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Found 61 result(s)
NetSlim is a resource of high-confidence signaling pathway maps derived from NetPath pathway reactions. 40-60% of the molecules and their reactions in NetPath pathways are available in NetSlim.
The MHKDR is the repository for all data collected using funds from the Water Power Technologies Office (WPTO) of the U.S. Department of Energy (DOE). It was established to receive, manage, and make available all water power relevant data generated from projects funded by the DOE Water Power Technologies Office. This includes data from WPTO-funded projects associated with any portion of the water power project life-cycle (exploration, development, operation), as well as data produced by WPTO-funded research.
PSnpBind is a large database of protein–ligand complexes covering a wide range of binding pocket mutations and small molecules’ landscape. This database can be used as a source of data for different types of studies, for example, developing machine learning algorithms to predict protein–ligand affinity or mutation's effect on it which requires an extensive amount of data with a wide coverage of mutation types and small molecules. Also, studies of protein-ligand interactions and conformer orientation changes across different mutated versions of a protein can be established using data from PSnpBind.
figshare allows researchers to publish all of their research outputs in an easily citable, sharable and discoverable manner. All file formats can be published, including videos and datasets. Optional peer review process. figshare uses creative commons licensing. figshare+ repository allows figshare users to share larger datasets, over 20GB up to many TBs, see: https://plus.figshare.com/
ChEMBL is a database of bioactive drug-like small molecules, it contains 2-D structures, calculated properties (e.g. logP, Molecular Weight, Lipinski Parameters, etc.) and abstracted bioactivities (e.g. binding constants, pharmacology and ADMET data). The data is abstracted and curated from the primary scientific literature, and cover a significant fraction of the SAR and discovery of modern drugs We attempt to normalise the bioactivities into a uniform set of end-points and units where possible, and also to tag the links between a molecular target and a published assay with a set of varying confidence levels. Additional data on clinical progress of compounds is being integrated into ChEMBL at the current time.
Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of 'small molecular entities'. The term 'molecular entity' encompasses any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer, etc., identifiable as a separately distinguishable entity. The molecular entities in question are either products of nature or synthetic products used to intervene in the processes of living organisms (either deliberately, as for drugs, or unintentionally', as for chemicals in the environment). The qualifier 'small' implies the exclusion of entities directly encoded by the genome, and thus as a rule nucleic acids, proteins and peptides derived from proteins by cleavage are not included.
The Marine Geoscience Data System (MGDS) is a trusted data repository that provides free public access to a curated collection of marine geophysical data products and complementary data related to understanding the formation and evolution of the seafloor and sub-seafloor. Developed and operated by domain scientists and technical specialists with deep knowledge about the creation, analysis and scientific interpretation of marine geoscience data, the system makes available a digital library of data files described by a rich curated metadata catalog. MGDS provides tools and services for the discovery and download of data collected throughout the global oceans. Primary data types are geophysical field data including active source seismic data, potential field, bathymetry, sidescan sonar, near-bottom imagery, other seafloor senor data as well as a diverse array of processed data and interpreted data products (e.g. seismic interpretations, microseismicity catalogs, geologic maps and interpretations, photomosaics and visualizations). Our data resources support scientists working broadly on solid earth science problems ranging from mid-ocean ridge, subduction zone and hotspot processes, to geohazards, continental margin evolution, sediment transport at glaciated and unglaciated margins.
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The INFRA-ART Spectral Library is an open-access integrated spectral library of artist paint materials that was designed as a digital support tool for research specialists and other heritage-related professionals that work with non- or minimally invasive spectroscopic techniques.
The GeoNames geographical database covers all countries and contains over eight million placenames that are available for download free of charge.
The Ensembl project produces genome databases for vertebrates and other eukaryotic species. Ensembl is a joint project between the European Bioinformatics Institute (EBI) and the Wellcome Trust Sanger Institute (WTSI) to develop a software system that produces and maintains automatic annotation on selected genomes.The Ensembl project was started in 1999, some years before the draft human genome was completed. Even at that early stage it was clear that manual annotation of 3 billion base pairs of sequence would not be able to offer researchers timely access to the latest data. The goal of Ensembl was therefore to automatically annotate the genome, integrate this annotation with other available biological data and make all this publicly available via the web. Since the website's launch in July 2000, many more genomes have been added to Ensembl and the range of available data has also expanded to include comparative genomics, variation and regulatory data. Ensembl is a joint project between European Bioinformatics Institute (EBI), an outstation of the European Molecular Biology Laboratory (EMBL), and the Wellcome Trust Sanger Institute (WTSI). Both institutes are located on the Wellcome Trust Genome Campus in Hinxton, south of the city of Cambridge, United Kingdom.
Atlas of the early iron age kurgans (burial mounds) of the Saks in the Land of Seven Rivers between the river Ili and the foothills of the Transili-Alatau as well as in the mountain valleys of the northern Tien-Shans.