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Found 214 result(s)

Liverpool COVID-19 Drug Interactions

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The COVID-19 pandemic has affected every country in the world. It is well documented that those most susceptible to the worst outcomes of COVID-19 are the immunocompromised and those with underlying comorbidities. Therefore, patients requiring treatment for COVID-19 will also be on additional medication, posing a risk for drug-drug interactions (DDIs). In order to address this, the Liverpool Drug Interactions website team developed this freely available drug interactions resource to provide information on the likelihood of interactions between the experimental agents used for the treatment of COVID-19 and commonly prescribed co-medications.

GALENOS Data Repository

Global Alliance for Living Evidence on aNxiety, depressiOn and pSychosis Data Repository

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Welcome to the GALENOS Data Repository. The GALENOS Data Repository provides access to all the research data produced by the Global Alliance for Living Evidence on aNxiety, depressiOn and pSychosis (GALENOS). If you're interested in learning more about GALENOS, please visit the website at https://galenos.org.uk.

CATH

CATH-Gene3D

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The CATH database is a hierarchical domain classification of protein structures in the Protein Data Bank. Protein structures are classified using a combination of automated and manual procedures. There are four major levels in the CATH hierarchy; Class, Architecture, Topology and Homologous superfamily.

Comprehensive Antibiotic Resistance Database

CARD

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A bioinformatic database of antimicrobial resistance genes, their products and associated phenotypes.

Pfam Protein Families

Pfam

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<<<!!!<<< Pfam data and new releases are available through InterPro https://www.re3data.org/repository/r3d100010798 The Pfam website now serves as a static page with no data updates. All links below redirect to the closest alternative page in the InterPro website. >>>!!!>>>

DEPOD

DEPhOsphorylation Database

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DEPOD - the human DEPhOsphorylation Database (version 1.1) is a manually curated database collecting human active phosphatases, their experimentally verified protein and non-protein substrates and dephosphorylation site information, and pathways in which they are involved. It also provides links to popular kinase databases and protein-protein interaction databases for these phosphatases and substrates. DEPOD aims to be a valuable resource for studying human phosphatases and their substrate specificities and molecular mechanisms; phosphatase-targeted drug discovery and development; connecting phosphatases with kinases through their common substrates; completing the human phosphorylation/dephosphorylation network.

TwinsUK

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The TwinsUK resource is the biggest UK adult twin registry of 14.000 twins used to study the genetic and environmental aetiology of age related complex traits and diseases.

Avon Longitudinal Study of Parents and Children

ALSPAC

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ALSPAC is a longitudinal birth cohort study which enrolled pregnant women who were resident in one of three Bristol-based health districts in the former County of Avon with an expected delivery date between 1st April 1991 and 31st December 1992. Around 14,000 pregnant women were initially recruited. Detailed information has been collected on these women, their partners and subsequent children using self-completion questionnaires, data extraction from medical notes, linkage to routine information systems and from hands-on research clinics. Additional cohorts of participants have since been enrolled in their own right including fathers, siblings, children of the children and grandparents of the children. Ethical approval for the study was obtained from the ALSPAC Ethics and Law Committee (IRB00003312) and Local Research Ethics.

MRC National Survey of Health and Development

NSHD

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The MRC National Survey of Health and Development 1946 (NSHD) was the first ever British birth cohort study. It has collected information from birth to the current day on the health and life circumstances of five and a half thousand men and women born during a week in March 1946 throughout England, Wales, and Scotland. The study explores differences in child development by factors like social class, biological factors, health and education. Due to the length of the study it has developed into a study of ageing.

Bicocca Open Archive Research Data

BOARD

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BOARD (Bicocca Open Archive Research Data) is the institutional data repository of the University of Milano-Bicocca. BOARD is an open, free-to-use research data repository, which enables members of University of Milano-Bicocca to make their research data publicly available. By depositing their research data in BOARD researchers can: - Make their research data citable - Share their data privately or publicly - Ensure long-term storage for their data - Keep access to all versions - Link their article to their data

FAIRsharing

formerly: biosharing

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FAIRsharing is a web-based, searchable portal of three interlinked registries, containing both in-house and crowdsourced manually curated descriptions of standards, databases and data policies, combined with an integrated view across all three types of resource. By registering your resource on FAIRsharing, you not only gain credit for your work, but you increase its visibility outside of your direct domain, so reducing the potential for unnecessary reinvention and proliferation of standards and databases.

AlgaeBase

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AlgaeBase is a database of information on algae that includes terrestrial, marine and freshwater organisms. At present, the data for the marine algae, particularly seaweeds, are the most complete.

The Universal Protein Resource

UniProt

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The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).

UniRef

UniProt Reference Clusters

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The UniProt Reference Clusters (UniRef) provide clustered sets of sequences from the UniProt Knowledgebase (including isoforms) and selected UniParc records in order to obtain complete coverage of the sequence space at several resolutions while hiding redundant sequences (but not their descriptions) from view.

UniParc

UniProt Archive

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The UniProt Archive (UniParc) is a comprehensive and non-redundant database that contains most of the publicly available protein sequences in the world.

ISRCTN Registry

International Standard Randomised Controlled Trial Number Registry

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The ISRCTN registry is a primary clinical trial registry recognised by WHO and ICMJE that accepts all clinical research studies (whether proposed, ongoing or completed), providing content validation and curation and the unique identification number necessary for publication. All study records in the database are freely accessible and searchable. ISRCTN supports transparency in clinical research, helps reduce selective reporting of results and ensures an unbiased and complete evidence base. ISRCTN accepts all studies involving human subjects or populations with outcome measures assessing effects on human health and well-being, including studies in healthcare, social care, education, workplace safety and economic development.

