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Found 186 result(s)

Project Achilles

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Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to silence or knock-out individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines provides a complementary approach to those studies that aim to characterize the molecular alterations (e.g. mutations, copy number alterations) of primary tumors, such as The Cancer Genome Atlas (TCGA). The overall goal of the project is to identify cancer genetic dependencies and link them to molecular characteristics in order to prioritize targets for therapeutic development and identify the patient population that might benefit from such targets. Project Achilles data is hosted on the Cancer Dependency Map Portal (DepMap) where it has been harmonized with our genomics and cellular models data. You can access the latest and all past datasets here: https://depmap.org/portal/download/all/

Genomic Data Commons

GDC

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The NCI's Genomic Data Commons (GDC) provides the cancer research community with a unified data repository that enables data sharing across cancer genomic studies in support of precision medicine. The GDC obtains validated datasets from NCI programs in which the strategies for tissue collection couples quantity with high quality. Tools are provided to guide data submissions by researchers and institutions.

IMPACT

IMPACT Cyber Trust

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The Information Marketplace for Policy and Analysis of Cyber-risk & Trust (IMPACT) program supports global cyber risk research & development by coordinating, enhancing and developing real world data, analytics and information sharing capabilities, tools, models, and methodologies. In order to accelerate solutions around cyber risk issues and infrastructure security, IMPACT makes these data sharing components broadly available as national and international resources to support the three-way partnership among cyber security researchers, technology developers and policymakers in academia, industry and the government.

OceanRep GEOMAR Repository

GEOMAR Helmholtz Centre for Ocean Research Kiel

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GEOMAR Helmholtz Centre for Ocean Research Kiel is one of the leading marine science institutions in Europe. GEOMAR investigates the chemical, physical, biological, and geological processes in the oceans, as well as their interactions with the seafloor and the atmosphere. OceanRep is an open access digital collection containing the research output of GEOMAR staff and students. Included are journal articles, conference papers, book chapters, theses and more, - with fulltext, if available. Research data are linked to the publications entries.

Virtual Fly Brain

VFB

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Virtual Fly Brain (VFB) - an interactive tool for neurobiologists to explore the detailed neuroanatomy, neuron connectivity and gene expression of the Drosophila melanogaster CNS.

Open-source Scientific Software and Service Repository

OSSR

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The ESCAPE Open-source Scientific Software and Service Repository (OSSR) is a sustainable open-access repository to share scientific software, services and datasets to the astro-particle-physics-related communities and enable open science. It is built as a curated Zenodo community (https://zenodo.org/communities/escape2020) integrated with several tools to enable a complete software life-cycle. The ESCAPE Zenodo community welcomes entries that support the software and service projects in the OSSR such as user-support documentation, tutorials, presentations and training activities. It also encourages the archival of documents and material that disseminate and support the goals of ESCAPE.

National Sleep Research Resource

NSRR

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The National Sleep Research Resource (NSRR) is an NHLBI-supported repository for sharing large amounts of sleep data (polysomnography, actigraphy and questionnaire-based) from multiple cohorts, clinical trials, and other data sources. Launched in April 2014, the mission of the NSRR is to advance sleep and circadian science by supporting secondary data analysis, algorithmic development, and signal processing through the sharing of high-quality data sets.

Staatliche Naturwissenschaftliche Sammlungen Bayerns

SNSB

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The Bavarian Natural History Collections (Staatliche Naturwissenschaftliche Sammlungen Bayerns, SNSB) are a research institution for natural history in Bavaria. They encompass five State Collections (zoology, botany, paleontology and geology, mineralogy, anthropology and paleoanatomy), the Botanical Garden Munich-Nymphenburg and eight museums with public exhibitions in Munich, Bamberg, Bayreuth, Eichstätt and Nördlingen. Our research focuses mainly on the past and present bio- and geodiversity and the evolution of animals and plants. To achieve this we have large scientific collections (almost 35,000,000 specimens), see "joint projects".

Discuss Data

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Discuss Data is an open repository for storing, sharing and discussing research data on Eastern Europe, the South Caucasus and Central Asia. The platform, launched in September 2020, is funded by the German Research Foundation (DFG) and operated by the Research Centre for East European Studies at the University of Bremen (FSO) and the Göttingen State and University Library (SUB). Discuss Data goes beyond ordinary repositories and offers an interactive online platform for the discussion and quality assessment of research data. Our aim is to create a space for academic communication and for the community-specific publication, curation, annotation and discussion of research data.

