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Found 38 result(s)
AceView provides a curated, comprehensive and non-redundant sequence representation of all public mRNA sequences (mRNAs from GenBank or RefSeq, and single pass cDNA sequences from dbEST and Trace). These experimental cDNA sequences are first co-aligned on the genome then clustered into a minimal number of alternative transcript variants and grouped into genes. Using exhaustively and with high quality standards the available cDNA sequences evidences the beauty and complexity of mammals’ transcriptome, and the relative simplicity of the nematode and plant transcriptomes. Genes are classified according to their inferred coding potential; many presumably non-coding genes are discovered. Genes are named by Entrez Gene names when available, else by AceView gene names, stable from release to release. Alternative features (promoters, introns and exons, polyadenylation signals) and coding potential, including motifs, domains, and homologies are annotated in depth; tissues where expression has been observed are listed in order of representation; diseases, phenotypes, pathways, functions, localization or interactions are annotated by mining selected sources, in particular PubMed, GAD and Entrez Gene, and also by performing manual annotation, especially in the worm. In this way, both the anatomy and physiology of the experimentally cDNA supported human, mouse and nematode genes are thoroughly annotated.
ArrayExpress is one of the major international repositories for high-throughput functional genomics data from both microarray and high-throughput sequencing studies, many of which are supported by peer-reviewed publications. Data sets are submitted directly to ArrayExpress and curated by a team of specialist biological curators. In the past (until 2018) datasets from the NCBI Gene Expression Omnibus database were imported on a weekly basis. Data is collected to MIAME and MINSEQE standards.
The Mikulski Archive for Space Telescopes (MAST) is a NASA funded project to support and provide to the astronomical community a variety of astronomical data archives, with the primary focus on scientifically related data sets in the optical, ultraviolet, and near-infrared parts of the spectrum. MAST is located at the Space Telescope Science Institute (STScI).
The goals of the Drosophila Genome Center are to finish the sequence of the euchromatic genome of Drosophila melanogaster to high quality and to generate and maintain biological annotations of this sequence. In addition to genomic sequencing, the BDGP is 1) producing gene disruptions using P element-mediated mutagenesis on a scale unprecedented in metazoans; 2) characterizing the sequence and expression of cDNAs; and 3) developing informatics tools that support the experimental process, identify features of DNA sequence, and allow us to present up-to-date information about the annotated sequence to the research community.
In early 2010 we updated the site to facilitate more rapid transfer of our data to the public database and focus our efforts on the core mission of providing expression pattern images to the research community. The original database https://www.fruitfly.org/index.html reproduced functions available on FlyBase, complicating our updates by the requirement to re-synchronize with FlyBase updates. Our expression reports on the new site still link to FlyBase gene reports, but we no longer reproduce FlyBase functions and therefore can update expression data on an ongoing basis instead of more infrequent major releases. All the functions relating to the expression patterns remain and we soon will add an option to search expression patterns by image similarity, in addition to annotation term searches. In a transitional phase we will leave both the old and the new sites up, but the newer data (post Release 2) will appear only on the new website. We welcome any feedback or requests for additional features. - The goals of the Drosophila Genome Center are to finish the sequence of the euchromatic genome of Drosophila melanogaster to high quality and to generate and maintain biological annotations of this sequence. In addition to genomic sequencing, the BDGP is 1) producing gene disruptions using P element-mediated mutagenesis on a scale unprecedented in metazoans; 2) characterizing the sequence and expression of cDNAs; and 3) developing informatics tools that support the experimental process, identify features of DNA sequence, and allow us to present up-to-date information about the annotated sequence to the research community.
