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Found 149 result(s)
Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to silence or knock-out individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines provides a complementary approach to those studies that aim to characterize the molecular alterations (e.g. mutations, copy number alterations) of primary tumors, such as The Cancer Genome Atlas (TCGA). The overall goal of the project is to identify cancer genetic dependencies and link them to molecular characteristics in order to prioritize targets for therapeutic development and identify the patient population that might benefit from such targets. Project Achilles data is hosted on the Cancer Dependency Map Portal (DepMap) where it has been harmonized with our genomics and cellular models data. You can access the latest and all past datasets here: https://depmap.org/portal/download/all/
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The Northern Ontario Plant Database (NOPD) is a website that provides free public access to records of herbarium specimens housed in northern Ontario educational and government institutions. A herbarium is an archival collection of plants that have been pressed, dried, mounted, and labelled. It also provides up-to-date and accurate information on the flora of northern Ontario.
The Archaeological Map of the Czech Republic (AMCR) is a repository designed for information on archaeological investigations, sites and finds, operated by the Archaeological Institutes of the CAS in Prague and Brno. The archives of these institutions contain documentation of archaeological fieldwork on the territory of the Czech Republic from 1919 to the present day, and they continue to enrich their collections. The AMCR database and related documents form the largest collection of archaeological data concerning the Czech Republic and are therefore an important part of our cultural heritage. The AMCR digital archive contains various types of records - individual archaeological documents (texts, field photographs, aerial photographs, maps and plans, digital data), projects, fieldwork events, archaeological sites, records of individual finds and a library of 3D models. Data and descriptive information are continuously taken from the AMCR and presented in the the AMCR Digital Archive interface.
The Bremen Core Repository - BCR, for International Ocean Discovery Program (IODP), Integrated Ocean Discovery Program (IODP), Ocean Drilling Program (ODP), and Deep Sea Drilling Project (DSDP) cores from the Atlantic Ocean, Mediterranean and Black Seas and Arctic Ocean is operated at University of Bremen within the framework of the German participation in IODP. It is one of three IODP repositories (beside Gulf Coast Repository (GCR) in College Station, TX, and Kochi Core Center (KCC), Japan). One of the scientific goals of IODP is to research the deep biosphere and the subseafloor ocean. IODP has deep-frozen microbiological samples from the subseafloor available for interested researchers and will continue to collect and preserve geomicrobiology samples for future research.
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NONCODE is an integrated knowledge database dedicated to non-coding RNAs (excluding tRNAs and rRNAs). Now, there are 16 species in NONCODE(human, mouse, cow, rat, chicken, fruitfly, zebrafish, celegans, yeast, Arabidopsis, chimpanzee, gorilla, orangutan, rhesus macaque, opossum and platypus).The source of NONCODE includes literature and other public databases. We searched PubMed using key words ‘ncrna’, ‘noncoding’, ‘non-coding’,‘no code’, ‘non-code’, ‘lncrna’ or ‘lincrna. We retrieved the new identified lncRNAs and their annotation from the Supplementary Material or web site of these articles. Together with the newest data from Ensembl , RefSeq, lncRNAdb and GENCODE were processed through a standard pipeline for each species.
IMGT® is a pioneering international information system in immunogenetics and immunoinformatics. It provides databases and tools based on the IMGT-ONTOLOGY to the scientific community for in-depth exploration of the adaptive immune response. IMGT® is dedicated to advancing scientific knowledge through its three main axes of research and development.
DATA.NASA.GOV is NASA's clearinghouse site for open-data provided to the public. Tens of thousands of datasets are available for you. This site is a continually growing catalog of publicly available NASA Datasets, APIs, Visualizations, and more.
