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Found 5 result(s)

International Mouse Phenotyping Consortium

IMPC

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The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.

IntAct

IntAct Molecular Interaction Database

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IntAct provides a freely available, open source database system and analysis tools for molecular interaction data. All interactions are derived from literature curation or direct user submissions and are freely available.

HunCLARIN

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HunCLARIN is a strategic research infrastructure of Hungary’s leading knowledge centres involved in R&D in speech- and language processing. It contains linguistic resources and tools that form the basis of research. The infrastructure has obtained an “SKI” qualification (Strategic Research Infrastructure) in 2010, and has been significantly expanded since. Currently comprising 36 members, the infrastructure includes several general- and specific-purpose text corpora, different language processing tools and analysers, linguistic databases as well as ontologies. RIL HAS was a co-founder of the European CLARIN project, which aims at supporting humanities and social sciences research with the help of language technology and by making digital linguistic resources more easily available. In accordance with these goals HunClarin makes the research infrastructures developed by the respective centres directly accessible for researchers through a common network entry point. A general goal of the infrastructure is to realise the interoperability of the collected research infrastructures and to enable comparing the performance of the respective alternatives and to coordinate different foci in R&D. The coordinator and contact person of the infrastructure is Tamás Váradi, RIL HAS.

CLARIN-PL

Language Technology Centre

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Polish CLARIN node – CLARIN-PL Language Technology Centre – is being built at Wrocław University of Technology. The LTC is addressed to scholars in the humanities and social sciences. Registered users are granted free access to digital language resources and advanced tools to explore them. They can also archive and share their own language data (in written, spoken, video or multimodal form).

TwinsUK

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The TwinsUK resource is the biggest UK adult twin registry of 14.000 twins used to study the genetic and environmental aetiology of age related complex traits and diseases.