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Found 23 result(s)
OrthoMCL is a genome-scale algorithm for grouping orthologous protein sequences. It provides not only groups shared by two or more species/genomes, but also groups representing species-specific gene expansion families. So it serves as an important utility for automated eukaryotic genome annotation. OrthoMCL starts with reciprocal best hits within each genome as potential in-paralog/recent paralog pairs and reciprocal best hits across any two genomes as potential ortholog pairs. Related proteins are interlinked in a similarity graph. Then MCL (Markov Clustering algorithm,Van Dongen 2000; www.micans.org/mcl) is invoked to split mega-clusters. This process is analogous to the manual review in COG construction. MCL clustering is based on weights between each pair of proteins, so to correct for differences in evolutionary distance the weights are normalized before running MCL.
ToxoDB is a genome database for the genus Toxoplasma, a set of single-celled eukaryotic pathogens that cause human and animal diseases, including toxoplasmosis.
FungiDB belongs to the EuPathDB family of databases and is an integrated genomic and functional genomic database for the kingdom Fungi. FungiDB was first released in early 2011 as a collaborative project between EuPathDB and the group of Jason Stajich (University of California, Riverside). At the end of 2015, FungiDB was integrated into the EuPathDB bioinformatic resource center. FungiDB integrates whole genome sequence and annotation and also includes experimental and environmental isolate sequence data. The database includes comparative genomics, analysis of gene expression, and supplemental bioinformatics analyses and a web interface for data-mining.
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The Repositori Ilmiah Nasional (RIN) is a means for storing, preserving, citing, analyzing and sharing research data. RIN acts as an online media in managing, storing and sharing research data. Researchers, data writers, publishers, data distributors, and affiliated institutions all receive academic credit and web visibility. Researchers, agencies, and funders have full control over research data.
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nmrXiv is an open, FAIR and consensus-driven NMR spectroscopy data repository and analysis platform. We archive raw and processed NMR data, providing support for browsing, search, analysis, and dissemination of NMR data worldwide.
Giardia lamblia is a significant, environmentally transmitted, human pathogen and an amitochondriate protist. It is a major contributor to the enormous worldwide burden of human diarrheal diseases, yet the basic biology of this parasite is not well understood. No virulence factor has been identified. The Giardia lamblia genome contains only 12 million base pairs distributed onto five chromosomes. Its analysis promises to provide insights about the origins of nuclear genome organization, the metabolic pathways used by parasitic protists, and the cellular biology of host interaction and avoidance of host immune systems. Since the divergence of Giardia lamblia lies close to the transition between eukaryotes and prokaryotes in universal ribosomal RNA phylogenies, it is a valuable, if not unique, model for gaining basic insights into genetic innovations that led to formation of eukaryotic cells. In evolutionary terms, the divergence of this organism is at least twice as ancient as the common ancestor for yeast and man. A detailed study of its genome will provide insights into an early evolutionary stage of eukaryotic chromosome organization as well as other aspects of the prokaryotic / eukaryotic divergence.
The EUR Data Repository [EDR] is the institutional data repository from the Erasmus University Rotterdam. The EUR Data Repository is an online platform where you showcase your research and make it findable, citable, and reusable for others.
VectorBase provides data on arthropod vectors of human pathogens. Sequence data, gene expression data, images, population data, and insecticide resistance data for arthropod vectors are available for download. VectorBase also offers genome browser, gene expression and microarray repository, and BLAST searches for all VectorBase genomes. VectorBase Genomes include Aedes aegypti, Anopheles gambiae, Culex quinquefasciatus, Ixodes scapularis, Pediculus humanus, Rhodnius prolixus. VectorBase is one the Bioinformatics Resource Centers (BRC) projects which is funded by National Institute of Allergy and Infectious Diseases (NAID).
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Borealis, the Canadian Dataverse Repository, is a bilingual, multidisciplinary, secure, Canadian research data repository, supported by academic libraries and research institutions across Canada. Borealis supports open discovery, management, sharing, and preservation of Canadian research data. Borealis is available to researchers who are affiliated with a participating Canadian university or research organization and their collaborators. Borealis is a shared service provided in partnership with Canadian regional academic library consortia, institutions, research organizations, and the Digital Research Alliance of Canada, with technical infrastructure hosted by Scholars Portal and the University of Toronto Libraries.
