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Found 1821 result(s)
STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations; they are derived from four sources: - Genomic Context - High-throughput Experiments - (Conserved) Coexpression - Previous Knowledge STRING quantitatively integrates interaction data from these sources for a large number of organisms, and transfers information between these organisms where applicable.
Using serial analysis of gene expression (SAGE) and microarrays, we are examining total mRNA populations in all developmental stages, both in whole worms and in specific cells and tissues. In addition, we are building promoter::GFP constructs to monitor gene expression in transgenic worms, focusing on C. elegans genes that have human orthologues. Also available are web-based PCR primer design tools, and access to information about our C. elegans Fosmid library.
BRENDA is the main collection of enzyme functional data available to the scientific community worldwide. The enzymes are classified according to the Enzyme Commission list of enzymes. It is available free of charge for via the internet ( and as an in-house database for commercial users (requests to our distributor Biobase). The enzymes are classified according to the Enzyme Commission list of enzymes. Some 5000 "different" enzymes are covered. Frequently enzymes with very different properties are included under the same EC number. BRENDA includes biochemical and molecular information on classification, nomenclature, reaction, specificity, functional parameters, occurrence, enzyme structure, application, engineering, stability, disease, isolation, and preparation. The database also provides additional information on ligands, which function as natural or in vitro substrates/products, inhibitors, activating compounds, cofactors, bound metals, and other attributes.
CBS offers Comprehensive public databases of DNA- and protein sequences, macromolecular structure, g ene and protein expression levels, pathway organization and cell signalling, have been established to optimise scientific exploitation of the explosion of data within biology. Unlike many other groups in the field of biomolecular informatics, Center for Biological Sequence Analysis directs its research primarily towards topics related to the elucidation of the functional aspects of complex biological mechanisms. Among contemporary bioinformatics concerns are reliable computational interpretation of a wide range of experimental data, and the detailed understanding of the molecular apparatus behind cellular mechanisms of sequence information. By exploiting available experimental data and evidence in the design of algorithms, sequence correlations and other features of biological significance can be inferred. In addition to the computational research the center also has experimental efforts in gene expression analysis using DNA chips and data generation in relation to the physical and structural properties of DNA. In the last decade, the Center for Biological Sequence Analysis has produced a large number of computational methods, which are offered to others via WWW servers.
The National Pollutant Release Inventory (NPRI) is Canada's legislated, publicly accessible inventory of pollutant releases (to air, water and land), disposals and transfers for recycling. It is a key resource for: identifying pollution prevention priorities; supporting the assessment and risk management of chemicals, and air quality modelling; helping develop targeted regulations for reducing releases of toxic substances and air pollutants; encouraging actions to reduce the release of pollutants into the environment; and improving public understanding. The NPRI comprises: Information reported by facilities and published by Environment and Climate Change Canada under the authority of Sections 46 – 50 of the Canadian Environmental Protection Act, 1999 (CEPA 1999); and Comprehensive emission summaries and trends for key air pollutants, based on facility-reported data and emission estimates for other sources such as motor vehicles, residential heating, forest fires and agriculture. For the latest reporting year, 7,708 facilities reported to the NPRI on more than 300 listed substances. Comprehensive air pollutant emission summaries and trends were compiled by Environment and Climate Change Canada for criteria air contaminants (the main pollutants contributing to smog, acid rain and/or poor air quality), selected heavy metals and persistent organic pollutants.
The World Data Centre section provides software and data catalogue information and data produced by IPS Radio and Space Services over the past few past decades. You can download data files, plot graphs from data files, check data availability, retrieve data sets and station information.