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The China National GeneBank database (CNGBdb) is a unified platform for biological big data sharing and application services. CNGBdb has now integrated a large amount of internal and external biological data from resources such as CNGB, NCBI, and the EBI. There are several sub-databases in CNGBdb, including literature, variation, gene, genome, protein, sequence, organism, project, sample, experiment, run, and assembly. Based on underlying big data and cloud computing technologies, it provides various data services, including archive, analysis, knowledge search, and management authorization of biological data. CNGBdb adopts data structures and standards of international omics, health, and medicine, such as The International Nucleotide Sequence Database Collaboration (INSDC), The Global Alliance for Genomics and Health GA4GH (GA4GH), Global Genome Biodiversity Network (GGBN), American College of Medical Genetics and Genomics (ACMG), and constructs standardized data and structures with wide compatibility. All public data and services provided by CNGBdb are freely available to all users worldwide. CNGB Sequence Archive (CNSA) is the bionomics data repository of CNGBdb. CNGB Sequence Archive (CNSA) is a convenient and efficient archiving system of multi-omics data in life science, which provides archiving services for raw sequencing reads and further analyzed results. CNSA follows the international data standards for omics data, and supports online and batch submission of multiple data types such as Project, Sample, Experiment/Run, Assembly, Variation, Metabolism, Single cell, and Sequence. Moreover, CNSA has achieved the correlation of sample entities, sample information, and analyzed data on some projects. Its data submission service can be used as a supplement to the literature publishing process to support early data sharing.CNGB Sequence Archive (CNSA) is a convenient and efficient archiving system of multi-omics data in the life science of CNGBdb, which provides archiving services for raw sequencing reads and further analyzed results. CNSA follows the international data standards for omics data, and supports online and batch submission of multiple data types such as Project, Sample, Experiment/Run, Assembly, Variation, Metabolism, Single cell, Sequence. Its data submission service can be used as a supplement to the literature publishing process to support early data sharing.
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Chinese Astronomical Data Center (CAsDC) is the scientific data service and infrastructure of National Astronomical Observatories, Chinese Academy of Sciences (NAOC), which is a key service from the China-VO. We are aiming to meet user requirements for astronomical research and education. The CAsDC is based on World Data Center (WDC) for Astronomy, which is hosted at NAOC and has been providing data services to users since its initiation in 1980s. In 2012, the CAsDC became a regular member of the new created World Data System.
The Crustal Dynamics Data Information System (CDDIS) was initially developed to provide a central data bank for NASA's Crustal Dynamics Project (CDP). The Crustal Dynamics Data Information System (CDDIS) supports data archiving and distribution activities for the space geodesy and geodynamics community. The main objectives of the system are to store space geodesy and geodynamics related data products in a central data bank, to maintain information about the archival of these data, and to disseminate these data and information in a timely manner to NASA investigators and cooperating institutions.
The DIP database catalogs experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein interactions. The data stored within the DIP database were curated, both, manually by expert curators and also automatically using computational approaches that utilize the the knowledge about the protein-protein interaction networks extracted from the most reliable, core subset of the DIP data. Please, check the reference page to find articles describing the DIP database in greater detail. The Database of Ligand-Receptor Partners (DLRP) is a subset of DIP (Database of Interacting Proteins). The DLRP is a database of protein ligand and protein receptor pairs that are known to interact with each other. By interact we mean that the ligand and receptor are members of a ligand-receptor complex and, unless otherwise noted, transduce a signal. In some instances the ligand and/or receptor may form a heterocomplex with other ligands/receptors in order to be functional. We have entered the majority of interactions in DLRP as full DIP entries, with links to references and additional information
DDBJ; DNA Data Bank of Japan is the sole nucleotide sequence data bank in Asia, which is officially certified to collect nucleotide sequences from researchers and to issue the internationally recognized accession number to data submitters.Since we exchange the collected data with EMBL-Bank/EBI; European Bioinformatics Institute and GenBank/NCBI; National Center for Biotechnology Information on a daily basis, the three data banks share virtually the same data at any given time. The virtually unified database is called "INSD; International Nucleotide Sequence Database DDBJ collects sequence data mainly from Japanese researchers, but of course accepts data and issue the accession number to researchers in any other countries.
