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Found 187 result(s)

Project Achilles

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Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to silence or knock-out individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines provides a complementary approach to those studies that aim to characterize the molecular alterations (e.g. mutations, copy number alterations) of primary tumors, such as The Cancer Genome Atlas (TCGA). The overall goal of the project is to identify cancer genetic dependencies and link them to molecular characteristics in order to prioritize targets for therapeutic development and identify the patient population that might benefit from such targets. Project Achilles data is hosted on the Cancer Dependency Map Portal (DepMap) where it has been harmonized with our genomics and cellular models data. You can access the latest and all past datasets here: https://depmap.org/portal/download/all/

ASAP

A systematic annotation package for community analysis of genomes

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ASAP (a systematic annotation package for community analysis of genomes) is a relational database and web interface developed to store, update and distribute genome sequence data and gene expression data collected by or in collaboration with researchers at the University of Wisconsin - Madison. ASAP was designed to facilitate ongoing community annotation of genomes and to grow with genome projects as they move from the preliminary data stage through post-sequencing functional analysis. The ASAP database includes multiple genome sequences at various stages of analysis, and gene expression data from preliminary experiments.

Fungal Genetics Stock Center

FGSC

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The Fungal Genetics Stock Center has preserved and distributed strains of genetically characterized fungi since 1960. The collection includes over 20,000 accessioned strains of classical and genetically engineered mutants of key model, human, and plant pathogenic fungi. These materials are distributed as living stocks to researchers around the world.

Earth System Grid Federation

ESGF

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The Earth System Grid Federation (ESGF) is an international collaboration with a current focus on serving the World Climate Research Programme's (WCRP) Coupled Model Intercomparison Project (CMIP) and supporting climate and environmental science in general. Data is searchable and available for download at the Federated ESGF-CoG Nodes https://esgf.llnl.gov/nodes.html

Cancer Genomics Hub

CGHub

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>>>>!!!!<<<< The Cancer Genomics Hub mission is now completed. The Cancer Genomics Hub was established in August 2011 to provide a repository to The Cancer Genome Atlas, the childhood cancer initiative Therapeutically Applicable Research to Generate Effective Treatments and the Cancer Genome Characterization Initiative. CGHub rapidly grew to be the largest database of cancer genomes in the world, storing more than 2.5 petabytes of data and serving downloads of nearly 3 petabytes per month. As the central repository for the foundational genome files, CGHub streamlined team science efforts as data became as easy to obtain as downloading from a hard drive. The convenient access to Big Data, and the collaborations that CGHub made possible, are now essential to cancer research. That work continues at the NCI's Genomic Data Commons. All files previously stored at CGHub can be found there. The Website for the Genomic Data Commons is here: https://gdc.nci.nih.gov/ >>>>!!!!<<<< The Cancer Genomics Hub (CGHub) is a secure repository for storing, cataloging, and accessing cancer genome sequences, alignments, and mutation information from the Cancer Genome Atlas (TCGA) consortium and related projects. Access to CGHub Data: All researchers using CGHub must meet the access and use criteria established by the National Institutes of Health (NIH) to ensure the privacy, security, and integrity of participant data. CGHub also hosts some publicly available data, in particular data from the Cancer Cell Line Encyclopedia. All metadata is publicly available and the catalog of metadata and associated BAMs can be explored using the CGHub Data Browser.

FLOSSmole

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FLOSSmole is a collaborative collection of free, libre, and open source software (FLOSS) data. FLOSSmole contains nearly 1 TB of data covering the period 2004 until now, about more than 500,000 different open source projects.

ScienceBase USGS

ScienceBase catalog

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ScienceBase provides access to aggregated information derived from many data and information domains, including feeds from existing data systems, metadata catalogs, and scientists contributing new and original content. ScienceBase architecture is designed to help science teams and data practitioners centralize their data and information resources to create a foundation needed for their work. ScienceBase, both original software and engineered components, is released as an open source project to promote involvement from the larger scientific programming community both inside and outside the USGS.

Junar

Junar Open Data Platform

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Junar provides a cloud-based open data platform that enables innovative organizations worldwide to quickly, easily and affordably make their data accessible to all. In just a few weeks, your initial datasets can be published, providing greater transparency, encouraging collaboration and citizen engagement, and freeing up precious staff resources.

Avian Knowledge Network

AKN

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The Avian Knowledge Network (AKN) is an international network of governmental and non-governmental institutions and individuals linking avian conservation, monitoring and science through efficient data management and coordinated development of useful solutions using best-science practices based on the data.

OpenWorm

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OpenWorm aims to build the first comprehensive computational model of the Caenorhabditis elegans (C. elegans), a microscopic roundworm. With only a thousand cells, it solves basic problems such as feeding, mate-finding and predator avoidance. Despite being extremely well studied in biology, this organism still eludes a deep, principled understanding of its biology. We are using a bottom-up approach, aimed at observing the worm behaviour emerge from a simulation of data derived from scientific experiments carried out over the past decade. To do so we are incorporating the data available in the scientific community into software models. We are engineering Geppetto and Sibernetic, open-source simulation platforms, to be able to run these different models in concert. We are also forging new collaborations with universities and research institutes to collect data that fill in the gaps All the code we produce in the OpenWorm project is Open Source and available on GitHub.

Gulf Coast Repository

GCR

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The International Ocean Discovery Program’s (IODP) Gulf Coast Repository (GCR) is located in the Research Park on the Texas A&M University campus in College Station, Texas. This repository stores DSDP, ODP, and IODP cores from the Pacific Ocean, the Caribbean Sea and Gulf of Mexico, and the Southern Ocean. A satellite repository at Rutgers University houses New Jersey/Delaware land cores 150X and 174AX.

