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Found 25 result(s)
The HUGO Gene Nomenclature Committee (HGNC) assigned unique gene symbols and names to over 35,000 human loci, of which around 19,000 are protein coding. This curated online repository of HGNC-approved gene nomenclature and associated resources includes links to genomic, proteomic and phenotypic information, as well as dedicated gene family pages.
Gramene is a platform for comparative genomic analysis of agriculturally important grasses, including maize, rice, sorghum, wheat and barley. Relationships between cereals are queried and displayed using controlled vocabularies (Gene, Plant, Trait, Environment, and Gramene Taxonomy) and web-based displays, including the Genes and Quantitative Trait Loci (QTL) modules.
The UniProt Knowledgebase (UniProtKB) is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation. In addition to capturing the core data mandatory for each UniProtKB entry (mainly, the amino acid sequence, protein name or description, taxonomic data and citation information), as much annotation information as possible is added. This includes widely accepted biological ontologies, classifications and cross-references, and clear indications of the quality of annotation in the form of evidence attribution of experimental and computational data. The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc). The UniProt Metagenomic and Environmental Sequences (UniMES) database is a repository specifically developed for metagenomic and environmental data. The UniProt Knowledgebase,is an expertly and richly curated protein database, consisting of two sections called UniProtKB/Swiss-Prot and UniProtKB/TrEMBL.
Launched in 2000, WormBase is an international consortium of biologists and computer scientists dedicated to providing the research community with accurate, current, accessible information concerning the genetics, genomics and biology of C. elegans and some related nematodes. In addition to their curation work, all sites have ongoing programs in bioinformatics research to develop the next generations of WormBase structure, content and accessibility
FlyBase is a database of genetic, genomic and functional data for Drosophila species, with a focus on the model organism Drosophila melanogaster.FlyBase contains a complete annotation of the Drosophila melanogaster genome that is updated several times per year.It also includes a searchable bibliography of research on Drosophila genetics in the last century. The site also provides a large database of images illustrating the full genome, and several movies detailing embryogenesis.
STOREDB is a platform for the archiving and sharing of primary data and outputs of all kinds, including epidemiological and experimental data, from research on the effects of radiation. It also provides a directory of bioresources and databases containing information and materials that investigators are willing to share. STORE supports the creation of a radiation research commons.
The UK Polar Data Centre (UK PDC) is the focal point for Arctic and Antarctic environmental data management in the UK. Part of the Natural Environmental Research Council’s (NERC) network of environmental data centres and based at the British Antarctic Survey, it coordinates the management of polar data from UK-funded research and supports researchers in complying with national and international data legislation and policy.
Established in 1965, the CSD is the world’s repository for small-molecule organic and metal-organic crystal structures. Containing the results of over one million x-ray and neutron diffraction analyses this unique database of accurate 3D structures has become an essential resource to scientists around the world. The CSD records bibliographic, chemical and crystallographic information for:organic molecules, metal-organic compounds whose 3D structures have been determined using X-ray diffraction, neutron diffraction. The CSD records results of: single crystal studies, powder diffraction studies which yield 3D atomic coordinate data for at least all non-H atoms. In some cases the CCDC is unable to obtain coordinates, and incomplete entries are archived to the CSD. The CSD includes crystal structure data arising from: publications in the open literature and Private Communications to the CSD (via direct data deposition). The CSD contains directly deposited data that are not available anywhere else, known as CSD Communications.
MicrosporidiaDB belongs to the EuPathDB family of databases and is an integrated genomic and functional genomic database for the phylum Microsporidia. In its first iteration (released in early 2010), MicrosporidiaDB contains the genomes of two Encephalitozoon species (see below). MicrosporidiaDB integrates whole genome sequence and annotation and will rapidly expand to include experimental data and environmental isolate sequences provided by community researchers. The database includes supplemental bioinformatics analyses and a web interface for data-mining.
The British Oceanographic Data Centre (BODC) is a national facility for looking after and distributing data concerning the marine environmentWe deal with biological, chemical, physical and geophysical data, and our databases contain measurements of nearly 22,000 different variables. Many of our staff have direct experience of marine data collection and analysis. They work alongside information technology specialists to ensure that data are documented and stored for current and future use.
This site provides access to complete, annotated genomes from bacteria and archaea (present in the European Nucleotide Archive) through the Ensembl graphical user interface (genome browser). Ensembl Bacteria contains genomes from annotated INSDC records that are loaded into Ensembl multi-species databases, using the INSDC annotation import pipeline.
PHI-base is a web-accessible database that catalogues experimentally verified pathogenicity, virulence and effector genes from fungal, Oomycete and bacterial pathogens, which infect animal, plant, fungal and insect hosts. PHI-base is therfore an invaluable resource in the discovery of genes in medically and agronomically important pathogens, which may be potential targets for chemical intervention. In collaboration with the FRAC team, PHI-base also includes antifungal compounds and their target genes.
Until 2014 housed in the library of the Scott Polar Research Institute, the WDC for Glaciology, Cambridge, maintains a particularly comprehensive collection of publications covering all aspects of snow and ice worldwide. Glaciological literature has been systematically collected and catalogued at the Scott Polar Research Institute since 1920. The SPRI Picture Library houses one of the world's most comprehensive collections of historical photographs of the Polar Regions
The ClinicalCodes repository aims to hold code lists for all published electronic medical record studies, irrespective of code type (e.g. Read, ICD9-10, SNOMED) and database (CPRD, QResearch, THIN etc.). Once deposited, code lists will be freely available, with no login needed to download codes.
