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Found 54 result(s)
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The Autism Chromosome Rearrangement Database is a collection of hand curated breakpoints and other genomic features, related to autism, taken from publicly available literature: databases and unpublished data. The database is continuously updated with information from in-house experimental data as well as data from published research studies.
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As the national oceanographic data centre for Canada, MEDS maintains centralized repositories of some oceanographic data types collected in Canada, and coordinates data exchanges between DFO and recognized intergovernmental organizations, as well as acts as a central point for oceanographic data requests. Real-time, near real-time (for operational oceanography) or historical data are made available as appropriate.
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The Atlantic Canada Conservation Data Centre (ACCDC) maintains comprehensive lists of plant and animal species. The Atlantic CDC has geo-located records of species occurrences and records of extremely rare to uncommon species in the Atlantic region, including New Brunswick, Nova Scotia, Prince Edward Island, Newfoundland, and Labrador. The Atlantic CDC also maintains biological and other types of data in a variety of linked databases.
Data deposit is supported for University of Ottawa faculty, students, and affiliated researchers. The repository is multidisciplinary and hosted on Canadian servers. It includes features such as permanent links (DOIs) which encourage citation of your dataset and help you set terms for access and reuse of your data. uOttawa Dataverse is currently optimal for small to medium datasets.
Reactome is a manually curated, peer-reviewed pathway database, annotated by expert biologists and cross-referenced to bioinformatics databases. Its aim is to share information in the visual representations of biological pathways in a computationally accessible format. Pathway annotations are authored by expert biologists, in collaboration with Reactome editorial staff and cross-referenced to many bioinformatics databases. These include NCBI Gene, Ensembl and UniProt databases, the UCSC and HapMap Genome Browsers, the KEGG Compound and ChEBI small molecule databases, PubMed, and Gene Ontology.
The DRH is a quantitative and qualitative encyclopedia of religious history. It consists of a variety of entry types including religious group and religious place. Scholars contribute entries on their area of expertise by answering questions in standardised polls. Answers are initially coded in the binary format Yes/No or categorically, with comment boxes for qualitative comments, references and links. Experts are able to answer both Yes and No to the same question, enabling nuanced answers for specific circumstances. Media, such as photos, can also be attached to either individual questions or whole entries. The DRH captures scholarly disagreement, through fine-grained records and multiple temporally and spatially overlapping entries. Users can visualise changes in answers to questions over time and the extent of scholarly consensus or disagreement.
<<<!!!<<< This repository is no longer available. >>>!!!>>> NetPath is currently one of the largest open-source repository of human signaling pathways that is all set to become a community standard to meet the challenges in functional genomics and systems biology. Signaling networks are the key to deciphering many of the complex networks that govern the machinery inside the cell. Several signaling molecules play an important role in disease processes that are a direct result of their altered functioning and are now recognized as potential therapeutic targets. Understanding how to restore the proper functioning of these pathways that have become deregulated in disease, is needed for accelerating biomedical research. This resource is aimed at demystifying the biological pathways and highlights the key relationships and connections between them. Apart from this, pathways provide a way of reducing the dimensionality of high throughput data, by grouping thousands of genes, proteins and metabolites at functional level into just several hundreds of pathways for an experiment. Identifying the active pathways that differ between two conditions can have more explanatory power than just a simple list of differentially expressed genes and proteins.
AMCSD is an interface to a crystal structure database that includes every structure published in the American Mineralogist, The Canadian Mineralogist, European Journal of Mineralogy and Physics and Chemistry of Minerals, as well as selected datasets from other journals. The database is maintained under the care of the Mineralogical Society of America and the Mineralogical Association of Canada, and financed by the National Science Foundation. You may search by a mineral of your choice, or choose a mineral from a complete list to help aid your research.
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The Canada Open Data Project provides Government of Canada data to the public as potential driver for economic innovation. Searchable and browsable raw data is available for download, and the public can recommend specific data be made available.
!!! <<< the repository is offline >>> !!! The CBIF provides primary data on biological species of interest to Canadians. CBIF supports a wide range of social and economic decisions including efforts to conserve our biodiversity in healthy ecosystems, use our biological resources in sustainable ways, and monitor and control pests and diseases. Tools provided by the CBIF include the Integrated Taxonomic Information System (ITIS), Species Access Network, Online Mapping, and the SpeciesBank, including Butterflies of Canada. The CBIF is a member of the Global Biodiversity Information Facility (GBIF).
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The Northern Ontario Plant Database (NOPD) is a website that provides free public access to records of herbarium specimens housed in northern Ontario educational and government institutions. A herbarium is an archival collection of plants that have been pressed, dried, mounted, and labelled. It also provides up-to-date and accurate information on the flora of northern Ontario.
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The Cystic Fibrosis Mutation Database (CFTR1) was initiated by the Cystic Fibrosis Genetic Analysis Consortium in 1989 to increase and facilitate communications among CF researchers, and is maintained by the Cystic Fibrosis Centre at the Hospital for Sick Children in Toronto. The specific aim of the database is to provide up to date information about individual mutations in the CFTR gene. In a major upgrade in 2010, all known CFTR mutations and sequence variants have been converted to the standard nomenclature recommended by the Human Genome Variation Society.