Reality Commons

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Cell phones have become an important platform for the understanding of social dynamics and influence, because of their pervasiveness, sensing capabilities, and computational power. Many applications have emerged in recent years in mobile health, mobile banking, location based services, media democracy, and social movements. With these new capabilities, we can potentially be able to identify exact points and times of infection for diseases, determine who most influences us to gain weight or become healthier, know exactly how information flows among employees and productivity emerges in our work spaces, and understand how rumors spread. In an attempt to address these challenges, we release several mobile data sets here in "Reality Commons" that contain the dynamics of several communities of about 100 people each. We invite researchers to propose and submit their own applications of the data to demonstrate the scientific and business values of these data sets, suggest how to meaningfully extend these experiments to larger populations, and develop the math that fits agent-based models or systems dynamics models to larger populations. These data sets were collected with tools developed in the MIT Human Dynamics Lab and are now available as open source projects or at cost.

TheDataWeb

DataFerrett

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<<<!!!<<< This repository is no longer available. >>>!!!>>> Be advised that DataFerrett was decommissioned June 30, 2020; see https://www.census.gov/data/data-tools/dataferrett.html

Bigelow National Center for Algae and Microbiota

formerly: CCMP

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The NCMA maintains the largest and most diverse collection of publically available marine algal strains in the world. The algal strains in the collection have been obtained from all over the world, from polar to tropical waters, marine, freshwater, brackish, and hyper-saline environments. New strains (50 - 100 per year) are added largely through the accession of strains deposited by scientists in the community. A stringent accession policy is required to help populate the collection with a diverse range of strains.

St. Edward's University institutional repository

St. Edward’s University Figshare

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Additionally to the institutional repository, current St. Edward's faculty have the option of uploading their work directly to their own SEU accounts on stedwards.figshare.com. Projects created on Figshare will automatically be published on this website as well. For more information, please see documentation

GeneWeaver.org

The Ontological Discovery Environment

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GeneWeaver combines cross-species data and gene entity integration, scalable hierarchical analysis of user data with a community-built and curated data archive of gene sets and gene networks, and tools for data driven comparison of user-defined biological, behavioral and disease concepts. Gene Weaver allows users to integrate gene sets across species, tissue and experimental platform. It differs from conventional gene set over-representation analysis tools in that it allows users to evaluate intersections among all combinations of a collection of gene sets, including, but not limited to annotations to controlled vocabularies. There are numerous applications of this approach. Sets can be stored, shared and compared privately, among user defined groups of investigators, and across all users.

Triticeae Toolbox

T3

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A database for plant breeders and researchers to combine, visualize, and interrogate the wealth of phenotype and genotype data generated by the Triticeae Coordinated Agricultural Project (TCAP).

Research Computing and Data Services

formerly name: Northwest Knowledge Network

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NKN is now Research Computing and Data Services (RCDS)! We provide data management support for UI researchers and their regional, national, and international collaborators. This support keeps researchers at the cutting-edge of science and increases our institution's competitiveness for external research grants. Quality data and metadata developed in research projects and curated by RCDS (formerly NKN) is a valuable, long-term asset upon which to develop and build new research and science.

Qualitative Data Repository

QDR

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The Qualitative Data Repository (QDR) is a dedicated archive for storing and sharing digital data (and accompanying documentation) generated or collected through qualitative and multi-method research in the social sciences. QDR provides data management consulting services and actively curates all data projects, maintaining the value and usefulness of the data over time, and ensuring their availability and findability for re-use.

FILER: Functional genomics repository

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Harmonized, indexed, searchable large-scale human FG data collection with extensive metadata. Provides scalable, unified way to easily access massive functional genomics (FG) and annotation data collections curated from large-scale genomic studies. Direct integration (API) with custom / high-throughput genetic and genomic analysis workflows.

Earth Engine Data Catalog

Google Earth Engine

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A planetary-scale platform for Earth science data & analysis. Google Earth Engine combines a multi-petabyte catalog of satellite imagery and geospatial datasets with planetary-scale analysis capabilities. Scientists, researchers, and developers use Earth Engine to detect changes, map trends, and quantify differences on the Earth's surface.

Canadian Open Neuroscience Platform Portal

CONP

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The CONP portal is a web interface for the Canadian Open Neuroscience Platform (CONP) to facilitate open science in the neuroscience community. CONP simplifies global researcher access and sharing of datasets and tools. The portal internalizes the cycle of a typical research project: starting with data acquisition, followed by processing using already existing/published tools, and ultimately publication of the obtained results including a link to the original dataset. From more information on CONP, please visit https://conp.ca

OpenTopography

A Portal to High-Resolution Topography Data and Tools

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OpenTopography facilitates community access to high-resolution, Earth science-oriented, topography data, and related tools and resources. The OpenTopography Facility is based at the San Diego Supercomputer Center at the University of California, San Diego and is operated in collaboration with colleagues in the School of Earth and Space Exploration at Arizona State University and Earthscope Consortium. Core operational support for OpenTopography comes from the National Science Foundation Earth Sciences.

Atmosphere to Electrons, Data Archive and Portal

A2e, DAP

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Atmosphere to Electrons (A2e) is a new, multi-year, multi-stakeholder U.S. Department of Energy (DOE) research and development initiative tasked with improving wind plant performance and mitigating risk and uncertainty to achieve substantial reduction in the cost of wind energy production. The A2e strategic vision will enable a new generation of wind plant technology, in which smart wind plants are designed to achieve optimized performance stemming from more complete knowledge of the inflow wind resource and complex flow through the wind plant.

Internet Archive

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The Internet Archive includes texts, audio, moving images, software, and archived web pages.