The Environmental Information Platform provides enhanced access to CEH's key data holdings via web-based tools, programming interfaces and a data catalogue. It enables you to visualise and interrogate some of the diverse environmental datasets held by CEH.
ChemSpider is a free chemical structure database providing fast access to over 58 million structures, properties and associated information. By integrating and linking compounds from more than 400 data sources, ChemSpider enables researchers to discover the most comprehensive view of freely available chemical data from a single online search. It is owned by the Royal Society of Chemistry. ChemSpider builds on the collected sources by adding additional properties, related information and links back to original data sources. ChemSpider offers text and structure searching to find compounds of interest and provides unique services to improve this data by curation and annotation and to integrate it with users’ applications.
GenBank® is a comprehensive database that contains publicly available nucleotide sequences for almost 260 000 formally described species. These sequences are obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects, including whole-genome shotgun (WGS) and environmental sampling projects. Most submissions are made using the web-based BankIt or standalone Sequin programs, and GenBank staff assigns accession numbers upon data receipt. Daily data exchange with the European Nucleotide Archive (ENA) and the DNA Data Bank of Japan (DDBJ) ensures worldwide coverage. GenBank is accessible through the NCBI Entrez retrieval system, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP.
Under the World Climate Research Programme (WCRP) the Working Group on Coupled Modelling (WGCM) established the Coupled Model Intercomparison Project (CMIP) as a standard experimental protocol for studying the output of coupled atmosphere-ocean general circulation models (AOGCMs). CMIP provides a community-based infrastructure in support of climate model diagnosis, validation, intercomparison, documentation and data access. This framework enables a diverse community of scientists to analyze GCMs in a systematic fashion, a process which serves to facilitate model improvement. Virtually the entire international climate modeling community has participated in this project since its inception in 1995. The Program for Climate Model Diagnosis and Intercomparison (PCMDI) archives much of the CMIP data and provides other support for CMIP. We are now beginning the process towards the IPCC Fifth Assessment Report and with it the CMIP5 intercomparison activity. The CMIP5 (CMIP Phase 5) experiment design has been finalized with the following suites of experiments: I Decadal Hindcasts and Predictions simulations, II "long-term" simulations, III "atmosphere-only" (prescribed SST) simulations for especially computationally-demanding models. The new ESGF peer-to-peer (P2P) enterprise system (http://pcmdi9.llnl.gov) is now the official site for CMIP5 model output. The old gateway (http://pcmdi3.llnl.gov) is deprecated and now shut down permanently.
<<<!!!<<< This repository is no longer available. SPECTRa (Submission, Preservation and Exposure of Chemistry Teaching and Research Data) was a collaboration between Cambridge University and Imperial College to research issues in the deposition of chemistry data in Open Access digital repositories. Funded by the JISC (Joint Information Systems Committee) under its Digital Repositories programme, it ran from October 2005 to March 2007. Requirements for and attitudes towards data archiving and open access publication were discovered by interview and survey. This led to the development of a set of Open Source software tools for packaging and submitting X-ray crystallography, NMR spectra and computational chemistry data to DSpace digital repositories. This collection will hold reports, presentations and papers published from the project: https://www.repository.cam.ac.uk/handle/1810/183858 >>>!!!>>>
British Antarctic Survey (BAS) has, for over 60 years, undertaken the majority of Britain's scientific research on and around the Antarctic continent. Atmospheric, biosphere, cryosphere, geosphere, hydrosphere, and Sun-Earth interactions metadata and data are available. Geographic information and collections are highlighted as well. Information and mapping services include a Discovery Metadata System, Data Access System, the Antarctic Digital Database (ADD), Geophysics Data Portal (BAS-GDP), ICEMAR, a fossil database, and the Antarctic Plant Database.
The UK Data Service is a national data service funded by the ESRC to provide research access to the UK’s largest collection of social, economic and population data including UK government-sponsored surveys, cross-national surveys, longitudinal studies, UK census data, international aggregate, business data, and qualitative data. Designed to meet the data needs of researchers, students and teachers from all sectors, including academia, central and local government, charities and foundations, independent research centres, think tanks, business consultants and analysts, communities and the commercial sector, the UK Data Service provides access to high-quality social and economic data; support for policy-relevant research; guidance and training for the development of skills in data use, and the development of best practice in digital preservation and sharing. Data users can browse collections online and register to analyse and download them. Open Data collections are available for anyone to use. Key partners include JISC, the University of Manchester, University of Southampton, University of Leeds, University of Edinburgh and University College London (UCL). The lead partner is the UK Data Archive (https://service.re3data.org/repository/r3d100010215) based at the University of Essex, a Trusted Digital Repository (TDR) certified against the CoreTrustSeal (https://www.coretrustseal.org/) and certified against ISO27001 for Information Security (https://www.iso.org/standard/27001). The UK Data Service replaces the earlier ESRC investments of the Economic and Social Data Service (ESDS), the Secure Data Service (SDS), the Survey Question Bank and elements of the ESRC Census Programme.
The ISRCTN registry is a primary clinical trial registry recognised by WHO and ICMJE that accepts all clinical research studies (whether proposed, ongoing or completed), providing content validation and curation and the unique identification number necessary for publication. All study records in the database are freely accessible and searchable. ISRCTN supports transparency in clinical research, helps reduce selective reporting of results and ensures an unbiased and complete evidence base. ISRCTN accepts all studies involving human subjects or populations with outcome measures assessing effects on human health and well-being, including studies in healthcare, social care, education, workplace safety and economic development.