The mission of World Data Center for Climate (WDCC) is to provide central support for the German and European climate research community. The WDCC is member of the ISC's World Data System. Emphasis is on development and implementation of best practice methods for Earth System data management. Data for and from climate research are collected, stored and disseminated. The WDCC is restricted to data products. Cooperations exist with thematically corresponding data centres of, e.g., earth observation, meteorology, oceanography, paleo climate and environmental sciences. The services of WDCC are also available to external users at cost price. A special service for the direct integration of research data in scientific publications has been developed. The editorial process at WDCC ensures the quality of metadata and research data in collaboration with the data producers. A citation code and a digital identifier (DOI) are provided and registered together with citation information at the DOI registration agency DataCite.
B2SHARE is a user-friendly, reliable and trustworthy way for researchers, scientific communities and citizen scientists to store and share small-scale research data from diverse contexts and disciplines. B2SHARE is able to add value to your research data via (domain tailored) metadata, and assigning citable Persistent Identifiers PIDs (Handles) to ensure long-lasting access and references. B2SHARE is one of the B2 services developed via EUDAT and long tail data deposits do not cost money. Special arrangements such as branding and special metadata elements can be made on request.
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The MDR harvests metadata on data objects from a variety of sources within clinical research (e.g. trial registries, data repositories) and brings that together in a single searchable portal. The metadata is concerned with discoverability, access and provenance of the data objects (which because the data may be sensitive will often be available under a controlled access regime). At the moment (01/2021) the MDR obtains study data from: Clinical Trials.gov (CTG), The European Clinical Trials Registry (EUCTR), ISRCTN, The WHO ICTRP
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This repository accepts data from life science researchers and service units in Sweden. The repository is operated by SciLifeLab, which is the national infrastructure for life science and environmental research in Sweden. This repository replaces NBIS DOI repository: https://doi.org/10.17616/R3CW52
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The Open Energy Family aims to ensure quality, transparency and reproducibility in energy system research. It is a collection of various tools and information and that help working with energy related data. It is a collaborative community effort, everything is openly developed and therefore constantly evolving. The main module is the Open Energy Platform (OEP), a web interface to access most of the modules, especially the community database. It provides a way to publish data with proper documentation (metadata), and link it to source code and underlying assumptions. Open Energy Database is an open community database for energy, climate and modelling data.
The Immunology Database and Analysis Portal (ImmPort) archives clinical study and trial data generated by NIAID/DAIT-funded investigators. Data types housed in ImmPort include subject assessments i.e., medical history, concomitant medications and adverse events as well as mechanistic assay data such as flow cytometry, ELISA, ELISPOT, etc. --- You won't need an ImmPort account to search for compelling studies, peruse study demographics, interventions and mechanistic assays. But why stop there? What you really want to do is download the study, look at each experiment in detail including individual ELISA results and flow cytometry files. Perhaps you want to take those flow cytometry files for a test drive using FLOCK in the ImmPort flow cytometry module. To download all that interesting data you will need to register for ImmPort access.
EuPathDB (formerly ApiDB) is an integrated database covering the eukaryotic pathogens in the genera Acanthamoeba, Annacaliia, Babesia, Crithidia, Cryptosporidium, Edhazardia, Eimeria, Encephalitozoon, Endotrypanum, Entamoeba, Enterocytozoon, Giardia, Gregarina, Hamiltosporidium, Leishmania, Nematocida, Neospora, Nosema, Plasmodium, Theileria, Toxoplasma, Trichomonas, Trypanosoma and Vavraia, Vittaforma). While each of these groups is supported by a taxon-specific database built upon the same infrastructure, the EuPathDB portal offers an entry point to all of these resources, and the opportunity to leverage orthology for searches across genera.
Content type(s)
A genome database for the genus Piroplasma. PiroplasmaDB is a member of pathogen-databases that are housed under the NIAID-funded EuPathDB Bioinformatics Resource Center (BRC) umbrella.
ZENODO builds and operates a simple and innovative service that enables researchers, scientists, EU projects and institutions to share and showcase multidisciplinary research results (data and publications) that are not part of the existing institutional or subject-based repositories of the research communities. ZENODO enables researchers, scientists, EU projects and institutions to: easily share the long tail of small research results in a wide variety of formats including text, spreadsheets, audio, video, and images across all fields of science. display their research results and get credited by making the research results citable and integrate them into existing reporting lines to funding agencies like the European Commission. easily access and reuse shared research results.