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Found 3211 result(s)
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Stemformatics is a collaboration between the stem cell and bioinformatics community. We were motivated by the plethora of exciting cell models in the public and private domains, and the realisation that for many biologists these were mostly inaccessible. We wanted a fast way to find and visualise interesting genes in these exemplar stem cell datasets. We'd like you to explore. You'll find data from leading stem cell laboratories in a format that is easy to search, easy to visualise and easy to export.
The Pacific Islands Families (PIF) Study is an ongoing longitudinal birth cohort study that has been tracking the health and development of 1,398 Pacific children and their parents since the children were born at Middlemore Hospital in South Auckland in the year 2000. It is the only prospective study specifically of Pacific peoples in the world.
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REGARDS is an observational study of risk factors for stroke in adults 45 years or older. 30,239 participants were recruited between January 2003 and October 2007. They completed a telephone interview followed by an in-home physical exam. Measurements included traditional risk factors such as blood pressure and cholesterol levels, and an echocardiogram of the heart. At six month intervals, participants are contacted by phone to ask about stroke symptoms, hospitalizations and general health status. The study is ongoing and will follow participants for many years.
Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to silence or knock-out individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines provides a complementary approach to those studies that aim to characterize the molecular alterations (e.g. mutations, copy number alterations) of primary tumors, such as The Cancer Genome Atlas (TCGA). The overall goal of the project is to identify cancer genetic dependencies and link them to molecular characteristics in order to prioritize targets for therapeutic development and identify the patient population that might benefit from such targets. Project Achilles data is hosted on the Cancer Dependency Map Portal (DepMap) where it has been harmonized with our genomics and cellular models data. You can access the latest and all past datasets here: https://depmap.org/portal/download/all/
BEI Resources was established by the National Institute of Allergy and Infectious Diseases (NIAID) to provide reagents, tools and information for studying Category A, B, and C priority pathogens, emerging infectious disease agents, non-pathogenic microbes and other microbiological materials of relevance to the research community. BEI Resources acquires authenticates, and produces reagents that scientists need to carry out basic research and develop improved diagnostic tests, vaccines, and therapies. By centralizing these functions within BEI Resources, access to and use of these materials in the scientific community is monitored and quality control of the reagents is assured
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DisGeNET is a discovery platform containing one of the largest publicly available collections of genes and variants associated to human diseases. DisGeNET integrates data from expert curated repositories, GWAS catalogues, animal models and the scientific literature. DisGeNET data are homogeneously annotated with controlled vocabularies and community-driven ontologies. Additionally, several original metrics are provided to assist the prioritization of genotype–phenotype relationships.
<<<!!!<<< This repository is no longer available. >>>!!!>>>The Deep Carbon Observatory (DCO) is a global community of multi-disciplinary scientists unlocking the inner secrets of Earth through investigations into life, energy, and the fundamentally unique chemistry of carbon. Deep Carbon Observatory Digital Object Registry (“DCO-VIVO”) is a centrally-managed digital object identification, object registration and metadata management service for the DCO. Digital object registration includes DCO-ID generation based on the global Handle System infrastructure and metadata collection using VIVO. Users will be able to deposit their data into the DCO Data Repository and have that data discoverable and accessible by others.
LONI’s Image and Data Archive (IDA) is a secure data archiving system. The IDA uses a robust infrastructure to provide researchers with a flexible and simple interface for de-identifying, searching, retrieving, converting, and disseminating their biomedical data. With thousands of investigators across the globe and more than 21 million data downloads to data, the IDA guarantees reliability with a fault-tolerant network comprising multiple switches, routers, and Internet connections to prevent system failure.
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The University of Northern British Columbia Dataverse is a research data repository for research data from UNBC researchers. Files are held in a secure environment on Canadian servers. The platform makes it possible for researchers to deposit data, create appropriate metadata, and version documents as they work. Researchers can choose to make content available publicly, to specific individuals, or to keep it locked.
The Seamount Catalog is a digital archive for bathymetric seamount maps from all the oceans that can be viewed and downloaded in various formats. This catalog contains morphological data, sample information, related grid and multibeam data files, as well as user-contributed files that all can be downloaded.
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As part of Halifax Regional Municipality’s commitment to improving citizen engagement and enhancing transparency and accountability to its residents, the municipality is pleased to provide public access to its data. Open Data is a permanent service provided to citizens and businesses to access data free of charge in machine readable format.
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A collection of high quality multiple sequence alignments for objective, comparative studies of alignment algorithms. The alignments are constructed based on 3D structure superposition and manually refined to ensure alignment of important functional residues. A number of subsets are defined covering many of the most important problems encountered when aligning real sets of proteins. It is specifically designed to serve as an evaluation resource to address all the problems encountered when aligning complete sequences. The first release provided sets of reference alignments dealing with the problems of high variability, unequal repartition and large N/C-terminal extensions and internal insertions. Version 2.0 of the database incorporates three new reference sets of alignments containing structural repeats, trans-membrane sequences and circular permutations to evaluate the accuracy of detection/prediction and alignment of these complex sequences. Within the resource, users can look at a list of all the alignments, download the whole database by ftp, get the "c" program to compare a test alignment with the BAliBASE reference (The source code for the program is freely available), or look at the results of a comparison study of several multiple alignment programs, using BAliBASE reference sets.
