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Found 3 result(s)

NetPath

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<<<!!!<<< This repository is no longer available. >>>!!!>>> NetPath is currently one of the largest open-source repository of human signaling pathways that is all set to become a community standard to meet the challenges in functional genomics and systems biology. Signaling networks are the key to deciphering many of the complex networks that govern the machinery inside the cell. Several signaling molecules play an important role in disease processes that are a direct result of their altered functioning and are now recognized as potential therapeutic targets. Understanding how to restore the proper functioning of these pathways that have become deregulated in disease, is needed for accelerating biomedical research. This resource is aimed at demystifying the biological pathways and highlights the key relationships and connections between them. Apart from this, pathways provide a way of reducing the dimensionality of high throughput data, by grouping thousands of genes, proteins and metabolites at functional level into just several hundreds of pathways for an experiment. Identifying the active pathways that differ between two conditions can have more explanatory power than just a simple list of differentially expressed genes and proteins.

LIAS

A Global Information System for Lichenized and Non-Lichenized Ascomycetes

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LIAS is a global information system for Lichenized and Non-Lichenized Ascomycetes. It includes several interoperable data repositories. In recent years, the two core components ‘LIAS names’ and ‘LIAS light’ have been much enlarged. LIAS light is storing phenotypic trait data. They includes > 10,700 descriptions (about 2/3 of all known lichen species), each with up to 75 descriptors comprising 2,000 traits (descriptor states and values), including 800 secondary metabolites. 500 traits may have biological functions and more than 1,000 may have phylogenetic relevance. LIAS is thus one of the most comprehensive trait databases in organismal biology. The online interactive identification key for more than 10,700 lichens is powered by the Java applet NaviKey and has been translated into 19 languages (besides English) in cooperation with lichenologists worldwide. The component ‘LIAS names’ is a platform for managing taxonomic names and classifications with currently >50,000 names, including the c. 12,000 accepted species and recognized synonyms. The LIAS portal contents, interfaces, and databases run on servers of the IT Center of the Bavarian Natural History Collections and are maintained there. 'LIAS names' and ‘LIAS light’ also deliver content data to the Catalogue of Life, acting as the Global Species Database (GSD) for lichens. LIAS gtm is a database for visualising the geographic distribution of lichen traits. LIAS is powered by the Diversity Workbench database framework with several interfaces for data management and publication. The LIAS long-term project was initiated in the early 1990s and has since been continued with funding from the DFG, the BMBF, and the EU.

UniMES

UniProt Metagenomic and Environmental Sequences

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<<<!!!<<< Retirement of UniProt Metagenomic and Environmental Sequences (UniMES): UniProt has retired UniMES as there is now a resource at the EBI that is dedicated to serving metagenomic researchers. Henceforth, we recommend using the EBI Metagenomics portal instead https://www.ebi.ac.uk/metagenomics/ . In addition to providing a repository of metagenomics sequence data, EBI Metagenomics allows you to view functional and taxonomic analyses and to submit your own samples for analysis. >>>!!!>>> The UniProt Metagenomic and Environmental Sequences (UniMES) database is a repository specifically developed for metagenomic and environmental data. We provide UniMES clusters in order to obtain complete coverage of sequence space at different resolutions.