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Found 9 result(s)
The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.
The Database of Protein Disorder (DisProt) is a curated database that provides information about proteins that lack fixed 3D structure in their putatively native states, either in their entirety or in part. DisProt is a community resource annotating protein sequences for intrinsically disorder regions from the literature. It classifies intrinsic disorder based on experimental methods and three ontologies for molecular function, transition and binding partner.
ISG' activities are on educational, research, and data distribution sides: principal purposes of ISG are the collection and distribution of geoid models, the collection and distribution of software for geoid computation, and the organization of technical schools on geoid determinations. ISG collects and disseminates worldwide local and regional geoid models estimated by geodetic Institutions and researchers of many countries. More than 30 countries are represented, listed in alphabetic order or localized on a map
virus mentha archives evidence about viral interactions collected from different sources and presents these data in a complete and comprehensive way. Its data comes from manually curated protein-protein interaction databases that have adhered to the IMEx consortium. virus mentha is a resource that offers a series of tools to analyse selected proteins in the context of a network of interactions. Protein interaction databases archive protein-protein interaction (PPI) information from published articles. However, no database alone has sufficient literature coverage to offer a complete resource to investigate "the interactome". virus mentha's approach generates every week a consistent interactome (graph). Most importantly, the procedure assigns to each interaction a reliability score that takes into account all the supporting evidence. virus mentha offers direct access to viral families such as: Orthomyxoviridae, Orthoretrovirinae and Herpesviridae plus, it offers the unique possibility of searching by host organism. The website and the graphical application are designed to make the data stored in virus mentha accessible and analysable to all users.virus mentha superseeds VirusMINT. The Source databases are: MINT, DIP, IntAct, MatrixDB, BioGRID.
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OGS is recognised as the Italian National Oceanographic Data Centre (OGS-NODC) within the International Oceanographic Data Exchange System of the UNESCO Intergovernmental Oceanographic Commission (IOC) since 27/6/2002. OGS is also listed in EurOcean (Marine Research Infrastructures Database) and in EDMO (European Directory of Marine Organisations). OGS as part of the IOC's network of National Oceanographic Data Centres has designated responsibility for the coordination of data and information management at national level. The oceanographic database covers the fields of marine physics, chemical, biological, underway geophysics and general information on Italian oceanographic cruises and data sets. The main objectives are (revision IODE-XXII, March 2013): -Facilitate and promote the discovery, exchange of, and access to, marine data and information including metadata, products and information in real-time, near real time and delayed mode, through the use of international standards, and in compliance with the IOC Oceanographic Data Exchange Policy for the ocean research and observation community and other stakeholders; - Encourage the long term archival, preservation, documentation, management and services of all marine data, data products, and information; - Develop or use existing best practices for the discovery, management, exchange of, and access to marine data and information, including international standards, quality control and appropriate information technology; - Assist Member States to acquire the necessary capacity to manage marine research and observation data and information and become partners in the IODE network; - Support international scientific and operational marine programmes, including the Framework for Ocean Observing for the benefit of a wide range.
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The Preclinical Image DAtaset Repository (PIDAR) is a public repository of metadata information of preclinical image datasets from any imaging modality associated to peer-review publications. The metadata information are organized in a proper schema to create a standard metadata model for preclinical imaging.