The European Bioinformatics Institute (EBI) has a long-standing mission to collect, organise and make available databases for biomolecular science. It makes available a collection of databases along with tools to search, download and analyse their content. These databases include DNA and protein sequences and structures, genome annotation, gene expression information, molecular interactions and pathways. Connected to these are linking and descriptive data resources such as protein motifs, ontologies and many others. In many of these efforts, the EBI is a European node in global data-sharing agreements involving, for example, the USA and Japan.
Cryo electron microscopy enables the determination of 3D structures of macromolecular complexes and cells from 2 to 100 Å resolution. EMDataResource is the unified global portal for one-stop deposition and retrieval of 3DEM density maps, atomic models and associated metadata, and is a joint effort among investigators of the Stanford/SLAC CryoEM Facility and the Research Collaboratory for Structural Bioinformatics (RCSB) at Rutgers, in collaboration with the EMDB team at the European Bioinformatics Institute. EMDataResource also serves as a resource for news, events, software tools, data standards, and validation methods for the 3DEM community. The major goal of the EMDataResource project in the current funding period is to work with the 3DEM community to (1) establish data-validation methods that can be used in the process of structure determination, (2) define the key indicators of a well-determined structure that should accompany every deposition, and (3) implement appropriate validation procedures for maps and map-derived models into a 3DEM validation pipeline.
The ENCODE Encyclopedia organizes the most salient analysis products into annotations, and provides tools to search and visualize them. The Encyclopedia has two levels of annotations: Integrative-level annotations integrate multiple types of experimental data and ground level annotations. Ground-level annotations are derived directly from the experimental data, typically produced by uniform processing pipelines.
The EPN (or EUREF Permanent Network) is a voluntary organization of several European agencies and universities that pool resources and permanent GNSS station data to generate precise GNSS products. The EPN has been created under the umbrella of the International Association Geodesy and more precisely by its sub-commission EUREF. The European Terrestrial Reference System 89 (ETRS89) is used as the standard precise GPS coordinate system throughout Europe. Supported by EuroGeographics and endorsed by the EU, this reference system forms the backbone for all geographic and geodynamic projects on the European territory both on a national as on an international level.
The European Nucleotide Archive (ENA) captures and presents information relating to experimental workflows that are based around nucleotide sequencing. A typical workflow includes the isolation and preparation of material for sequencing, a run of a sequencing machine in which sequencing data are produced and a subsequent bioinformatic analysis pipeline. ENA records this information in a data model that covers input information (sample, experimental setup, machine configuration), output machine data (sequence traces, reads and quality scores) and interpreted information (assembly, mapping, functional annotation). Data arrive at ENA from a variety of sources. These include submissions of raw data, assembled sequences and annotation from small-scale sequencing efforts, data provision from the major European sequencing centres and routine and comprehensive exchange with our partners in the International Nucleotide Sequence Database Collaboration (INSDC). Provision of nucleotide sequence data to ENA or its INSDC partners has become a central and mandatory step in the dissemination of research findings to the scientific community. ENA works with publishers of scientific literature and funding bodies to ensure compliance with these principles and to provide optimal submission systems and data access tools that work seamlessly with the published literature.
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The repository is no longer available. <<<!!!<<< 2018-08-29: no more access to GAPHYOR >>>!!!>>> Important note: The database was no longer feeded with data or updated in the years 2005-2007. The financial support of the project had been stopped a few yers ahead that time. The maintainance of the IT system couldn't be ensured anymore and system was shutdown in 2015. Please see the other databases in the field.
Satellite-tracked drifting buoys ("drifters") collect measurements of upper ocean currents and sea surface temperatures (SST) around the world as part of the Global Drifter Program. Drifter locations are estimated from 16-20 satellite fixes per day, per drifter. The Drifter Data Assembly Center (DAC) at NOAA's Atlantic Oceanographic and Meteorological Laboratory (AOML) assembles these raw data, applies quality control procedures, and interpolates them via kriging to regular six-hour intervals. The raw observations and processed data are archived at AOML and at the Marine Environmental Data Services (MEDS) in Canada. Two types of data are available: "metadata" contains deployment location and time, time of drogue (sea anchor) loss, date of final transmission, etc. for each drifter. "Interpolated data" contains the quality-controlled, interpolated drifter observations.
