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Found 816 result(s)
ClinVar is a freely accessible, public archive of reports of the relationships among human variations and phenotypes, with supporting evidence. ClinVar thus facilitates access to and communication about the relationships asserted between human variation and observed health status, and the history of that interpretation. ClinVar processes submissions reporting variants found in patient samples, assertions made regarding their clinical significance, information about the submitter, and other supporting data. The alleles described in submissions are mapped to reference sequences, and reported according to the HGVS standard. ClinVar then presents the data for interactive users as well as those wishing to use ClinVar in daily workflows and other local applications. ClinVar works in collaboration with interested organizations to meet the needs of the medical genetics community as efficiently and effectively as possible
Surface air temperature change is a primary measure of global climate change. The GISTEMP project started in the late 1970s to provide an estimate of the changing global surface air temperature which could be compared with the estimates obtained from climate models simulating the effect of changes in atmospheric carbon dioxide, volcanic aerosols, and solar irradiance. The continuing analysis updates global temperature change from the late 1800s to the present.
All ADNI data are shared without embargo through the LONI Image and Data Archive (IDA), a secure research data repository. Interested scientists may obtain access to ADNI imaging, clinical, genomic, and biomarker data for the purposes of scientific investigation, teaching, or planning clinical research studies. "The Alzheimer’s Disease Neuroimaging Initiative (ADNI) unites researchers with study data as they work to define the progression of Alzheimer’s disease (AD). ADNI researchers collect, validate and utilize data, including MRI and PET images, genetics, cognitive tests, CSF and blood biomarkers as predictors of the disease. Study resources and data from the North American ADNI study are available through this website, including Alzheimer’s disease patients, mild cognitive impairment subjects, and elderly controls. "
The Alternative Fuels Data Center (AFDC) is a comprehensive clearinghouse of information about advanced transportation technologies. The AFDC offers transportation decision makers unbiased information, data, and tools related to the deployment of alternative fuels and advanced vehicles. The AFDC launched in 1991 in response to the Alternative Motor Fuels Act of 1988 and the Clean Air Act Amendments of 1990. It originally served as a repository for alternative fuel performance data. The AFDC has since evolved to offer a broad array of information resources that support efforts to reduce petroleum use in transportation. The AFDC serves Clean Cities stakeholders, fleets regulated by the Energy Policy Act, businesses, policymakers, government agencies, and the general public.
The Seamount Catalog is a digital archive for bathymetric seamount maps from all the oceans that can be viewed and downloaded in various formats. This catalog contains morphological data, sample information, related grid and multibeam data files, as well as user-contributed files that all can be downloaded.
The International Union of Basic and Clinical Pharmacology (IUPHAR) / British Pharmacological Society (BPS) Guide to PHARMACOLOGY is an expert-curated resource of ligand-activity-target relationships, the majority of which come from high-quality pharmacological and medicinal chemistry literature. It is intended as a “one-stop shop” portal to pharmacological information and its main aim is to provide a searchable database with quantitative information on drug targets and the prescription medicines and experimental drugs that act on them. In future versions we plan to add resources for education and training in pharmacological principles and techniques along with research guidelines and overviews of key topics. We hope that the IUPHAR/BPS Guide to PHARMACOLOGY (abbreviated as GtoPdb) will be useful for researchers and students in pharmacology and drug discovery and provide the general public with accurate information on the basic science underlying drug action.
The information in the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer relates cytogenetic changes and their genomic consequences, in particular gene fusions, to tumor characteristics, based either on individual cases or associations. All the data have been manually culled from the literature by Felix Mitelman in collaboration with Bertil Johansson and Fredrik Mertens.
The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.
Pubchem contains 3 databases. 1. PubChem BioAssay: The PubChem BioAssay Database contains bioactivity screens of chemical substances described in PubChem Substance. It provides searchable descriptions of each bioassay, including descriptions of the conditions and readouts specific to that screening procedure. 2. PubChem Compound: The PubChem Compound Database contains validated chemical depiction information provided to describe substances in PubChem Substance. Structures stored within PubChem Compounds are pre-clustered and cross-referenced by identity and similarity groups. 3. PubChem Substance. The PubChem Substance Database contains descriptions of samples, from a variety of sources, and links to biological screening results that are available in PubChem BioAssay. If the chemical contents of a sample are known, the description includes links to PubChem Compound.
The OpenMadrigal project seeks to develop and support an on-line database for geospace data. The project has been led by MIT Haystack Observatory since 1980, but now has active support from Jicamarca Observatory and other community members. Madrigal is a robust, World Wide Web based system capable of managing and serving archival and real-time data, in a variety of formats, from a wide range of ground-based instruments. Madrigal is installed at a number of sites around the world. Data at each Madrigal site is locally controlled and can be updated at any time, but shared metadata between Madrigal sites allow searching of all Madrigal sites at once from any Madrigal site. Data is local; metadata is shared.
The Deep Blue Data repository is a means for University of Michigan researchers to make their research data openly accessible to anyone in the world, provided they meet collections criteria. Submitted data sets undergo a curation review by librarians to support discovery, understanding, and reuse of the data.
The Supreme Court Database is the definitive source for researchers, students, journalists, and citizens interested in the U.S. Supreme Court. The Database contains over two hundred pieces of information about each case decided by the Court between the 1791 and 2015 terms. Examples include the identity of the court whose decision the Supreme Court reviewed, the parties to the suit, the legal provisions considered in the case, and the votes of the Justices. The project started with Spaeth's original database. The analysis tools allow you to select and summarize cases from the Modern or Legacy Database based on your needs.
