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This project is an open invitation to anyone and everyone to participate in a decentralized effort to explore the opportunities of open science in neuroimaging. We aim to document how much (scientific) value can be generated from a data release — from the publication of scientific findings derived from this dataset, algorithms and methods evaluated on this dataset, and/or extensions of this dataset by acquisition and incorporation of new data. The project involves the processing of acoustic stimuli. In this study, the scientists have demonstrated an audiodescription of classic "Forrest Gump" to subjects, while researchers using functional magnetic resonance imaging (fMRI) have captured the brain activity of test candidates in the processing of language, music, emotions, memories and pictorial representations.In collaboration with various labs in Magdeburg we acquired and published what is probably the most comprehensive sample of brain activation patterns of natural language processing. Volunteers listened to a two-hour audio movie version of the Hollywood feature film "Forrest Gump" in a 7T MRI scanner. High-resolution brain activation patterns and physiological measurements were recorded continuously. These data have been placed into the public domain, and are freely available to the scientific community and the general public.
The UniPROBE (Universal PBM Resource for Oligonucleotide Binding Evaluation) database hosts data generated by universal protein binding microarray (PBM) technology on the in vitro DNA binding specificities of proteins. This initial release of the UniPROBE database provides a centralized resource for accessing comprehensive data on the preferences of proteins for all possible sequence variants ('words') of length k ('k-mers'), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In total, the database currently hosts DNA binding data for 406 nonredundant proteins from a diverse collection of organisms, including the prokaryote Vibrio harveyi, the eukaryotic malarial parasite Plasmodium falciparum, the parasitic Apicomplexan Cryptosporidium parvum, the yeast Saccharomyces cerevisiae, the worm Caenorhabditis elegans, mouse, and human. The database's web tools (on the right) include a text-based search, a function for assessing motif similarity between user-entered data and database PWMs, and a function for locating putative binding sites along user-entered nucleotide sequences
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The Small Molecule Pathway Database (SMPDB) contains small molecule pathways found in humans, which are presented visually. All SMPDB pathways include information on the relevant organs, subcellular compartments, protein cofactors, protein locations, metabolite locations, chemical structures and protein quaternary structures. Accompanying data includes detailed descriptions and references, providing an overview of the pathway, condition or processes depicted in each diagram.
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The version 1.0 of the open database contains 1,151,268 brain signals of 2 seconds each, captured with the stimulus of seeing a digit (from 0 to 9) and thinking about it, over the course of almost 2 years between 2014 & 2015, from a single Test Subject David Vivancos. All the signals have been captured using commercial EEGs (not medical grade), NeuroSky MindWave, Emotiv EPOC, Interaxon Muse & Emotiv Insight, covering a total of 19 Brain (10/20) locations. In 2014 started capturing brain signals and released the first versions of the "MNIST" of brain digits, and in 2018 released another open dataset with a subset of the "IMAGENET" of The Brain. Version 0.05 (last update 09/28/2021) of the open database contains 24,000 brain signals of 2 seconds each, captured with the stimulus of seeing a real MNIST digit (from 0 to 9) 6,000 so far and thinking about it, + the same amout of signals with another 2 seconds of seeing a black screen, shown in between the digits, from a single Test Subject David Vivancos in a controlled still experiment to reduce noise from EMG & avoiding blinks.
The RESID Database of Protein Modifications is a comprehensive collection of annotations and structures for protein modifications including amino-terminal, carboxyl-terminal and peptide chain cross-link post-translational modifications.