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Found 178 result(s)

ALSoD

ALS Online Database

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ALSoD is a freely available database that has been transformed from a single gene storage facility recording mutations in the SOD1 gene to a multigene ALS bioinformatics repository and analytical instrument combining genotype, phenotype, and geographical information with associated analysis tools. These include a comparison tool to evaluate genes side by side or jointly with user configurable features, a pathogenicity prediction tool using a combination of computational approaches to distinguish variants with nonfunctional characteristics from disease-associated mutations with more dangerous consequences, and a credibility tool to enable ALS researchers to objectively assess the evidence for gene causation in ALS. Furthermore, integration of external tools, systems for feedback, annotation by users, and two-way links to collaborators hosting complementary databases further enhance the functionality of ALSoD.

Screening Unit Berlin-Buch

Screening Unit Jens Peter von Kries

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The mission of the platform is to enable access for academic projects towards experiments in high-throughput without loss of IP and on a cost basis, which does not restrict access towards HTS usage. The FMP hosts the central open access technology platform of EU-OPENSCREEN, the ChemBioNet and theHelmholtz-Initiative für Wirkstoffforschung, the Screening Unit. The Unit serves for systematic screening of large compound or genome-wide RNAi libraries with state-of-the-art equipment like automated microscopes and microfluidic systems. The Screening Unit is part of the Chemical Biology Platform of the FMP also supported by the MDC. See also: https://www.mdc-berlin.de/screening-unit

Phonogrammarchiv

PhA

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The Phonogrammarchiv is a multi-disciplinary research sound and video archive, covering holdings from all continents. Since its foundation in 1899 the Phonogrammarchiv has been building up its holdings by cooperating with Austrian scholars and archiving their collected material, or by fieldwork conducted by staff members on special topics exploring new fields of methods and contents. The main tasks comprise the production, annotation, cataloguing and long-term preservation of audio-visual field recordings, making the cultural heritage available for future generations and enabling the dissemination of the recordings as well as technical developments in the field of AV recording and storage. Thus the Phonogrammarchiv adds to infrastructural performance valuable to both the scholarly community and the public at large.