The University of Toronto Dataverse is a research data repository for our faculty, students, and staff. Files are held in a secure environment on Canadian servers. Researchers can choose to make content available publicly, to specific individuals, or to restrict access.
LEPR is a database of results of published experimental studies involving liquid-solid phase equilibria relevant to natural magmatic systems. TraceDs is a database of experimental studies involving trace element distribution between liquid, solid and fluid phases.
<<<!!!<<< the repository is offline >>>!!!<<< NARSTO is dedicated to improving management of air quality in North America. Additionally, NARSTO is working to improve collaboration between the air-quality and health-sciences research communities, to advance understanding of the scientific issues involved in effecting a multi-pollutant/multi-media approach to air quality management, and to increase understanding of the linkages between air quality and climate change. NARSTO is represented by private and public organizations in Canada, Mexico, and the United States. NARSTO was terminated as of December 31, 2010. While data remain available via the original NARSTO Data Archive, the permanent data archive is maintained by the NASA Langley Research Center Atmospheric Science Data Center
<<<!!!<<< 2019-01: Global Land Cover Facility goes offline see https://spatialreserves.wordpress.com/2019/01/07/global-land-cover-facility-goes-offline/ ; no more access to http://www.landcover.org >>>!!!>>> The Global Land Cover Facility (GLCF) provides earth science data and products to help everyone to better understand global environmental systems. In particular, the GLCF develops and distributes remotely sensed satellite data and products that explain land cover from the local to global scales.
The Chandra Data Archive (CDA) plays a central role in the operation of the Chandra X-ray Center (CXC) by providing support to the astronomical community in accessing Chandra data. Its primary role is one of storage and distribution of all data products including those that users of the observatory need to perform their scientific studies using Chandra data. The CDA offers access to digital archives through powerful query engines, including VO-compliant interfaces. The CDA also serves as a permanent storage repository of contributed data products by authors who have processed images or other pertinent and valuable datasets that are essential to their publications.
<<<!!!<<< This repository is no longer available. This record is out-dated >>>!!!>>> The ONS challenge contains open solubility data, experiments with raw data from different scientists and institutions. It is part of the The Open Notebook Science wiki community, ideally suited for community-wide collaborative research projects involving mathematical modeling and computer simulation work, as it allows researchers to document model development in a step-by-step fashion, then link model prediction to experiments that test the model, and in turn, use feeback from experiments to evolve the model. By making our laboratory notebooks public, the evolutionary process of a model can be followed in its totality by the interested reader. Researchers from laboratories around the world can now follow the progress of our research day-to-day, borrow models at various stages of development, comment or advice on model developments, discuss experiments, ask questions, provide feedback, or otherwise contribute to the progress of science in any manner possible.
<<<!!!<<< 2019-12-04: The repository is no longer available >>>!!!>>> Presented here are excitation cross sections measured for a select number of transitions using the Merged Electron-Ion Beams Energy Loss (MEIBEL) experiment. This is a collaboration of JILA and the Multicharged Ion Research Facility (MIRF) at Oak Ridge National Laboratory (ORNL), where the apparatus is located. Since there exist a nearly infinite number of transitions in multicharged ions we have chosen a few that serve as benchmarks for theoretical efforts. Of particular interest are forbidden transitions which are often dominated by dielectronic resonances whose positions and magnitudes are difficult to predict theoretically.
<<<!!!<<< The repository is no longer available. >>>!!!>>> 2021-06-17; VentDB data collections now housed in the EarthChem Library VentDB is an effort funded by the US National Science Foundation to build and operate a data management system for hydrothermal spring geochemistry that will host and serve the full range of compositional data acquired on seafloor hydrothermal vents from all tectonic settings. VentDB supports the preservation and dissemination of analytical data on hydrothermal springs and plumes. VentDB complements existing geochemical data collections such as SedDB and PetDB. VentDB can accommodate published historical data as well as legacy and new data that investigators contribute. Content of VentDB is static and will not be updated until further notice.
Project Data Sphere, LLC, operates a free digital library-laboratory where the research community can broadly share, integrate and analyze historical, de-identified, patient-level data from academic and industry cancer Phase II-III clinical trials. These patient-level datasets are available through the Project Data Sphere platform to researchers affiliated with life science companies, hospitals and institutions, as well as independent researchers, at no cost and without requiring a research proposal.
<<<!!!<<< The repository is no longer available. >>>!!!>>> Here you will find a collection of atomic microstructures that have been built by the atomic modeling community. Feel free to download any of these and use them in your own scientific explorations.The focus of this cyberinfrastructure is to advance the field of atomic-scale modeling of materials by acting as a forum for disseminating new atomistic scale methodologies, educating non-experts and the next generation of computational materials scientists, and serving as a bridge between the atomistic and complementary (electronic structure, mesoscale) modeling communities.
BSRN is a project of the Radiation Panel (now the Data and Assessment Panel) from the Global Energy and Water Cycle Experiment (GEWEX) under the umbrella of the World Climate Research Programme (WCRP). It is the global baseline network for surface radiation for the Global limate Observing System (GCOS), contributing to the Global Atmospheric Watch (GAW), and forming a ooperative network with the Network for the Detection of Atmospheric Composition Change NDACC).