<<<!!!<<< OFFLINE >>>!!!>>> A recent computer security audit has revealed security flaws in the legacy HapMap site that require NCBI to take it down immediately. We regret the inconvenience, but we are required to do this. That said, NCBI was planning to decommission this site in the near future anyway (although not quite so suddenly), as the 1,000 genomes (1KG) project has established itself as a research standard for population genetics and genomics. NCBI has observed a decline in usage of the HapMap dataset and website with its available resources over the past five years and it has come to the end of its useful life. The International HapMap Project is a multi-country effort to identify and catalog genetic similarities and differences in human beings. Using the information in the HapMap, researchers will be able to find genes that affect health, disease, and individual responses to medications and environmental factors. The Project is a collaboration among scientists and funding agencies from Japan, the United Kingdom, Canada, China, Nigeria, and the United States. All of the information generated by the Project will be released into the public domain. The goal of the International HapMap Project is to compare the genetic sequences of different individuals to identify chromosomal regions where genetic variants are shared. By making this information freely available, the Project will help biomedical researchers find genes involved in disease and responses to therapeutic drugs. In the initial phase of the Project, genetic data are being gathered from four populations with African, Asian, and European ancestry. Ongoing interactions with members of these populations are addressing potential ethical issues and providing valuable experience in conducting research with identified populations. Public and private organizations in six countries are participating in the International HapMap Project. Data generated by the Project can be downloaded with minimal constraints. The Project officially started with a meeting in October 2002 (https://www.genome.gov/10005336/) and is expected to take about three years.
<<<!!!<<< This repository is no longer available. >>>!!!>>> BioVeL is a virtual e-laboratory that supports research on biodiversity issues using large amounts of data from cross-disciplinary sources. BioVeL supports the development and use of workflows to process data. It offers the possibility to either use already made workflows or create own. BioVeL workflows are stored in MyExperiment - Biovel Group http://www.myexperiment.org/groups/643/content. They are underpinned by a range of analytical and data processing functions (generally provided as Web Services or R scripts) to support common biodiversity analysis tasks. You can find the Web Services catalogued in the BiodiversityCatalogue.
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Various information, such as xylarium data with wood specimens collected since 1944, atmospheric observation data using the MU radar and other instruments, space-plasma data observed with GEOTAIL satellite, are now combined as Database of Humanosphere and served for public use. Proposals for scientific and technological use are always welcome.
TAED is a database of phylogenetically indexed gene families. It contains multiple sequence alignments from MAFFT1, maximum likelihood phylogenetic trees from PhyML2, bootstrap values for each node, dN/dS ratios for each lineage from the free ratios model in PAML3, and labels for each node of speciation or duplication from gene tree/species tree reconciliation using SoftParsMap4. The phylogenetic indexing enables simultaneous viewing of lineages with high dN/dS that occurred along the same species tree branches. Resources from the Protein Data Bank (PDB) and the Kyoto Encyclopedia of Genes and Genomes (KEGG)5, have been incorporated into the TAED analysis to detect substitutions along each branch within the phylogenetic tree and to assess selection within pathways.
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CCCma has developed a number of climate models. These are used to study climate change and variability, and to understand the various processes which govern the climate system. They are also used to make quantitative projections of future long-term climate change (given various greenhouse gas and aerosol forcing scenarios), and increasingly to make initialized climate predictions on time scales ranging from seasons to decades. A brief description of these models and their corresponding references can be found: https://www.canada.ca/en/environment-climate-change/services/climate-change/science-research-data/modeling-projections-analysis/centre-modelling-analysis/models.html
NOAA's National Centers for Environmental Information (NCEI) are responsible for hosting and providing public access to one of the most significant archives for environmental data on Earth with over 20 petabytes of comprehensive atmospheric, coastal, oceanic, and geophysical data. NCEI headquarters are located in Asheville, North Carolina. Most employees work in the four main locations, but apart from those locations, NCEI has employees strategically located throughout the United States. The main locations are Cooperative Institute for Climate and Satellites–North Carolina (CICS-NC) at Asheville, North Carolina, Cooperative Institute for Research in Environmental Sciences (CIRES) at Boulder Colorado, Cooperative Institute for Climate and Satellites–Maryland (CICS-MD) at Silver Spring Maryland and Stennis Space Center, Mississippi.
