by Penn State. - Supporting access to project/program partners via collaborative map or web services. - Providing metadata development citation information, Digital Object Identifiers (DOIs) and links to related publications and project websites. Members of the Penn State research community and their affiliates can easily share and house their data through the datacommons@psu. The datacommons@psu will also develop metadata for your data and provide information to support your NSF, NIH, or other agency data management plan.
The Sequence Read Archive stores the raw sequencing data from such sequencing platforms as the Roche 454 GS System, the Illumina Genome Analyzer, the Applied Biosystems SOLiD System, the Helicos Heliscope, and the Complete Genomics. It archives the sequencing data associated with RNA-Seq, ChIP-Seq, Genomic and Transcriptomic assemblies, and 16S ribosomal RNA data.
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The National Cryosphere Desert Data Center (hereinafter referred to as NCDC) is supported by the Institute of environment and Engineering in the cold and dry areas of the Chinese Academy of Sciences, in cooperation with Xinjiang Institute of ecology and geography of the Chinese Academy of Sciences, Chengdu Institute of mountain land disaster and environment of the Ministry of water resources of the Chinese Academy of Sciences, Qinghai Salt Lake Research Institute of the Chinese Academy of Sciences and Qinghai Gao of the Chinese Academy of Sciences The Institute of protobiology and other units were jointly established. The supporting units of glacier permafrost desert data center have formed a scientific research and support system of seven research laboratories and three research systems, highlighting the research characteristics of glacier, permafrost, desert, atmosphere, water and soil, ecology, environment, resources, engineering and sustainable development in the dry areas of cold regions.
Hourly "Near-Earth" solar wind magnetic field and plasma data, energetic proton fluxes (>1 to >60 MeV), and geomagnetic and solar activity indices. OMNIWeb is part of "Space Physics Data Facility" (https://www.re3data.org/repository/r3d100010168 ).
With the creation of the Metabolomics Data Repository managed by Data Repository and Coordination Center (DRCC), the NIH acknowledges the importance of data sharing for metabolomics. Metabolomics represents the systematic study of low molecular weight molecules found in a biological sample, providing a "snapshot" of the current and actual state of the cell or organism at a specific point in time. Thus, the metabolome represents the functional activity of biological systems. As with other ‘omics’, metabolites are conserved across animals, plants and microbial species, facilitating the extrapolation of research findings in laboratory animals to humans. Common technologies for measuring the metabolome include mass spectrometry (MS) and nuclear magnetic resonance spectroscopy (NMR), which can measure hundreds to thousands of unique chemical entities. Data sharing in metabolomics will include primary raw data and the biological and analytical meta-data necessary to interpret these data. Through cooperation between investigators, metabolomics laboratories and data coordinating centers, these data sets should provide a rich resource for the research community to enhance preclinical, clinical and translational research.
Modern signal processing and machine learning methods have exciting potential to generate new knowledge that will impact both physiological understanding and clinical care. Access to data - particularly detailed clinical data - is often a bottleneck to progress. The overarching goal of PhysioNet is to accelerate research progress by freely providing rich archives of clinical and physiological data for analysis. The PhysioNet resource has three closely interdependent components: An extensive archive ("PhysioBank"), a large and growing library of software ("PhysioToolkit"), and a collection of popular tutorials and educational materials
The UCI Machine Learning Repository is a collection of databases, domain theories, and data generators that are used by the machine learning community for the empirical analysis of machine learning algorithms. It is used by students, educators, and researchers all over the world as a primary source of machine learning data sets. As an indication of the impact of the archive, it has been cited over 1000 times.
The BioImage Archive stores and distributes life sciences imaging datasets. It supports deposition of biological imaging data associated with publications for the whole research community, as well as reference imaging datasets. All data deposited to the BioImage Archive is made openly accessible to the scientific community.
<<<!!!<<< The demand for high-value environmental data and information has dramatically increased in recent years. To improve our ability to meet that demand, NOAA’s former three data centers—the National Climatic Data Center, the National Geophysical Data Center, and the National Oceanographic Data Center, which includes the National Coastal Data Development Center—have merged into the National Centers for Environmental Information (NCEI). >>>!!!>>> NCEI is responsible for hosting and providing access to one of the most significant archives on Earth, with comprehensive oceanic, atmospheric, and geophysical data. From the depths of the ocean to the surface of the sun and from million-year-old sediment records to near real-time satellite images, NCEI is the Nation's leading authority for environmental information. The National Centers for Environmental Information (NCEI), which hosts the World Data Service for Oceanography is a national environmental data center operated by the National Oceanic and Atmospheric Administration (NOAA) of the U.S. Department of Commerce. NCEI are responsible for hosting and providing access to one of the most significant archives on earth, with comprehensive oceanic, atmospheric, and geophysical data. The primary mission of the World Data Service for Oceanography is to ensure that global oceanographic datasets collected at great cost are maintained in a permanent archive that is easily and openly accessible to the world science community and to other users.