GermOnline 4.0 is a cross-species database gateway focusing on high-throughput expression data relevant for germline development, the meiotic cell cycle and mitosis in healthy versus malignant cells. The portal provides access to the Saccharomyces Genomics Viewer (SGV) which facilitates online interpretation of complex data from experiments with high-density oligonucleotide tiling microarrays that cover the entire yeast genome.
The Global Hydrology Resource Center (GHRC) provides both historical and current Earth science data, information, and products from satellite, airborne, and surface-based instruments. GHRC acquires basic data streams and produces derived products from many instruments spread across a variety of instrument platforms.
The HEASARC is a multi-mission astronomy archive for the EUV, X-ray, and Gamma ray wave bands. Because EUV, X and Gamma rays cannot reach the Earth's surface it is necessary to place the telescopes and sensors on spacecraft. The HEASARC now holds the data from 25 observatories covering over 30 years of X-ray, extreme-ultraviolet and gamma-ray astronomy. Data and software from many of the older missions were restored by the HEASARC staff. Examples of these archived missions include ASCA, BeppoSAX, Chandra, Compton GRO, HEAO 1, Einstein Observatory (HEAO 2), EUVE, EXOSAT, HETE-2, INTEGRAL, ROSAT, Rossi XTE, Suzaku, Swift, and XMM-Newton.
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HYdrological cycle in the Mediterranean EXperiemnt. Considering the science and societal issues motivating HyMeX, the programme aims to : improve our understanding of the water cycle, with emphasis on extreme events, by monitoring and modelling the Mediterranean atmosphere-land-ocean coupled system, its variability from the event to the seasonal and interannual scales, and its characteristics over one decade (2010-2020) in the context of global change, assess the social and economic vulnerability to extreme events and adaptation capacity.The multidisciplinary research and the database developed within HyMeX should contribute to: improve observational and modelling systems, especially for coupled systems, better predict extreme events, simulate the long-term water-cycle more accurately, provide guidelines for adaptation measures, especially in the context of global change.
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The CliSAP-Integrated Climate Data Center (ICDC) allows easy access to climate relevant data from satellite remote sensing and in situ and other measurements in Earth System Sciences. These data are important to determine the status and the changes in the climate system. Additionally some relevant re-analysis data are included, which are modeled on the basis of observational data. ICDC cooperates with the "Zentrum für Nachhaltiges Forschungsdatenmanagement "https://www.fdr.uni-hamburg.de/ to publish observational data with a doi.
The IERS provides data on Earth orientation, on the International Celestial Reference System/Frame, on the International Terrestrial Reference System/Frame, and on geophysical fluids. It maintains also Conventions containing models, constants and standards.
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Satellite observations of sea ice concentration in the Arctic and the Antarctic are the backbone of www.meereisportal.de since its launch in April 2013. Since then, daily maps and data sets are published on the information and data portal. Time series and trends are updated daily, representing the status of the sea ice cover on hemispheres. meereisportal.de/seaiceportal.de was laid out as an open portal and shall serve scientific groups performing research on sea ice as a platform for communicating the results of their research.
The NASA Space Science Data Coordinated Archive serves as the permanent archive for NASA space science mission data. "Space science" means astronomy and astrophysics, solar and space plasma physics, and planetary and lunar science. As permanent archive, NSSDCA teams with NASA's discipline-specific space science "active archives" which provide access to data to researchers and, in some cases, to the general public. NSSDCA also serves as NASA's permanent archive for space physics mission data. It provides access to several geophysical models and to data from some non-NASA mission data. In addition to supporting active space physics and astrophysics researchers, NSSDCA also supports the general public both via several public-interest web-based services (e.g., the Photo Gallery) and via the offline mailing of CD-ROMs, photoprints, and other items.