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Found 402 result(s)
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The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. The latest release of DrugBank (version 5.1.1, released 2018-07-03) contains 11,881 drug entries including 2,526 approved small molecule drugs, 1,184 approved biotech (protein/peptide) drugs, 129 nutraceuticals and over 5,751 experimental drugs. Additionally, 5,132 non-redundant protein (i.e. drug target/enzyme/transporter/carrier) sequences are linked to these drug entries. Each DrugCard entry contains more than 200 data fields with half of the information being devoted to drug/chemical data and the other half devoted to drug target or protein data.
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BLLAST is a research programme aimed at exploring the late afternoon transition of the atmospheric boundary layer. The late afternoon period of the diurnal cycle of the boundary layer is poorly understood. This is yet an important transition period that impacts the transport and dillution of water vapour and trace species. The main questions adressed by the project are: - How the turbulence activity fades when heating by the surface decreases? - What is the impact on the transport of chemical species? - How relevant processes can be represented in numerical models? To answer all these questions, a field campaign was carried out during the summer of 2011 (from June 14 to July 8). Many observation systems were then deployed and operated by research teams coming from France and abroad. They were spanning a large spectrum of space and time scales in order to achieve a comprehensive description of the boundary layer processes. The observation strategy consisted in intensifying the operations in the late afternoon with tethered balloons, resarch aircrafts and UAVs.
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University of Warsaw Research Data Repository aims to collect, archive, preserve and make available all types of research data. Storing and making data available is possible for users affiliated with the University of Warsaw, Poland, or those involved in projects carried out in partnership with the University of Warsaw. Browsing and downloading publicly available research data is open to all interested.
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"IndExs" is a database comprising information on exsiccatae (=exsiccatal series) with titles, abbreviations, bibliography and provides a unique and persistent Exsiccata ID for each series. Exsiccatae are defined as "published, uniform, numbered sets of preserved specimens distributed with printed labels" (Pfister 1985). Please note that there are two similar latin terms: "exsiccata, ae" is feminine and used for a set of dried specimens as defined above, whereas the term "exsiccatum, i" is neutral and used for dried specimens in general. If available, images of one or more examplary labels are added to give layout information.
mentha archives evidence collected from different sources and presents these data in a complete and comprehensive way. Its data comes from manually curated protein-protein interaction databases that have adhered to the IMEx consortium. The aggregated data forms an interactome which includes many organisms. mentha is a resource that offers a series of tools to analyse selected proteins in the context of a network of interactions. Protein interaction databases archive protein-protein interaction (PPI) information from published articles. However, no database alone has sufficient literature coverage to offer a complete resource to investigate "the interactome". mentha's approach generates every week a consistent interactome (graph). Most importantly, the procedure assigns to each interaction a reliability score that takes into account all the supporting evidence. mentha offers eight interactomes (Homo sapiens, Arabidopsis thaliana, Caenorhabditis elegans, Drosophila melanogaster, Escherichia coli K12, Mus musculus, Rattus norvegicus, Saccharomyces cerevisiae) plus a global network that comprises every organism, including those not mentioned. The website and the graphical application are designed to make the data stored in mentha accessible and analysable to all users. Source databases are: MINT, IntAct, DIP, MatrixDB and BioGRID.
The Saccharomyces Genome Database (SGD) provides comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae along with search and analysis tools to explore these data, enabling the discovery of functional relationships between sequence and gene products in fungi and higher organisms.
Sandrart.net: A net-based research platform on the history of art and culture in the 17th century. The project’s main goal was an annotated, enriched and web-based edition of Joachim von Sandrart’s Teutscher Academie der Edlen Bau, Bild- und Mahlerey-Künste (1675–80), one of the most important source texts of the early modern period. Having lived and worked in a number of places throughout Europe, Sandrart’s biographical background makes his writings (with first-hand narrations on art, artists and art collections) a work of European dimension.
PharmGKB is a comprehensive resource that curates knowledge about the impact of genetic variation on drug response for clinicians and researchers. PharmGKB brings together the relevant data in a single place and adds value by combining disparate data on the same relationship, making it easier to search and easier to view the key aspects and by interpreting the data.PharmGKB provide clinical interpretations of this data, curated pathways and VIP summaries which are not found elsewhere.
VectorBase provides data on arthropod vectors of human pathogens. Sequence data, gene expression data, images, population data, and insecticide resistance data for arthropod vectors are available for download. VectorBase also offers genome browser, gene expression and microarray repository, and BLAST searches for all VectorBase genomes. VectorBase Genomes include Aedes aegypti, Anopheles gambiae, Culex quinquefasciatus, Ixodes scapularis, Pediculus humanus, Rhodnius prolixus. VectorBase is one the Bioinformatics Resource Centers (BRC) projects which is funded by National Institute of Allergy and Infectious Diseases (NAID).
enviPath is a database and prediction system for the microbial biotransformation of organic environmental contaminants. The database provides the possibility to store and view experimentally observed biotransformation pathways. The pathway prediction system provides different relative reasoning models to predict likely biotransformation pathways and products.
