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Found 3 result(s)

International Service of Geomagnetic Indices

ISGI

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The International Service of Geomagnetic Indices (ISGI) is in charge of the elaboration and dissemination of geomagnetic indices, and of tables of remarkable magnetic events, based on the report of magnetic observatories distributed all over the planet, with the help of ISGI Collaborating Institutes. The interaction between the solar wind, including plasma and interplanetary magnetic field, and the Earth's magnetosphere results in a transfer of energy and particles inside the magnetosphere. Solar wind characteristics are highly variable, and they have actually a direct influence on the shape and size of the magnetosphere, on the amount of transferred energy, and on the way this energy is dissipated. It is clear that the great diversity of sources of magnetic variations give rise to a great complexity in ground magnetic signatures. Geomagnetic indices aim at describing the geomagnetic activity or some of its components. Each geomagnetic index is related to different phenomena occurring in the magnetosphere, ionosphere and deep in the Earth in its own unique way. The location of a measurement, the timing of the measurement and the way the index is calculated all affect the type of phenomenon the index relates to. The IAGA endorsed geomagnetic indices and lists of remarkable geomagnetic events constitute unique temporal and spatial coverage data series homogeneous since middle of 19th century.

STITCH 4.0

Search Tool for Interactions of Chemicals

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The Database explores the interactions of chemicals and proteins. It integrates information about interactions from metabolic pathways, crystal structures, binding experiments and drug-target relationships. Inferred information from phenotypic effects, text mining and chemical structure similarity is used to predict relations between chemicals. STITCH further allows exploring the network of chemical relations, also in the context of associated binding proteins.

European Zebrafish Resource Center

EZRC

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The EZRC at KIT houses the largest experimental fish facility in Europe with a capacity of more than 300,000 fish. Zebrafish stocks are maintained mostly as frozen sperm. Frequently requested lines are also kept alive as well as a selection of wildtype strains. Several thousand mutations in protein coding genes generated by TILLING in the Stemple lab of the Sanger Centre, Hinxton, UK and lines generated by ENU mutagenesis by the Nüsslein-Volhard lab in addition to transgenic lines and mutants generated by KIT groups or brought in through collaborations. We also accept submissions on an individual basis and ship fish upon request to PIs in Europe and elsewhere. EZRC also provides screening services and technologies such as imaging and high-throughput sequencing. Key areas include automation of embryo handling and automated image acquisition and processing. Our platform also involves the development of novel microscopy techniques (e.g. SPIM, DSLM, robotic macroscope) to permit high-resolution, real-time imaging in 4D. By association with the ComPlat platform, we can support also chemical screens and offer libraries with up to 20,000 compounds in total for external users. As another service to the community the EZRC provides plasmids (cDNAs, transgenes, Talen, Crispr/cas9) maintained by the Helmholtz repository of Bioparts (HERBI) to the scientific community. In addition the fish facility keeps a range of medaka stocks, maintained by the Loosli group.