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Library Open Access Repository (LOAR) is an open data repository established in 2016 as a service for storing and providing access to Danish research data. The service has the following key goals: Make data accessible to review for publications. Enable researchers to meet requirements for Danish and European grants. Ensure data privacy and removal of data as appropriate. Enable reuse of data where appropriate Researchers who upload data are expected to share the data using Creative Commons licenses.
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Exposures in the period from conception to early childhood - including fetal growth, cell division, and organ functioning - may have long-lasting impact on health and disease susceptibility. To investigate these issues the Danish National Birth Cohort (Better health in generations) was established. A large cohort of pregnant women with long-term follow-up of the offspring was the obvious choice because many of the exposures of interest cannot be reconstructed with suffcient validity back in time. The study needed to be large, and the aim was to recruit 100,000 women early in pregnancy, and to continue follow-up for decades. Exposure information was collected by computer-assisted telephone interviews with the women twice during pregnancy and when their children were six and 18 months old. Participants were also asked to fill in a self-administered food frequency questionnaire in mid-pregnancy. Furthermore, a biological bank has been set up with blood taken from the mother twice during pregnancy and blood from theumbilical cord taken shortly after birth.