GiardiaDB

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Giardia lamblia is a significant, environmentally transmitted, human pathogen and an amitochondriate protist. It is a major contributor to the enormous worldwide burden of human diarrheal diseases, yet the basic biology of this parasite is not well understood. No virulence factor has been identified. The Giardia lamblia genome contains only 12 million base pairs distributed onto five chromosomes. Its analysis promises to provide insights about the origins of nuclear genome organization, the metabolic pathways used by parasitic protists, and the cellular biology of host interaction and avoidance of host immune systems. Since the divergence of Giardia lamblia lies close to the transition between eukaryotes and prokaryotes in universal ribosomal RNA phylogenies, it is a valuable, if not unique, model for gaining basic insights into genetic innovations that led to formation of eukaryotic cells. In evolutionary terms, the divergence of this organism is at least twice as ancient as the common ancestor for yeast and man. A detailed study of its genome will provide insights into an early evolutionary stage of eukaryotic chromosome organization as well as other aspects of the prokaryotic / eukaryotic divergence.

PSLC DataShop

Pittsburgh Science of Learning Center DataShop

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PSLC DataShop houses datasets in the areas of learning science and educational software. The site also provides online tools for analyzing and reporting the data.

DrugBank

Open Data Drug & Drug Target Database

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The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. The latest release of DrugBank (version 5.1.1, released 2018-07-03) contains 11,881 drug entries including 2,526 approved small molecule drugs, 1,184 approved biotech (protein/peptide) drugs, 129 nutraceuticals and over 5,751 experimental drugs. Additionally, 5,132 non-redundant protein (i.e. drug target/enzyme/transporter/carrier) sequences are linked to these drug entries. Each DrugCard entry contains more than 200 data fields with half of the information being devoted to drug/chemical data and the other half devoted to drug target or protein data.

Australian SuperSite Network Data Portal

SupeSites Data Portal

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<<<!!!<<< This repository is no longer available. It is part now of TERN Data Discovery Portal https://www.re3data.org/repository/r3d100012013 >>>!!!>>>

International Earth Rotation and Reference Systems Service

IERS

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The IERS provides data on Earth orientation, on the International Celestial Reference System/Frame, on the International Terrestrial Reference System/Frame, and on geophysical fluids. It maintains also Conventions containing models, constants and standards.

VectorBase

Bioinformatics Resource for Invertebrate Vectors of Human Pathogens

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VectorBase provides data on arthropod vectors of human pathogens. Sequence data, gene expression data, images, population data, and insecticide resistance data for arthropod vectors are available for download. VectorBase also offers genome browser, gene expression and microarray repository, and BLAST searches for all VectorBase genomes. VectorBase Genomes include Aedes aegypti, Anopheles gambiae, Culex quinquefasciatus, Ixodes scapularis, Pediculus humanus, Rhodnius prolixus. VectorBase is one the Bioinformatics Resource Centers (BRC) projects which is funded by National Institute of Allergy and Infectious Diseases (NAID).

Henry A. Murray Research Archive at IQSS, Harvard University

Murray Archive

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The Henry A. Murray Research Archive is Harvard's endowed, permanent repository for quantitative and qualitative research data at the Institute for Quantitative Social Science, and provides physical storage for the entire IQSS Dataverse Network. Our collection comprises over 100 terabytes of data, audio, and video. We preserve in perpetuity all types of data of interest to the research community, including numerical, video, audio, interview notes, and other data. We accept data deposits through this web site, which is powered by our Dataverse Network software

MG-RAST

Metagenomics analysis server

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The MG-RAST server is an open source system for annotation and comparative analysis of metagenomes. Users can upload raw sequence data in fasta format; the sequences will be normalized and processed and summaries automatically generated. The server provides several methods to access the different data types, including phylogenetic and metabolic reconstructions, and the ability to compare the metabolism and annotations of one or more metagenomes and genomes. In addition, the server offers a comprehensive search capability. Access to the data is password protected, and all data generated by the automated pipeline is available for download in a variety of common formats. MG-RAST has become an unofficial repository for metagenomic data, providing a means to make your data public so that it is available for download and viewing of the analysis without registration, as well as a static link that you can use in publications. It also requires that you include experimental metadata about your sample when it is made public to increase the usefulness to the community.

