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Found 53 result(s)
SwissLipids is an expert curated resource that provides a framework for the integration of lipid and lipidomic data with biological knowledge and models.
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The Portal de datos de Biodiversidad is the biodiversity data portal of the National System of Biological Data (Sistema Nacional de Datos Biológicos, SNDB). It provides georeferenced data, published data sets, and information about biodiversity collections of the SNDB.
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ArachnoServer is a manually curated database containing information on the sequence, three-dimensional structure, and biological activity of protein toxins derived from spider venom. Spiders are the largest group of venomous animals and they are predicted to contain by far the largest number of pharmacologically active peptide toxins (Escoubas et al., 2006). ArachnoServer has been custom-built so that a wide range of biological scientists, including neuroscientists, pharmacologists, and toxinologists, can readily access key data relevant to their discipline without being overwhelmed by extraneous information.
ChEMBL is a database of bioactive drug-like small molecules, it contains 2-D structures, calculated properties (e.g. logP, Molecular Weight, Lipinski Parameters, etc.) and abstracted bioactivities (e.g. binding constants, pharmacology and ADMET data). The data is abstracted and curated from the primary scientific literature, and cover a significant fraction of the SAR and discovery of modern drugs We attempt to normalise the bioactivities into a uniform set of end-points and units where possible, and also to tag the links between a molecular target and a published assay with a set of varying confidence levels. Additional data on clinical progress of compounds is being integrated into ChEMBL at the current time.
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It is the objective of our motion capture database HDM05 to supply free motion capture data for research purposes. HDM05 contains more than three hours of systematically recorded and well-documented motion capture data in the C3D as well as in the ASF/AMC data format. Furthermore, HDM05 contains for more than 70 motion classes in 10 to 50 realizations executed by various actors.
The Progenetix database provides an overview of copy number abnormalities in human cancer from currently 32548 array and chromosomal Comparative Genomic Hybridization (CGH) experiments, as well as Whole Genome or Whole Exome Sequencing (WGS, WES) studies. The cancer profile data in Progenetix was curated from 1031 articles and represents 366 different cancer types, according to the International classification of Diseases in Oncology (ICD-O).
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Covalent DNA modifications have been found in numerous organisms and more are continually being discovered and characterized, as detection methods improve. Many of these modifications can affect the conformation of the DNA double helix, often resulting in downstream effects upon transcription factor binding. Some of these modifications have been demonstrated to be stable, while others are viewed as merely transient. DNAmod catalogues information on known DNA modifications, of which the well-known 5-methylcytosine is only one. It aims to profile modifications' properties, building upon data contained within the Chemical Entities of Biological Interest (ChEBI) database. It also provides literature citations and includes curated annotations on mapping techniques and natural occurrence information.
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iDog, an integrated resource for domestic dog (Canis lupus familiaris) and wild canids, provides the worldwide dog research community a variety of data services. This includes Genes, Genomes, SNPs, Breed/Disease Traits, Gene Expressions, Single Cell, Dog-Human Homolog Diseases and Literatures. In addition, iDog provides Online tools for performing genomic data visualization and analyses.
The Lens is building an open platform for Innovation Cartography. Specifically, the Lens serves nearly all of the patent documents in the world as open, annotatable digital public goods that are integrated with scholarly and technical literature along with regulatory and business data.
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NONCODE is an integrated knowledge database dedicated to non-coding RNAs (excluding tRNAs and rRNAs). Now, there are 16 species in NONCODE(human, mouse, cow, rat, chicken, fruitfly, zebrafish, celegans, yeast, Arabidopsis, chimpanzee, gorilla, orangutan, rhesus macaque, opossum and platypus).The source of NONCODE includes literature and other public databases. We searched PubMed using key words ‘ncrna’, ‘noncoding’, ‘non-coding’,‘no code’, ‘non-code’, ‘lncrna’ or ‘lincrna. We retrieved the new identified lncRNAs and their annotation from the Supplementary Material or web site of these articles. Together with the newest data from Ensembl , RefSeq, lncRNAdb and GENCODE were processed through a standard pipeline for each species.
arrayMap is a repository of cancer genome profiling data. Original) from primary repositories (e.g. NCBI GEO, EBI ArrayExpress, TCGA) is re-processed and annotated for metadata. Unique visualization of the processed data allows critical evaluation of data quality and genome information. Structured metadata provides easy access to summary statistics, with a focus on copy number aberrations in cancer entities.
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LITTERBASE summarises results from 2,046 scientific studies in understandable global maps and figures and opens scientific knowledge on marine litter to the public. In LITTERBASE, we compile information from 2,046 scientific publications on marine litter in a comprehensive data base. This forms the basis of continuously updated maps and figures for policy makers, authorities, scientists, media and the general public on the global amount, distribution and composition of marine litter and its impacts on aquatic life. The portal conveys a broad, fact-based understanding of this environmental problem.
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The goal of the Autophagy Database is to provide up-to-date relevant information including protein structure data to researchers of autophagy, and to disseminate important findings to a wider audience so that their ramifications can be appreciated. For this purpose, we strive to make the database to contain as much pertinent information as possible and to make the contents freely available in a user-friendly format.