DEIMS-SDR (Dynamic Ecological Information Management System - Site and dataset registry) is an information management system that allows you to discover long-term ecosystem research sites around the globe, along with the data gathered at those sites and the people and networks associated with them. DEIMS-SDR describes a wide range of sites, providing a wealth of information, including each site’s location, ecosystems, facilities, parameters measured and research themes. It is also possible to access a growing number of datasets and data products associated with the sites. All sites and dataset records can be referenced using unique identifiers that are generated by DEIMS-SDR. It is possible to search for sites via keyword, predefined filters or a map search. By including accurate, up to date information in DEIMS, site managers benefit from greater visibility for their LTER site, LTSER platform and datasets, which can help attract funding to support site investments. The aim of DEIMS-SDR is to be the globally most comprehensive catalogue of environmental research and monitoring facilities, featuring foremost but not exclusively information about all LTER sites on the globe and providing that information to science, politics and the public in general.
The Polinsky Language Sciences Lab at Harvard University is a linguistics lab that examines questions of language structure and its effect on the ways in which people use and process language in real time. We engage in linguistic and interdisciplinary research projects ourselves; offer linguistic research capabilities for undergraduate and graduate students, faculty, and visitors; and build relationships with the linguistic communities in which we do our research. We are interested in a broad range of issues pertaining to syntax, interfaces, and cross-linguistic variation. We place a particular emphasis on novel experimental evidence that facilitates the construction of linguistic theory. We have a strong cross-linguistic focus, drawing upon English, Russian, Chinese, Korean, Mayan languages, Basque, Austronesian languages, languages of the Caucasus, and others. We believe that challenging existing theories with data from as broad a range of languages as possible is a crucial component of the successful development of linguistic theory. We investigate both fluent speakers and heritage speakers—those who grew up hearing or speaking a particular language but who are now more fluent in a different, societally dominant language. Heritage languages, a novel field of linguistic inquiry, are important because they provide new insights into processes of linguistic development and attrition in general, thus increasing our understanding of the human capacity to maintain and acquire language. Understanding language use and processing in real time and how children acquire language helps us improve language study and pedagogy, which in turn improves communication across the globe. Although our lab does not specialize in language acquisition, we have conducted some studies of acquisition of lesser-studied languages and heritage languages, with the purpose of comparing heritage speakers to adults.
LibraData is a place for UVA researchers to share data publicly. It is UVA's local instance of Dataverse. LibraData is part of the Libra Scholarly Repository suite of services which includes works of UVA scholarship such as articles, books, theses, and data.
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The National Archives and Records Administration (NARA) is the nation's record keeper. Of all documents and materials created in the course of business conducted by the United States Federal government, only 1%-3% are so important for legal or historical reasons that they are kept by us forever. Those valuable records are preserved and are available to you, whether you want to see if they contain clues about your family’s history, need to prove a veteran’s military service, or are researching an historical topic that interests you.
The MG-RAST server is an open source system for annotation and comparative analysis of metagenomes. Users can upload raw sequence data in fasta format; the sequences will be normalized and processed and summaries automatically generated. The server provides several methods to access the different data types, including phylogenetic and metabolic reconstructions, and the ability to compare the metabolism and annotations of one or more metagenomes and genomes. In addition, the server offers a comprehensive search capability. Access to the data is password protected, and all data generated by the automated pipeline is available for download in a variety of common formats. MG-RAST has become an unofficial repository for metagenomic data, providing a means to make your data public so that it is available for download and viewing of the analysis without registration, as well as a static link that you can use in publications. It also requires that you include experimental metadata about your sample when it is made public to increase the usefulness to the community.
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The City of Victoria’s Open Data Portal allows you to explore and download open data, discover and analyze datasets using maps, and develop new web and mobile applications.
Gemma is a database for the meta-analysis, re-use and sharing of genomics data, currently primarily targeted at the analysis of gene expression profiles. Gemma contains data from thousands of public studies, referencing thousands of published papers. Users can search, access and visualize co-expression and differential expression results.
M-CSA is a database of enzyme reaction mechanisms. It provides annotation on the protein, catalytic residues, cofactors, and the reaction mechanisms of hundreds of enzymes. There are two kinds of entries in M-CSA. 'Detailed mechanism' entries are more complete and show the individual chemical steps of the mechanism as schemes with electron flow arrows. 'Catalytic Site' entries annotate the catalytic residues necessary for the reaction, but do not show the mechanism. The M-CSA (Mechanism and Catalytic Site Atlas) represents a unified resource that combines the data in both MACiE and the CSA
The Protein Data Bank (PDB) archive is the single worldwide repository of information about the 3D structures of large biological molecules, including proteins and nucleic acids. These are the molecules of life that are found in all organisms including bacteria, yeast, plants, flies, other animals, and humans. Understanding the shape of a molecule helps to understand how it works. This knowledge can be used to help deduce a structure's role in human health and disease, and in drug development. The structures in the archive range from tiny proteins and bits of DNA to complex molecular machines like the ribosome.
LAADS DAAC is the web interface to the Level 1 and Atmosphere Archive and Distribution System (LAADS). The mission of LAADS is to provide quick and easy access to MODIS Level 1, Atmosphere and Land data products, VIIRS Level 1 and Land data products MAS and MERIS data products. MODIS (or Moderate Resolution Imaging Spectroradiometer) is a key instrument aboard the Terra (EOS AM) and Aqua (EOS PM) satellites.