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The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. The latest release of DrugBank (version 5.1.1, released 2018-07-03) contains 11,881 drug entries including 2,526 approved small molecule drugs, 1,184 approved biotech (protein/peptide) drugs, 129 nutraceuticals and over 5,751 experimental drugs. Additionally, 5,132 non-redundant protein (i.e. drug target/enzyme/transporter/carrier) sequences are linked to these drug entries. Each DrugCard entry contains more than 200 data fields with half of the information being devoted to drug/chemical data and the other half devoted to drug target or protein data.
Xenbase's mission is to provide the international research community with a comprehensive, integrated and easy to use web based resource that gives access the diverse and rich genomic, expression and functional data available from Xenopus research. Xenbase also provides a critical data sharing infrastructure for many other NIH-funded projects, and is a focal point for the Xenopus community. In addition to our primary goal of supporting Xenopus researchers, Xenbase enhances the availability and visibility of Xenopus data to the broader biomedical research community.
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<<<!!!<<< 2017-06-02: We recently suffered a server failure and are working to bring the full ORegAnno website back online. In the meantime, you may download the complete database here: http://www.oreganno.org/dump/ ; Data are also available through UCSC Genome Browser (e.g., hg38 -> Regulation -> ORegAnno) https://genome.ucsc.edu/cgi-bin/hgTrackUi?hgsid=686342163_2it3aVMQVoXWn0wuCjkNOVX39wxy&c=chr1&g=oreganno >>>!!!>>> The Open REGulatory ANNOtation database (ORegAnno) is an open database for the curation of known regulatory elements from scientific literature. Annotation is collected from users worldwide for various biological assays and is automatically cross-referenced against PubMED, Entrez Gene, EnsEMBL, dbSNP, the eVOC: Cell type ontology, and the Taxonomy database, where appropriate, with information regarding the original experimentation performed (evidence). ORegAnno further provides an open validation process for all regulatory annotation in the public domain. Assigned validators receive notification of new records in the database and are able to cross-reference the citation to ensure record integrity. Validators have the ability to modify any record (deprecating the old record and creating a new one) if an error is found. Further, any contributor to the database can comment on any annotation by marking errors, or adding special reports into function as they see fit. These features of ORegAnno ensure that the collection is of the highest quality and uniquely provides a dynamic view of our changing understanding of gene regulation in the various genomes.
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The CyberCell database (CCDB) is a comprehensive collection of detailed enzymatic, biological, chemical, genetic, and molecular biological data about E. coli (strain K12, MG1655). It is intended to provide sufficient information and querying capacity for biologists and computer scientists to use computers or detailed mathematical models to simulate all or part of a bacterial cell at a nanoscopic (10-9 m), mesoscopic (10-8 m).The CyberCell database CCDB actually consists of 4 browsable databases: 1) the main CyberCell database (CCDB - containing gene and protein information), 2) the 3D structure database (CC3D – containing information for structural proteomics), 3) the RNA database (CCRD – containing tRNA and rRNA information), and 4) the metabolite database (CCMD – containing metabolite information). Each of these databases is accessible through hyperlinked buttons located at the top of the CCDB homepage. All CCDB sub-databases are fully web enabled, permitting a wide variety of interactive browsing, search and display operations. and microscopic (10-6 m) level.
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CCCma has developed a number of climate models. These are used to study climate change and variability, and to understand the various processes which govern the climate system. They are also used to make quantitative projections of future long-term climate change (given various greenhouse gas and aerosol forcing scenarios), and increasingly to make initialized climate predictions on time scales ranging from seasons to decades. A brief description of these models and their corresponding references can be found: https://www.canada.ca/en/environment-climate-change/services/climate-change/science-research-data/modeling-projections-analysis/centre-modelling-analysis/models.html
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Reptiles and amphibians are collectively known as herpetofauna and are a unique part of Ontario’s biodiversity. An earlier atlas, called the Ontario Herpetofaunal Summary Atlas, provided extensive information about where many of the province’s reptiles and amphibians occurred. The Atlas is transitioning into a new era, with Ontario Nature wrapping-up the data collection phase of this project as of December 1, 2019. Now that we have discontinued our app and online form, we encourage you to continue submitting any future observations through the ‘Herps of Ontario’ project (https://www.inaturalist.org/projects/herps-of-ontario) on iNaturalist or directly to the Natural Heritage Information Centre (nhicrequests@ontario.ca) for species at risk. To learn more about the transition, read our blog (https://ontarionature.org/ontario-reptile-and-amphibian-atlas-changes/)
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The CCDS is an interface for distributing climate change information. The goals of CCDS are to: Support climate change impact and adaptation research in Canada and other countries; Support stakeholders requiring scenario information for decision making and policy development. Provide access to Canadian research on the development of scenarios and adaptation research.
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Historical Climate Data (formerly: The National Climate Data and Information Archive - NCDC) is a web-based resource maintained by Environment and Climate Change Canada and the Meteorological Service of Canada. The site houses a number of statistical and data compilation and viewing tools. From the website, users can access historical climate data for Canadian locations and dates, view climate normals and averages, and climate summaries. A list of Canadian air stations and their meteorological reports and activities is also available, along with rainfall statistics for more than 500 locations across Canada. Users can also download the Canadian daily climate data for 2006/07. In addition, technical documentation is offered for data users to interpret the available data. Other documentation includes a catalogue of Canadian weather reporting stations, a glossary, and a calculation of the 1971 to 2000 climate normals for Canada. This resource carries authority and accuracy because it is maintained by a national government department and service. While the majority of the statistics are historical, the data is up-to-date and contains current and fairly recent climate data. This government resource is intended for an audience that has the ability and knowledge to interpret climatological data