WikiPathways

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WikiPathways was established to facilitate the contribution and maintenance of pathway information by the biology community. WikiPathways is an open, collaborative platform dedicated to the curation of biological pathways. WikiPathways thus presents a new model for pathway databases that enhances and complements ongoing efforts, such as KEGG, Reactome and Pathway Commons. Building on the same MediaWiki software that powers Wikipedia, we added a custom graphical pathway editing tool and integrated databases covering major gene, protein, and small-molecule systems. The familiar web-based format of WikiPathways greatly reduces the barrier to participate in pathway curation. More importantly, the open, public approach of WikiPathways allows for broader participation by the entire community, ranging from students to senior experts in each field. This approach also shifts the bulk of peer review, editorial curation, and maintenance to the community.

IAGOS Data Centre

In-service Aircraft for a Global Observing System

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IAGOS aims to provide long-term, regular and spatially resolved in situ observations of the atmospheric composition. The observation systems are deployed on a fleet of 10 to 15 commercial aircraft measuring atmospheric chemistry concentrations and meteorological fields. The IAGOS Data Centre manages and gives access to all the data produced within the project.

Dementias Platform UK Data Portal

DPUK Data Portal

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The DPUK Data Portal brings together records of over 2 million people in a free-to-access resource. Researchers can identify which cohorts are relevant to them, apply for access to the data and then analyse it in a secure, remote environment with a complete data linkage and analysis package.

DASSH - The Archive for Marine Species and Habitats Data

Data Archive for Seabed Species and Habitats

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Accredited through the MEDIN partnership, and core-funded by the Department for the Environment, Food and Rural Affairs (Defra) and the Scottish Government, DASSH provides tools and services for the long-term curation, management and publication of marine species and habitats data, within the UK and internationally. Working closely with partners and data providers we are committed to the FAIR Data Principles, to make marine biodiversity data Findable, Accessible, Interoperable and Reusable. DASSH is a flagship initiative of the Marine Biological Association (MBA), and builds on the MBA's historic role in marine science. Through partnerships with other UK and European data centres DASSH contributes to data portals including the NBN Atlas, EMODnet, EurOBIS and GBIF. On an international scale DASSH is also the UK node of the Ocean Biogeographic Information System (OBIS), and an Associated Data Unit of the International Oceanographic Data and Information Exchange (IODE), giving the Data Archive Centre global recognition.

UCD Digital Library

An Leabharlann, An Coláiste Ollscoile, Baile Átha Cliath

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The UCD Digital Library is a platform for exploring cultural heritage, engaging with digital scholarship, and accessing research data. The UCD Digital Library allows you to search, browse and explore a growing collection of historical materials, photographs, art, interviews, letters, and other exciting content, that have been digitised and made freely available.

The Cambridge Structural Database

CSD

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Established in 1965, the CSD is the world’s repository for small-molecule organic and metal-organic crystal structures. Containing the results of over one million x-ray and neutron diffraction analyses this unique database of accurate 3D structures has become an essential resource to scientists around the world. The CSD records bibliographic, chemical and crystallographic information for:organic molecules, metal-organic compounds whose 3D structures have been determined using X-ray diffraction, neutron diffraction. The CSD records results of: single crystal studies, powder diffraction studies which yield 3D atomic coordinate data for at least all non-H atoms. In some cases the CCDC is unable to obtain coordinates, and incomplete entries are archived to the CSD. The CSD includes crystal structure data arising from: publications in the open literature and Private Communications to the CSD (via direct data deposition). The CSD contains directly deposited data that are not available anywhere else, known as CSD Communications.

UniProtKB

UniProtKnowledgebase

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The UniProt Knowledgebase (UniProtKB) is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation. In addition to capturing the core data mandatory for each UniProtKB entry (mainly, the amino acid sequence, protein name or description, taxonomic data and citation information), as much annotation information as possible is added. This includes widely accepted biological ontologies, classifications and cross-references, and clear indications of the quality of annotation in the form of evidence attribution of experimental and computational data. The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc). The UniProt Metagenomic and Environmental Sequences (UniMES) database is a repository specifically developed for metagenomic and environmental data. The UniProt Knowledgebase,is an expertly and richly curated protein database, consisting of two sections called UniProtKB/Swiss-Prot and UniProtKB/TrEMBL.

UK Data Service

UKDS

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The UK Data Service is a national data service funded by the ESRC to provide research access to the UK’s largest collection of social, economic and population data including UK government-sponsored surveys, cross-national surveys, longitudinal studies, UK census data, international aggregate, business data, and qualitative data. Designed to meet the data needs of researchers, students and teachers from all sectors, including academia, central and local government, charities and foundations, independent research centres, think tanks, business consultants and analysts, communities and the commercial sector, the UK Data Service provides access to high-quality social and economic data; support for policy-relevant research; guidance and training for the development of skills in data use, and the development of best practice in digital preservation and sharing. Data users can browse collections online and register to analyse and download them. Open Data collections are available for anyone to use. Key partners include JISC, the University of Manchester, University of Southampton, University of Leeds, University of Edinburgh and University College London (UCL). The lead partner is the UK Data Archive (https://service.re3data.org/repository/r3d100010215) based at the University of Essex, a Trusted Digital Repository (TDR) certified against the CoreTrustSeal (https://www.coretrustseal.org/) and certified against ISO27001 for Information Security (https://www.iso.org/standard/27001). The UK Data Service replaces the earlier ESRC investments of the Economic and Social Data Service (ESDS), the Secure Data Service (SDS), the Survey Question Bank and elements of the ESRC Census Programme.

EchoBase

an integrated post-genomic database for E.coli

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EchoBase is a database that curates new experimental and bioinformatic information about the genes and gene products of the model bacterium Escherichia coli K-12 strain MG1655.