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HISTAT (Historical Statistics)provides data from studies of population, economic and social history as well as the historical Statistics under a single user interface to be made available online. HISTAT offers a variety of time series, Historical Statistics primarily from Germany, partly down to the 16 . century; the database is structured theme-and study-oriented. Studies are listed by subject area and can be individually selected. using an alphabetical list of authors of individual studies can also be selected. Moreover, a study on cross Keyword is offered. HISTAT provides information and research opportunities to both study level as well as at time series level. It offered a thesaurus-based meta-search for words, authors and studies in the study descriptions, the data (time series definitions) and the sources.
The Virtual Research Environment (VRE) is an open-source data management platform that enables medical researchers to store, process and share data in compliance with the European Union (EU) General Data Protection Regulation (GDPR). The VRE addresses the present lack of digital research data infrastructures fulfilling the need for (a) data protection for sensitive data, (b) capability to process complex data such as radiologic imaging, (c) flexibility for creating own processing workflows, (d) access to high performance computing. The platform promotes FAIR data principles and reduces barriers to biomedical research and innovation. The VRE offers a web portal with graphical and command-line interfaces, segregated data zones and organizational measures for lawful data onboarding, isolated computing environments where large teams can collaboratively process sensitive data privately, analytics workbench tools for processing, analyzing, and visualizing large datasets, automated ingestion of hospital data sources, project-specific data warehouses for structured storage and retrieval, graph databases to capture and query ontology-based metadata, provenance tracking, version control, and support for automated data extraction and indexing. The VRE is based on a modular and extendable state-of-the art cloud computing framework, a RESTful API, open developer meetings, hackathons, and comprehensive documentation for users, developers, and administrators. The VRE with its concerted technical and organizational measures can be adopted by other research communities and thus facilitates the development of a co-evolving interoperable platform ecosystem with an active research community.