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The Geodatenkatalog.de is the metadata information system of the Geodateninfrastruktur Deutschland (GDI-DE) and forms the data basis for Geoportal.de. With the help of this central component, metadata for geodata sets, geodata services, and other IT-supported geodata applications are collected and can be researched and retrieved via Geoportal.de.
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The Universidad del Rosario Research data repository is an institutional iniciative launched in 2019 to preserve, provide access and promote the use of data resulting from Universidad del Rosario research projects. The Repository aims to consolidate an online, collaborative working space and data-sharing platform to support Universidad del Rosario researchers and their collaborators, and to ensure that research data is available to the community, in order to support further research and contribute to the democratization of knowledge. The Research data repository is the heart of an institutional strategy that seeks to ensure the generation of Findable, Accessible, Interoperable and Reusable (FAIR) data, with the aim of increasing its impact and visibility. This strategy follows the international philosophy of making research data “as open as possible and as closed as necessary”, in order to foster the expansion, valuation, acceleration and reusability of scientific research, but at the same time, safeguard the privacy of the subjects. The platform storage, preserves and facilitates the management of research data from all disciplines, generated by the researchers of all the schools and faculties of the University, that work together to ensure research with the highest standards of quality and scientific integrity, encouraging innovation for the benefit of society.
DMU Figshare is De Montfort University's institutional research data management platform. It showcases research from staff at the university.
UNC Dataverse is an open-source repository software application for archiving, sharing, and accessing research data of all kinds. Each dataverse within the larger repository contains a multitude of datasets, and each dataset contains descriptive metadata and data files. UNC Dataverse is hosted by Odum Institute for Research in Social Science.
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Our system consists of a portal (portal.geomar.de), providing access to several projects with personal password. The portal offers document exchange, common or individual blogs and fora and implementation of external webpages and -services. Moreover, you can access the expedition database, that organizes data description and exchange of cruises and expeditions for each project. Expeditions are linked to KML-files (Google-Earth compatible), allowing a visualization of all stations of a cruise/expedition. We established the linkage to the publications database /repository OceanRep (EPrints), as well as the description of model-output and linkage to paper publications.
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Etsin is a research data finder that contains descriptive information – that is, metadata – on research datasets. In the service you can search and find data from various fields of research. A researcher, research group or organisation can use Etsin to publish information on their datasets and offer them for wider use. The metadata contained in Etsin makes it easy for anyone to discover the datasets. Etsin assigns a permanent URN identifier to datasets, making it possible to link to the dataset and gather merit through its publication and use. The metadata enables users to search for datasets and evaluate the potential for reuse. Etsin includes a description of the dataset, keywords and various dataset identifiers. The dataset information includes, for example, its subject, language, author, owner and how it is licensed for reuse. Good description of data plays an important role in its discoverability and visibility. Etsin encourages comprehensive descriptions by adapting a common set of discipline independent metadata fields and by making it easy to enter metadata. Etsin only collects metadata on datasets, not the data themselves. Anyone may browse and read the metadata. Etsin can be used with a browser or through an open interface (API). The service is discipline independent and free to use. Etsin is a service provided by the Ministry of Education and Culture to actors in the Finnish research system. The service is produced by CSC – IT Center for Science (CSC). Customer service contacts and feedback is available through servicedesk@csc.fi. The service maintenance window is on the fourth Monday of every month between 4 and 6 PM (EET). During that time, the service will be out of use.
ORTOLANG is an EQUIPEX project accepted in February 2012 in the framework of investissements d’avenir. Its aim is to construct a network infrastructure including a repository of language data (corpora, lexicons, dictionaries etc.) and readily available, well-documented tools for its processing. Expected outcomes comprize: promoting research on analysis, modelling and automatic processing of our language to their highest international levels thanks to effective resource pooling; facilitating the use and transfer of resources and tools set up within public laboratories to industrial partners, notably SMEs which often cannot develop such resources and tools for language processing given the cost of investment; promoting French language and the regional languages of France by sharing expertise acquired by public laboratories. ORTOLANG is a service for the language, which is complementary to the service offered by Huma-Num (très grande infrastructure de recherche). Ortolang gives access to SLDR for speech, and CNRTL for text resources.
ALSoD is a freely available database that has been transformed from a single gene storage facility recording mutations in the SOD1 gene to a multigene ALS bioinformatics repository and analytical instrument combining genotype, phenotype, and geographical information with associated analysis tools. These include a comparison tool to evaluate genes side by side or jointly with user configurable features, a pathogenicity prediction tool using a combination of computational approaches to distinguish variants with nonfunctional characteristics from disease-associated mutations with more dangerous consequences, and a credibility tool to enable ALS researchers to objectively assess the evidence for gene causation in ALS. Furthermore, integration of external tools, systems for feedback, annotation by users, and two-way links to collaborators hosting complementary databases further enhance the functionality of ALSoD.
The COVID-19 Data Portal was launched in April 2020 to bring together relevant datasets for sharing and analysis in an effort to accelerate coronavirus research. It enables researchers to upload, access and analyse COVID-19 related reference data and specialist datasets as part of the wider European COVID-19 Data Platform.
The MRC National Survey of Health and Development 1946 (NSHD) was the first ever British birth cohort study. It has collected information from birth to the current day on the health and life circumstances of five and a half thousand men and women born during a week in March 1946 throughout England, Wales, and Scotland. The study explores differences in child development by factors like social class, biological factors, health and education. Due to the length of the study it has developed into a study of ageing.