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Found 9 result(s)
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<<<!!!<<< This repository is no longer available. >>>!!!>>> C3-Grid is an ALREADY FINISHED project within D-Grid, the initiative to promote a grid-based e-Science framework in Germany. The goal of C3-Grid is to support the workflow of Earth system researchers. A grid infrastructure will be implemented that allows efficient distributed data processing and inter-institutional data exchange. Aim of the effort was to develop an infrastructure for uniform access to heterogeneous data and distributed data processing. The work was structured in two projects funded by the Federal Ministry of Education and Research. The first project was part of the D-Grid initiative and explored the potential of grid technology for climate research and developed a prototype infrastructure. Details about the C3Grid architecture are described in “Earth System Modelling – Volume 6”. In the second phase "C3Grid - INAD: Towards an Infrastructure for General Access to Climate Data" this infrastructure was improved especially with respect to interoperability to Earth System Grid Federation (ESGF). Further the portfolio of available diagnostic workflows was expanded. These workflows can be re-used now in adjacent infrastructures MiKlip Evaluation Tool (http://www.fona-miklip.de/en/index.php) and as Web Processes within the Birdhouse Framework (http://bird-house.github.io/). The Birdhouse Framework is now funded as part of the European Copernicus Climate Change Service (https://climate.copernicus.eu/) managed by ECMWF and will be extended to provide scalable processing services for ESGF hosted data at DKRZ as well as IPSL and BADC.
Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to silence or knock-out individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines provides a complementary approach to those studies that aim to characterize the molecular alterations (e.g. mutations, copy number alterations) of primary tumors, such as The Cancer Genome Atlas (TCGA). The overall goal of the project is to identify cancer genetic dependencies and link them to molecular characteristics in order to prioritize targets for therapeutic development and identify the patient population that might benefit from such targets. Project Achilles data is hosted on the Cancer Dependency Map Portal (DepMap) where it has been harmonized with our genomics and cellular models data. You can access the latest and all past datasets here: https://depmap.org/portal/download/all/
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<<<!!!<<< There are no more data available. >>>!!!>>> HalOcAt brings together global oceanic and atmospheric data of mainly short-lived brominated and iodinated trace gases.
MEMENTO aims to become a valuable tool for identifying regions of the world ocean that should be targeted in future work to improve the quality of air-sea flux estimates.
INDI was formed as a next generation FCP effort. INDI aims to provide a model for the broader imaging community while simultaneously creating a public dataset capable of dwarfing those that most groups could obtain individually.
The Cancer Cell Line Encyclopedia project is a collaboration between the Broad Institute, and the Novartis Institutes for Biomedical Research and its Genomics Institute of the Novartis Research Foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models, to develop integrated computational analyses that link distinct pharmacologic vulnerabilities to genomic patterns and to translate cell line integrative genomics into cancer patient stratification. The CCLE provides public access to genomic data, analysis and visualization for about 1000 cell lines.
BeiDare2 is currently at beta version. All new users should try the new service as we no longer provide training for the classic BioDare. - BioDare stands for Biological Data Repository, its main focus is data from circadian experiments. BioDare is an online facility to share, store, analyse and disseminate timeseries data, focussing on circadian clock data, with browser and web service interfaces. Toolbox features include an improved, speedier FFT-NLLs routine and ROBuST’s Spectrum Resampling tool that will analyse rhythmic time series data.