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Found 129 result(s)
BioGRID ORCS is an open repository of CRISPR screens compiled through comprehensive curation efforts. The current index is version 1.0.3 and searches more than 49 publications and 58,161 genes to return more than 895 CRISPR screens from 3 major model organism species and 629 cell lines. All screen data are freely provided through our search index and available via download in a wide variety of standardized formats.
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<<<!!!<<< 2017-06-02: We recently suffered a server failure and are working to bring the full ORegAnno website back online. In the meantime, you may download the complete database here: http://www.oreganno.org/dump/ ; Data are also available through UCSC Genome Browser (e.g., hg38 -> Regulation -> ORegAnno) https://genome.ucsc.edu/cgi-bin/hgTrackUi?hgsid=686342163_2it3aVMQVoXWn0wuCjkNOVX39wxy&c=chr1&g=oreganno >>>!!!>>> The Open REGulatory ANNOtation database (ORegAnno) is an open database for the curation of known regulatory elements from scientific literature. Annotation is collected from users worldwide for various biological assays and is automatically cross-referenced against PubMED, Entrez Gene, EnsEMBL, dbSNP, the eVOC: Cell type ontology, and the Taxonomy database, where appropriate, with information regarding the original experimentation performed (evidence). ORegAnno further provides an open validation process for all regulatory annotation in the public domain. Assigned validators receive notification of new records in the database and are able to cross-reference the citation to ensure record integrity. Validators have the ability to modify any record (deprecating the old record and creating a new one) if an error is found. Further, any contributor to the database can comment on any annotation by marking errors, or adding special reports into function as they see fit. These features of ORegAnno ensure that the collection is of the highest quality and uniquely provides a dynamic view of our changing understanding of gene regulation in the various genomes.
SuperDARN is an international HF radar network designed to measure global-scale magnetospheric convection by observing plasma motion in the Earth’s upper atmosphere. This network consists of more than 20 radars operating on frequencies between 8 and 20 MHz that look into the polar regions of Earth. These radars can measure the position and velocity of charged particles in our ionosphere, the highest layer of the Earth's atmosphere, and provide scientists with information regarding Earth's interaction with the space environment.
OrtholugeDB contains Ortholuge-based orthology predictions for completely sequenced bacterial and archaeal genomes. It is also a resource for reciprocal best BLAST-based ortholog predictions, in-paralog predictions (recently duplicated genes) and ortholog groups in Bacteria and Archaea. The Ortholuge method improves the specificity of high-throughput orthology prediction.
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The goals of FMGP are to: (i) sequence complete mitochondrial genomes from all major fungal lineages, (ii) infer a robust fungal phylogeny, (iii) define the origin of the fungi, their protistan ancestors, and their specific phylogenetic link to the animals, (iv) investigate mitochondrial gene expression, introns, RNAse P RNA structures, mobile elements.
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The Canadian Open Genetics Repository is a collaborative effort for the collection, storage, sharing and robust analysis of variants reported by medical diagnostics laboratories across Canada. As clinical laboratories adopt modern genomics technologies, the need for this type of collaborative framework is increasingly important. If you want to join COGR project and get data please send an email at cogr@opengenetics.ca and the introduction to the project will be arranged.
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Launched in November 1995, RADARSAT-1 provided Canada and the world with an operational radar satellite system capable of timely delivery of large amounts of data. Equipped with a powerful synthetic aperture radar (SAR) instrument, it acquired images of the Earth day or night, in all weather and through cloud cover, smoke and haze. RADARSAT-1 was a Canadian-led project involving the Canadian federal government, the Canadian provinces, the United States, and the private sector. It provided useful information to both commercial and scientific users in such fields as disaster management, interferometry, agriculture, cartography, hydrology, forestry, oceanography, ice studies and coastal monitoring. In 2007, RADARSAT-2 was launched, producing over 75,000 images per year since. In 2019, the RADARSAT Constellation Mission was deployed, using its three-satellite configuration for all-condition coverage. More information about RADARSAT-2 see https://mda.space/en/geo-intelligence/ RADARSAT-2 PORTAL see https://gsiportal.mda.space/gc_cp/#/map
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Reptiles and amphibians are collectively known as herpetofauna and are a unique part of Ontario’s biodiversity. An earlier atlas, called the Ontario Herpetofaunal Summary Atlas, provided extensive information about where many of the province’s reptiles and amphibians occurred. The Atlas is transitioning into a new era, with Ontario Nature wrapping-up the data collection phase of this project as of December 1, 2019. Now that we have discontinued our app and online form, we encourage you to continue submitting any future observations through the ‘Herps of Ontario’ project (https://www.inaturalist.org/projects/herps-of-ontario) on iNaturalist or directly to the Natural Heritage Information Centre (nhicrequests@ontario.ca) for species at risk. To learn more about the transition, read our blog (https://ontarionature.org/ontario-reptile-and-amphibian-atlas-changes/)
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The Small Molecule Pathway Database (SMPDB) contains small molecule pathways found in humans, which are presented visually. All SMPDB pathways include information on the relevant organs, subcellular compartments, protein cofactors, protein locations, metabolite locations, chemical structures and protein quaternary structures. Accompanying data includes detailed descriptions and references, providing an overview of the pathway, condition or processes depicted in each diagram.
