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Found 994 result(s)
BindingDB is a public, web-accessible knowledgebase of measured binding affinities, focusing chiefly on the interactions of proteins considered to be candidate drug-targets with ligands that are small, drug-like molecules. BindingDB supports medicinal chemistry and drug discovery via literature awareness and development of structure-activity relations (SAR and QSAR); validation of computational chemistry and molecular modeling approaches such as docking, scoring and free energy methods; chemical biology and chemical genomics; and basic studies of the physical chemistry of molecular recognition. BindingDB also includes a small collection of host-guest binding data of interest to chemists studying supramolecular systems. The data collection derives from a variety of measurement techniques, including enzyme inhibition and kinetics, isothermal titration calorimetry, NMR, and radioligand and competition assays. BindingDB includes data extracted from the literature and from US Patents by the BindingDB project, selected PubChem confirmatory BioAssays, and ChEMBL entries for which a well defined protein target ("TARGET_TYPE='PROTEIN'") is provided.
The BioCyc database collection of Pathway/Genome Databases (PGDBs) provides a reference on the genomes and metabolic pathways of thousands of sequenced organisms. BioCyc PGDBs are generated by software that predict the metabolic pathways of completely sequenced organisms, predict which genes code for missing enzymes in metabolic pathways, and predict operons. BioCyc also integrates information from other bioinformatics databases, such as protein feature and Gene Ontology information from UniProt. The BioCyc website provides a suite of software tools for database searching and visualization, for omics data analysis, and for comparative genomics and comparative pathway questions. From 2016 on, access to the EcoCyc and MetaCyc databases will remain free. Subscriptions to the other 7,600 BioCyc databases will be available to institutions (e.g., libraries), and to individuals. Access to licensed databases via: https://biocyc.org/Product-summary.shtml.
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The Repositorio de Datos de Investigación del Consejo Nacional de Investigaciones Científicas y Técnicas is a plataform of open access centralized in the storage, preservation and difusion of research data, which facilitates the access and reutilization of the scientific information created and self-archived by organism's researchers, fellowships and support staff.
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Androgen Receptor Gene Mutations Database is for all who are interested in mutations of the Androgen Receptor Gene. In light of the difficulty in getting new AR mutations published the curator will now accept new mutations that have not been published, provided that it is from a reputable research or clinical laboratory. The curator also strongly suggests that where possible, particularly in the case of new unique mutations that an attempt be made to at least confirm the pathogenicity of the putatative mutation, by showing that the mutation when transfected into a suitable expression system produces a mutant androgen receptor protein.
ViralZone is a SIB Swiss Institute of Bioinformatics web-resource for all viral genus and families, providing general molecular and epidemiological information, along with virion and genome figures. Each virus or family page gives an easy access to UniProtKB/Swiss-Prot viral protein entries.
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The nature of the ‘Bridge of Data’ project is to design and build a platform that allows collecting, searching, analyzing and sharing open research data and to provide it with unique data collected from the three most important Pomeranian universities: Gdańsk University of Technology, Medical University of Gdańsk and the University of Gdańsk. These data will be made available free of charge to the scientific community, entrepreneurs and the public. A bridge will be built to allow reuse of Open Research Data. The available research data will be described by standards developed by dedicated, experienced scientific teams. The metadata will allow other external computer systems to interpret the collected data. ORD descriptions will also include data reuse or reduction scenarios to facilitate further processing.
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The mission of the platform is to enable access for academic projects towards experiments in high-throughput without loss of IP and on a cost basis, which does not restrict access towards HTS usage. The FMP hosts the central open access technology platform of EU-OPENSCREEN, the ChemBioNet and theHelmholtz-Initiative für Wirkstoffforschung, the Screening Unit. The Unit serves for systematic screening of large compound or genome-wide RNAi libraries with state-of-the-art equipment like automated microscopes and microfluidic systems. The Screening Unit is part of the Chemical Biology Platform of the FMP also supported by the MDC. See also: https://www.mdc-berlin.de/screening-unit
The PRIDE PRoteomics IDEntifications database is a centralized, standards compliant, public data repository for proteomics data, including protein and peptide identifications, post-translational modifications and supporting spectral evidence. PRIDE encourages and welcomes direct user submissions of mass spectrometry data to be published in peer-reviewed publications.