<<<!!!<<< The demand for high-value environmental data and information has dramatically increased in recent years. To improve our ability to meet that demand, NOAA’s former three data centers—the National Climatic Data Center, the National Geophysical Data Center, and the National Oceanographic Data Center, which includes the National Coastal Data Development Center—have merged into the National Centers for Environmental Information (NCEI). >>>!!!>>> The National Oceanographic Data Center includes the National Coastal Data Development Center (NCDDC) and the NOAA Central Library, which are integrated to provide access to the world's most comprehensive sources of marine environmental data and information. NODC maintains and updates a national ocean archive with environmental data acquired from domestic and foreign activities and produces products and research from these data which help monitor global environmental changes. These data include physical, biological and chemical measurements derived from in situ oceanographic observations, satellite remote sensing of the oceans, and ocean model simulations.
The NASA Space Science Data Coordinated Archive serves as the permanent archive for NASA space science mission data. "Space science" means astronomy and astrophysics, solar and space plasma physics, and planetary and lunar science. As permanent archive, NSSDCA teams with NASA's discipline-specific space science "active archives" which provide access to data to researchers and, in some cases, to the general public. NSSDCA also serves as NASA's permanent archive for space physics mission data. It provides access to several geophysical models and to data from some non-NASA mission data. In addition to supporting active space physics and astrophysics researchers, NSSDCA also supports the general public both via several public-interest web-based services (e.g., the Photo Gallery) and via the offline mailing of CD-ROMs, photoprints, and other items.
The United States Census Bureau (officially the Bureau of the Census, as defined in Title 13 U.S.C. § 11) is the government agency that is responsible for the United States Census. It also gathers other national demographic and economic data. As a part of the United States Department of Commerce, the Census Bureau serves as a leading source of data about America's people and economy. The most visible role of the Census Bureau is to perform the official decennial (every 10 years) count of people living in the U.S. The most important result is the reallocation of the number of seats each state is allowed in the House of Representatives, but the results also affect a range of government programs received by each state. The agency director is a political appointee selected by the President of the United States.
The NCBI Nucleotide database collects sequences from such sources as GenBank, RefSeq, TPA, and PDB. Sequences collected relate to genome, gene, and transcript sequence data, and provide a foundation for research related to the biomedical field.
MetaboLights is a database for Metabolomics experiments and derived information. The database is cross-species, cross-technique and covers metabolite structures and their reference spectra as well as their biological roles, locations and concentrations, and experimental data from metabolic experiments.
The Ensembl genome annotation system, developed jointly by the EBI and the Wellcome Trust Sanger Institute, has been used for the annotation, analysis and display of vertebrate genomes since 2000. Since 2009, the Ensembl site has been complemented by the creation of five new sites, for bacteria, protists, fungi, plants and invertebrate metazoa, enabling users to use a single collection of (interactive and programatic) interfaces for accessing and comparing genome-scale data from species of scientific interest from across the taxonomy. In each domain, we aim to bring the integrative power of Ensembl tools for comparative analysis, data mining and visualisation across genomes of scientific interest, working in collaboration with scientific communities to improve and deepen genome annotation and interpretation.
It is an interactive website offering access to genome sequence data from a variety of vertebrate and invertebrate species and major model organisms, integrated with a large collection of aligned annotations. The Browser is a graphical viewer optimized to support fast interactive performance and is an open-source, web-based tool suite built on top of a MySQL database for rapid visualization, examination, and querying of the data at many levels.
The BioProject database is a searcheable collection of complete and incomplete (in-progress) large-scale molecular projects including genome sequencing and assembly, transcriptome, metagenomic, annotation, expression and mapping projects. BioProject provides a central point to link to all data associated with a project in the NCBI molecular and literature databases.
The PRIDE PRoteomics IDEntifications database is a centralized, standards compliant, public data repository for proteomics data, including protein and peptide identifications, post-translational modifications and supporting spectral evidence. PRIDE encourages and welcomes direct user submissions of mass spectrometry data to be published in peer-reviewed publications.
IRIS offers free and open access to a comprehensive data store of raw geophysical time-series data collected from a large variety of sensors, courtesy of a vast array of US and International scientific networks, including seismometers (permanent and temporary), tilt and strain meters, infrasound, temperature, atmospheric pressure and gravimeters, to support basic research aimed at imaging the Earth's interior. IRIS has merged with UNAVCO to form EarthScope Consortium! https://www.earthscope.org/about/earthscope/