NCBI Genome

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<<<!!!<<< Effective May 2024, NCBI's Genome resource will no longer be available. NCBI Genome data can now be found on the NCBI Datasets taxonomy pages. https://www.re3data.org/repository/r3d100014298 >>>!!!>>> The Genome database contains annotations and analysis of eukaryotic and prokaryotic genomes, as well as tools that allow users to compare genomes and gene sequences from humans, microbes, plants, viruses and organelles. Users can browse by organism, and view genome maps and protein clusters.

NCBI dbMHC

Major histocompatibility Complex database

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<<<!!!<<< The repository is no longer available - Data previously on the site are now available at ftp://ftp.ncbi.nlm.nih.gov/pub/mhc/mhc/Final Archive. >>>!!!>>> The dbMHC database provides an open, publicly accessible platform for DNA and clinical data related to the human Major Histocompatibility Complex (MHC). The dbMHC provides access to human leukocyte antigen (HLA) sequences, HLA allele and haplotype frequencies, and clinical datasets.

eBird

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eBird is among the world’s largest biodiversity-related science projects, with more than 1 billion records, more than 100 million bird sightings contributed annually by eBirders around the world, and an average participation growth rate of approximately 20% year over year. A collaborative enterprise with hundreds of partner organizations, thousands of regional experts, and hundreds of thousands of users, eBird is managed by the Cornell Lab of Ornithology. eBird data document bird distribution, abundance, habitat use, and trends through checklist data collected within a simple, scientific framework. Birders enter when, where, and how they went birding, and then fill out a checklist of all the birds seen and heard during the outing. Data can be accessed from the Science tab on the website.

NCBI dbGaP

DataBase of Genotypes And Phenotypes

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The NCBI database of Genotypes and Phenotypes archives and distributes the results of studies that have investigated the interaction of genotype and phenotype, including genome-wide association studies, medical sequencing, molecular diagnostic assays, and association between genotype and non-clinical traits. The database provides summaries of studies, the contents of measured variables, and original study document text. dbGaP provides two types of access for users, open and controlled. Through the controlled access, users may access individual-level data such as phenotypic data tables and genotypes.

HSRC Research Data Service

Human Sciences Research Council Research Data Service

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The HSRC Research Data Service provides a digital repository facility for the HSRC's research data in support of evidence based human and social development in South Africa and the broader region. It includes both quantitative and qualitative data. Access to data is dependent on ethical requirements for protecting research participants, as well as on legal agreements with the owners, funders or in the case of data owned by the HSRC, the requirements of the depositors of the data.

World Data Center for Oceanography, Obninsk

WDC - Oceanography, Obninsk

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World Data Center for Oceanography serves to store and provide to users data on physical, chemical and dynamical parameters of the global ocean as well as oceanography-related papers and publications, which are either came from other countries through the international exchange or provided to the international exchange by organizations of the Russian Federation

Space Physics Data Facility

NASA's Space Physics Data Facility

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The Space Physics Data Facility (SPDF) leads in the design and implementation of unique multi-mission and multi-disciplinary data services and software to strategically advance NASA's solar-terrestrial program, to extend our science understanding of the structure, physics and dynamics of the Heliosphere of our Sun and to support the science missions of NASA's Heliophysics Great Observatory. Major SPDF efforts include multi-mission data services such as Heliophysics Data Portal (formerly VSPO), CDAWeb and CDAWeb Inside IDL,and OMNIWeb Plus (including COHOWeb, ATMOWeb, HelioWeb and CGM) , science planning and orbit services such as SSCWeb, data tools such as the CDF software and tools, and a range of other science and technology research efforts. The staff supporting SPDF includes scientists and information technology experts.

ELRA Catalogue of Language Resources

ELRA Catalogue

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An increasing number of Language Resources (LT) in the various fields of Human Language Technology (HLT) are distributed on behalf of ELRA via its operational body ELDA, thanks to the contribution of various players of the HLT community. Our aim is to provide Language Resources, by means of this repository, so as to prevent researchers and developers from investing efforts to rebuild resources which already exist as well as help them identify and access those resources.