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Giardia lamblia is a significant, environmentally transmitted, human pathogen and an amitochondriate protist. It is a major contributor to the enormous worldwide burden of human diarrheal diseases, yet the basic biology of this parasite is not well understood. No virulence factor has been identified. The Giardia lamblia genome contains only 12 million base pairs distributed onto five chromosomes. Its analysis promises to provide insights about the origins of nuclear genome organization, the metabolic pathways used by parasitic protists, and the cellular biology of host interaction and avoidance of host immune systems. Since the divergence of Giardia lamblia lies close to the transition between eukaryotes and prokaryotes in universal ribosomal RNA phylogenies, it is a valuable, if not unique, model for gaining basic insights into genetic innovations that led to formation of eukaryotic cells. In evolutionary terms, the divergence of this organism is at least twice as ancient as the common ancestor for yeast and man. A detailed study of its genome will provide insights into an early evolutionary stage of eukaryotic chromosome organization as well as other aspects of the prokaryotic / eukaryotic divergence.
High spatial resolution, contemporary data on human population distributions are a prerequisite for the accurate measurement of the impacts of population growth, for monitoring changes and for planning interventions. The WorldPop project aims to meet these needs through the provision of detailed and open access population distribution datasets built using transparent approaches. The WorldPop project was initiated in October 2013 to combine the AfriPop, AsiaPop and AmeriPop population mapping projects. It aims to provide an open access archive of spatial demographic datasets for Central and South America, Africa and Asia to support development, disaster response and health applications. The methods used are designed with full open access and operational application in mind, using transparent, fully documented and peer-reviewed methods to produce easily updatable maps with accompanying metadata and measures of uncertainty.
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The Coriolis Data Centre handles operational oceanography measurements made in situ, complementing the measurement of the ocean surface made using instruments aboard satellites. This work is realised through the establishment of permanent networks with data collected by ships or autonomous systems that are either fixed or drifting. This data can be used to construct a snapshot of water mass structure and current intensity.