The Common Cold Project began in 2011 with the aim of creating, documenting, and archiving a database that combines final research data from 5 prospective viral-challenge studies that were conducted over the preceding 25 years: the British Cold Study (BCS); the three Pittsburgh Cold Studies (PCS1, PCS2, and PCS3); and the Pittsburgh Mind-Body Center Cold Study (PMBC). These unique studies assessed predictor (and hypothesized mediating) variables in healthy adults aged 18 to 55 years, experimentally exposed them to a virus that causes the common cold, and then monitored them for development of infection and signs and symptoms of illness.
Born in Bradford is one of the biggest and most important medical research studies undertaken in the UK. The project started in 2007 and is looking to answer questions about our health by tracking the lives of 13,500 babies and their families and will provide information for studies across the UK and around the world. The aim of Born in Bradford is to find out more about the causes of childhood illness by studying children from all cultures and backgrounds as their lives unfold.
High spatial resolution, contemporary data on human population distributions are a prerequisite for the accurate measurement of the impacts of population growth, for monitoring changes and for planning interventions. The WorldPop project aims to meet these needs through the provision of detailed and open access population distribution datasets built using transparent approaches. The WorldPop project was initiated in October 2013 to combine the AfriPop, AsiaPop and AmeriPop population mapping projects. It aims to provide an open access archive of spatial demographic datasets for Central and South America, Africa and Asia to support development, disaster response and health applications. The methods used are designed with full open access and operational application in mind, using transparent, fully documented and peer-reviewed methods to produce easily updatable maps with accompanying metadata and measures of uncertainty.
Vast networks of meteorological sensors ring the globe measuring atmospheric state variables, like temperature, humidity, wind speed, rainfall, and atmospheric carbon dioxide, on a continuous basis. These measurements serve earth system science by providing inputs into models that predict weather, climate and the cycling of carbon and water. And, they provide information that allows researchers to detect the trends in climate, greenhouse gases, and air pollution. The eddy covariance method is currently the standard method used by biometeorologists to measure fluxes of trace gases between ecosystems and atmosphere.
Climate Data Online (CDO) provides free access to NCDC's archive of global historical weather and climate data in addition to station history information. These data include quality controlled daily, monthly, seasonal, and yearly measurements of temperature, precipitation, wind, and degree days as well as radar data and 30-year Climate Normals
The Malaria Atlas Project (MAP) brings together researchers based around the world with expertise in a wide range of disciplines from public health to mathematics, geography and epidemiology. We work together to generate new and innovative methods of mapping malaria risk. Ultimately our goal is to produce a comprehensive range of maps and estimates that will support effective planning of malaria control at national and international scales.
ITER is an Internet database of human health risk values and cancer classifications for over 680 chemicals of environmental concern from multiple organizations wordwide. ITER is the only database that presents risk data in a tabular format for easy comparison, along with a synopsis explaining differences in data and a link to each organization for more information.
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Tethys is an Open Access Research Data Repository of the GeoSphere Austria, which publishes and distributes georeferenced geoscientific research data generated at and in cooperation with the GeoSphere Austria. The research data publications and the associated metadata are predominantly provided in German or in English. The abstracts are provided in both languages. Tethys aims to provide published data sets as open data and in accordance with the FAIR Data Principles, findable, accessible, interoperable and reusable.
TCIA is a service which de-identifies and hosts a large archive of medical images of cancer accessible for public download. The data are organized as “collections”; typically patients’ imaging related by a common disease (e.g. lung cancer), image modality or type (MRI, CT, digital histopathology, etc) or research focus. Supporting data related to the images such as patient outcomes, treatment details, genomics and expert analyses are also provided when available.
The Migrant Integration Policy Index (MIPEX) is a unique tool that measures policies to integrate migrants in all EU Member States, Australia, Canada, Iceland, Japan, South Korea, New Zealand, Norway, Switzerland, Turkey and the USA. 167 policy indicators have been developed to create a rich, multi-dimensional picture of migrants’ opportunities to participate in society. The index is a useful tool to evaluate and compare what governments are doing to promote the integration of migrants in all the countries analysed.