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The Finnish Social Science Data Archive (FSD) is a national resource centre for research and education. FSD's mission is to preserve data collected to study Finnish society, people and cultural phenomena in the long term. FSD archives, promotes and disseminates digital research data for research, teaching and learning purposes. Data descriptions are published in Finnish and English on FSD’s service portal Aila, through which users also download data. Quantitative datasets are translated from Finnish into English on request, and a large number of datasets are available in English. All services are free of charge. FSD promotes transparency, accumulation and efficient reuse of scientific research as well as open access to research data. FSD is the Finnish Service Provider for CESSDA ERIC.
Fishbase is a global species database and encyclopedia of over 30,000 species and subspecies of fishes that is searchable by common name, genus, species, geography, family, ecosystem, references literature, tools, etc. Links to other, related databases such as the Catalog of Fishes, GenBack, and LarvalBase. Associated with a partner journal, Acta Ichthyologica et Piscatoria. With mirror sites in English, German, French Spanish, Portuguese, French, Swedish, Chinese and Arabian language.
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The Jülich Observatory for Cloud Evolution (JOYCE) operates ground-based active and passive remote sensing instruments for cloud and precipitation observations. ​JOYCE is based on a long-term successful collaboration between the University of Cologne, the University of Bonn and the Research Centre Jülich. Since 2017 JOYCE is transformed into a Core Facility (JOYCE - CF) funded by the DFG (Deutsche Forschungsgemeinschaft) with the aim of high quality radar and passive microwave observations of the atmosphere. JOYCE will serve as a reference center for best practices in data acquisition, storage and distribution. JOYCE instrumentation aims to observe spatial and temporal variability of atmospheric water cycle variables.
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ISDC's online service portal is an access point for all manner of geoscientific geodata, its corresponding metadata, scientific documentation and software tools. The majority of the data and information, the portal currently offers to the public, are global geomonitoring products such as satellite orbit and Earth gravity field data as well as geomagnetic and atmospheric data for the exploration. These products for Earths changing system are provided via state-of-the art retrieval techniques. The projects hosted are: CHAMP, GGP, GRACE, GNSS, GGSP, GGOS, GPS-PDR, ICGEM, TerraSAR-x (TSX-TOR) and TanDEM-X.
<<<!!!<<< Duplicate to https://www.re3data.org/repository/r3d100011116 , this entry is no longer maintained >>>!!!>>> GGOS is the Global Geodetic Observing System of the International Association of Geodesy (IAG). It provides observations of the three fundamental geodetic observables and their variations, that is, the Earth's shape, the Earth's gravity field and the Earth's rotational motion. GGOS integrates different geodetic techniques, different models, different approaches in order to ensure a long-term, precise monitoring of the geodetic observables in agreement with the Integrated Global Observing Strategy (IGOS). GGOS provides the observational basis to maintain a stable, accurate and global reference frame and in this function is crucial for all Earth observation and many practical applications.
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Applying the Terrestrial Systems Modeling Platform, TerrSysMP, this dataset consists of the first simulated long-term (1989-2018), high-resolution (~12.5km) terrestrial system climatology over Europe, which comprises variables from groundwater across the land surface to the top of atmosphere (G2A). This data set constitutes a near-natural realization of the European terrestrial system, which cannot be obtained from observations, and can, thus, serve as a reference for global change simulations including human water use and climate change.
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<<<!!!<<< This repository is no longer available. >>>!!!>>> This page is not longer active, please use www.marine-data.de instead. Our data portal data.awi.de offers an integrative one-stop shop framework for discovering AWI research platforms including devices and sensors, tracklines, field reports, peer-reviewed publications, GIS products and mostly important data and data products archived in PANGAEA.
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<<<!!!<< With the implementation of GlyTouCan (https://glytoucan.org/) the mission of GlycomeDB comes to an end. >>>!!!>>> With the new database, GlycomeDB, it is possible to get an overview of all carbohydrate structures in the different databases and to crosslink common structures in the different databases. Scientists are now able to search for a particular structure in the meta database and get information about the occurrence of this structure in the five carbohydrate structure databases.