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Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to silence or knock-out individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines provides a complementary approach to those studies that aim to characterize the molecular alterations (e.g. mutations, copy number alterations) of primary tumors, such as The Cancer Genome Atlas (TCGA). The overall goal of the project is to identify cancer genetic dependencies and link them to molecular characteristics in order to prioritize targets for therapeutic development and identify the patient population that might benefit from such targets. Project Achilles data is hosted on the Cancer Dependency Map Portal (DepMap) where it has been harmonized with our genomics and cellular models data. You can access the latest and all past datasets here: https://depmap.org/portal/download/all/
<<<!!!<<< This repository is no longer available. >>>!!!>>> BioVeL is a virtual e-laboratory that supports research on biodiversity issues using large amounts of data from cross-disciplinary sources. BioVeL supports the development and use of workflows to process data. It offers the possibility to either use already made workflows or create own. BioVeL workflows are stored in MyExperiment - Biovel Group http://www.myexperiment.org/groups/643/content. They are underpinned by a range of analytical and data processing functions (generally provided as Web Services or R scripts) to support common biodiversity analysis tasks. You can find the Web Services catalogued in the BiodiversityCatalogue.
The European Union Open Data Portal is the single point of access to a growing range of data from the institutions and other bodies of the European Union (EU). Data are free for you to use and reuse for commercial or non-commercial purposes. By providing easy and free access to data, the portal aims to promote their innovative use and unleash their economic potential. It also aims to help foster the transparency and the accountability of the institutions and other bodies of the EU. The EU Open Data Portal is managed by the Publications Office of the European Union. Implementation of the EU's open data policy is the responsibility of the Directorate-General for Communications Networks, Content and Technology of the European Commission.
Argo is an international programme using autonomous floats to collect temperature, salinity and current data in the ice-free oceans. It is teamed with the Jason ocean satellite series. Argo will soon reach its target of 3000 floats delivering data within 24 hours to researchers and operational centres worldwide. 23 countries contribute floats to Argo and many others help with float deployments. Argo has revolutionized the collection of information from inside the oceans. ARGO Project is organized in regional and national Centers with a Project Office, an Information Center (AIC) and 2 Global Data Centers (GDAC), at the United States and at France. Each DAC submits regularly all its new files to both USGODAE and Coriolis GDACs.The whole Argo data set is available in real time and delayed mode from the global data centres (GDACs). The internet addresses are: https://nrlgodae1.nrlmry.navy.mil/ and http://www.argodatamgt.org
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The Marine Data Archive (MDA) is an online repository specifically developed to independently archive data files in a fully documented manner. The MDA can serve individuals, consortia, working groups and institutes to manage data files and file versions for a specific context (project, report, analysis, monitoring campaign), as a personal or institutional archive or back-up system and as an open repository for data publication.