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The CCDS is an interface for distributing climate change information. The goals of CCDS are to: Support climate change impact and adaptation research in Canada and other countries; Support stakeholders requiring scenario information for decision making and policy development. Provide access to Canadian research on the development of scenarios and adaptation research.
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The Northwest Territories (NWT) Species Infobase is a searchable catalogue of referenced information on NWT species. It includes the information on habitat, distribution, population numbers, trends and threats used to rank the general status of NWT species.
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Historical Climate Data (formerly: The National Climate Data and Information Archive - NCDC) is a web-based resource maintained by Environment and Climate Change Canada and the Meteorological Service of Canada. The site houses a number of statistical and data compilation and viewing tools. From the website, users can access historical climate data for Canadian locations and dates, view climate normals and averages, and climate summaries. A list of Canadian air stations and their meteorological reports and activities is also available, along with rainfall statistics for more than 500 locations across Canada. Users can also download the Canadian daily climate data for 2006/07. In addition, technical documentation is offered for data users to interpret the available data. Other documentation includes a catalogue of Canadian weather reporting stations, a glossary, and a calculation of the 1971 to 2000 climate normals for Canada. This resource carries authority and accuracy because it is maintained by a national government department and service. While the majority of the statistics are historical, the data is up-to-date and contains current and fairly recent climate data. This government resource is intended for an audience that has the ability and knowledge to interpret climatological data
The CONP portal is a web interface for the Canadian Open Neuroscience Platform (CONP) to facilitate open science in the neuroscience community. CONP simplifies global researcher access and sharing of datasets and tools. The portal internalizes the cycle of a typical research project: starting with data acquisition, followed by processing using already existing/published tools, and ultimately publication of the obtained results including a link to the original dataset. From more information on CONP, please visit https://conp.ca
OSGeo's mission is to support the collaborative development of open source geospatial software, in part by providing resources for projects and promoting freely available geodata. The Public Geodata Repository is a distributed repository and registry of data sources free to access, reuse, and re-distribute.
The USGS Alaska Region has the largest geographic extent of the seven regional units within the USGS and represents a dynamic landscape of great natural wonder. It is a transforming landscape shaped by volcanoes, earthquakes, major rivers, and glaciers and a strategic landscape of yet untapped mineral and energy resources. The Region conducts research to help inform management of the extensive national parks and wildlife refuges of the far north and the international birds, fish, and marine mammals that migrate to these lands and waters; informs national Arctic energy policy through research on the National Petroleum Reserve-Alaska and the U.S. Outer Continental Shelf; and provides science to understand, help respond to and mitigate impacts from natural hazards. This work is accomplished in part by the Region's two Science Centers headquartered in Anchorage, the Alaska Science Center and the Volcano Science Center.
InnateDB is a publicly available database of the genes, proteins, experimentally-verified interactions and signaling pathways involved in the innate immune response of humans, mice and bovines to microbial infection. The database captures an improved coverage of the innate immunity interactome by integrating known interactions and pathways from major public databases together with manually-curated data into a centralised resource. The database can be mined as a knowledgebase or used with our integrated bioinformatics and visualization tools for the systems level analysis of the innate immune response.
Biological collections are replete with taxonomic, geographic, temporal, numerical, and historical information. This information is crucial for understanding and properly managing biodiversity and ecosystems, but is often difficult to access. Canadensys, operated from the Université de Montréal Biodiversity Centre, is a Canada-wide effort to unlock the biodiversity information held in biological collections.
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BACTIBASE contains calculated or predicted physicochemical properties of bacteriocins produced by both Gram-positive and Gram-negative bacteria. The information in this database is very easy to extract and allows rapid prediction of relationships structure/function and target organisms of these peptides and therefore better exploitation of their biological activity in both the medical and food sectors.
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Ocean Networks Canada maintains several observatories installed in three different regions in the world's oceans. All three observatories are cabled systems that can provide power and high bandwidth communiction paths to sensors in the ocean. The infrastructure supports near real-time observations from multiple instruments and locations distributed across the Arctic, NEPTUNE and VENUS observatory networks. These observatories collect data on physical, chemical, biological, and geological aspects of the ocean over long time periods, supporting research on complex Earth processes in ways not previously possible.
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Primate Cell Type Database, a publicly available web-accessible archive of intracellular patch clamp recordings and highly detailed three-dimensional digital reconstructions of neuronal morphology.
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The Centre for Applied Genomics hosts a variety of databases related to ongoing supported projects. Curation of these databases is performed in-house by TCAG Bioinformatics staff. The Autism Chromosome Rearrangement Database, The Cystic Fibrosis Mutation Database, TThe Lafora Progressive Myoclonus Epilepsy Mutation and Polymorphism Database are included. Large Scale Genomics Research resources include, the Database of Genomic Variants, The Chromosome 7 Annotation Project, The Human Genome Segmental Duplication Database, and the Non-Human Segmental Duplication Database
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The Canadian Disaster Database (CDD) contains detailed disaster information on more than 1000 natural, technological and conflict events (excluding war) that have happened since 1900 at home or abroad and that have directly affected Canadians. Message since 2022-01: The Canadian Disaster Database geospatial view is temporarily out of service. We apologize for the inconvenience. The standard view of the database is still available.