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The National Biodiversity Information System (SNIB) of Mexico by the National Commission for the Knowledge and Use of Biodiversity (CONABIO). The SNIB is of strategic importance in a megadiversity country like Mexico, making it clear to CONABIO from the beginning that the SNIB should rely on the work of the multiplicity of institutions and national and foreign experts that for years have been dedicated to the study of biodiversity of Mexico. The creation of this system was expressed as a mandate for CONABIO in the General Law of Ecological Balance and Environmental Protection (LGEEPA Art. 80 fraction V). The participation of specialists in the generation of data and information for the SNIB is one of the various ways in which they collaborate with this system, since having an information system that allows the country to make informed decisions regarding its biodiversity requires that it be made up of data and information supported by a broad network of experts.
E-RA provides a permanent managed repository and knowledgebase for secure storage of metadata and data from Rothamsted's Long-term Experiments, the oldest, continuous agronomic experiments in the world. Together with the accompanying meteorological records, associated documentation and sample archive, it is a unique historical record of experiments that have been measured continuously since 1843. e-RA provides comprehensive descriptions of Rothamsted's long-term experiments including Broadbalk Wheat, Park Grass Hay, Hoosfield Barley, Rothamsted and Woburn Ley Arables, and Long-term Liming. e-RA maintains long-term routine data collections including crop yields, quality traits, agronomic management, soil chemistry, disease, and botanical diversity. The experiments are available as a research infrastructure to scientists and scientists are encouraged to deposit any new data generated with e-RA.
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CORUM is a manually curated dataset of mammalian protein complexes. Annotation of protein complexes includes protein complex composition and other valuable information such as method of purification, cellular function of complexes or involvement in diseases.
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Projects in the International Scientific Continental Drilling Program (ICDP) produce large amounts of data. Since the start of ICDP, data sharing has played an important part in ICDP projects, and the ICDP Operational Support Group, which provides the infrastructure for data capturing for many ICDP projects, has facilitated dissemination of data within project groups. With the online Scientific Drilling Database (SDDB; http://www.scientificdrilling.org), ICDP and GeoForschungsZentrum Potsdam (GFZ), Germany created a platform for the public dissemination of drilling data
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The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. The latest release of DrugBank (version 5.1.1, released 2018-07-03) contains 11,881 drug entries including 2,526 approved small molecule drugs, 1,184 approved biotech (protein/peptide) drugs, 129 nutraceuticals and over 5,751 experimental drugs. Additionally, 5,132 non-redundant protein (i.e. drug target/enzyme/transporter/carrier) sequences are linked to these drug entries. Each DrugCard entry contains more than 200 data fields with half of the information being devoted to drug/chemical data and the other half devoted to drug target or protein data.
The CZO Multiscale TROPIcal CatchmentS (M-TROPICS) consists in the merging, in 2016, of two previously-existing CZOs: BVET (India and Cameroon) and MSEC (Laos and Vietnam). The CZO Multiscale TROPIcal CatchmentS (M-TROPICS) provides the international scientific community with unique decennial time series of meteorological, hydrological, geochemical, and ecological variables in tropical environments. The CZO M-TROPICS involves academic and governmental partners in tropical countries (Cameroun, India, Lao PDR, and Vietnam) and is included in the Research Infrastructure OZCAR, the French contribution to the international CZO initiative.
The EUDAT project aims to contribute to the production of a Collaborative Data Infrastructure (CDI). The project´s target is to provide a pan-European solution to the challenge of data proliferation in Europe's scientific and research communities. The EUDAT vision is to support a Collaborative Data Infrastructure which will allow researchers to share data within and between communities and enable them to carry out their research effectively. EUDAT aims to provide a solution that will be affordable, trustworthy, robust, persistent and easy to use. EUDAT comprises 26 European partners, including data centres, technology providers, research communities and funding agencies from 13 countries. B2FIND is the EUDAT metadata service allowing users to discover what kind of data is stored through the B2SAFE and B2SHARE services which collect a large number of datasets from various disciplines. EUDAT will also harvest metadata from communities that have stable metadata providers to create a comprehensive joint catalogue to help researchers find interesting data objects and collections.
The UniProtKB Sequence/Annotation Version Archive (UniSave) has the mission of providing freely to the scientific community a repository containing every version of every Swiss-Prot/TrEMBL entry in the UniProt Knowledge Base (UniProtKB). This is achieved by archiving, every release, the entry versions within the current release. The primary usage of this service is to provide open access to all entry versions of all entries. In addition to viewing their content, one can also filter, download and compare versions.
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We developed a method, ChIP-sequencing (ChIP-seq), combining chromatin immunoprecipitation (ChIP) and massively parallel sequencing to identify mammalian DNA sequences bound by transcription factors in vivo. We used ChIP-seq to map STAT1 targets in interferon-gamma (IFN-gamma)-stimulated and unstimulated human HeLa S3 cells, and compared the method's performance to ChIP-PCR and to ChIP-chip for four chromosomes.For both Chromatin- immunoprecipation Transcription Factors and Histone modifications. Sequence files and the associated probability files are also provided.
This site offers an enormous collection of photographs of wild species and natural history objects. It covers most groups of organisms with the exception of birds and other vertebrates. The photographs are presented to illustrate biodiversity and as an aid to identification. The criterion for inclusion of a species is that it must have been, or might be expected to be, found in Britain or Ireland. BioImages follows the biological classification. Biota is a hierarchical system with species grouped in genera, genera in families, families in orders and so on up to kingdoms and superkingdoms. The datasets are linked to bioinfo: food webs and species interactions in the Biodiversity of UK and Ireland.