The National Deep Submergence Facility (NDSF) operates the Human Occupied Vehicle (HOV) Alvin, the Remote Operated Vehicle (ROV) Jason 2, and the Autonomous Underwater Vehicle (AUV) Sentry. Data acquired with these platforms is provided both to the science party on each expedition, and to the Woods Hole Oceanographic Institution (WHOI) Data Library.
dbEST is a division of GenBank that contains sequence data and other information on "single-pass" cDNA sequences, or "Expressed Sequence Tags", from a number of organisms. Expressed Sequence Tags (ESTs) are short (usually about 300-500 bp), single-pass sequence reads from mRNA (cDNA). Typically they are produced in large batches. They represent a snapshot of genes expressed in a given tissue and/or at a given developmental stage. They are tags (some coding, others not) of expression for a given cDNA library. Most EST projects develop large numbers of sequences. These are commonly submitted to GenBank and dbEST as batches of dozens to thousands of entries, with a great deal of redundancy in the citation, submitter and library information. To improve the efficiency of the submission process for this type of data, we have designed a special streamlined submission process and data format. dbEST also includes sequences that are longer than the traditional ESTs, or are produced as single sequences or in small batches. Among these sequences are products of differential display experiments and RACE experiments. The thing that these sequences have in common with traditional ESTs, regardless of length, quality, or quantity, is that there is little information that can be annotated in the record. If a sequence is later characterized and annotated with biological features such as a coding region, 5'UTR, or 3'UTR, it should be submitted through the regular GenBank submissions procedure (via BankIt or Sequin), even if part of the sequence is already in dbEST. dbEST is reserved for single-pass reads. Assembled sequences should not be submitted to dbEST. GenBank will accept assembled EST submissions for the forthcoming TSA (Transcriptome Shotgun Assembly) division. The individual reads which make up the assembly should be submitted to dbEST, the Trace archive or the Short Read Archive (SRA) prior to the submission of the assemblies.
The Gene database provides detailed information for known and predicted genes defined by nucleotide sequence or map position. Gene supplies gene-specific connections in the nexus of map, sequence, expression, structure, function, citation, and homology data. Unique identifiers are assigned to genes with defining sequences, genes with known map positions, and genes inferred from phenotypic information. These gene identifiers are used throughout NCBI's databases and tracked through updates of annotation. Gene includes genomes represented by NCBI Reference Sequences (or RefSeqs) and is integrated for indexing and query and retrieval from NCBI's Entrez and E-Utilities systems.
The IMEx consortium is an international collaboration between a group of major public interaction data providers who have agreed to share curation effort and develop and work to a single set of curation rules when capturing data from both directly deposited interaction data or from publications in peer-reviewed journals, capture full details of an interaction in a “deep” curation model, perform a complete curation of all protein-protein interactions experimentally demonstrated within a publication, make these interaction available in a single search interface on a common website, provide the data in standards compliant download formats, make all IMEx records freely accessible under the Creative Commons Attribution License
IntAct provides a freely available, open source database system and analysis tools for molecular interaction data. All interactions are derived from literature curation or direct user submissions and are freely available.
UniProtKB/Swiss-Prot is the manually annotated and reviewed section of the UniProt Knowledgebase (UniProtKB). It is a high quality annotated and non-redundant protein sequence database, which brings together experimental results, computed features and scientific conclusions. Since 2002, it is maintained by the UniProt consortium and is accessible via the UniProt website.
The Khazar University Institutional Repository (KUIR), a suite of services offered by the Library Information Center, is an institutional repository maintained to support the university's researchers, collaborators, and students. Repository content consists of collections of research materials in digital format produced and selected by Khazar University faculty and their collaborators.
WFCC Global Catalogue of Microorganisms (GCM) is expected to be a robust, reliable and user-friendly system to help culture collections to manage, disseminate and share the information related to their holdings. It also provides a uniform interface for the scientific and industrial communities to access the comprehensive microbial resource information.
ScholarSphere is a secure repository service enabling the Penn State community to share its research and scholarly work with a worldwide audience. Faculty, staff, and students can use ScholarSphere to collect their work in one location and create a durable and citeable record of their papers, presentations, publications, data sets, or other scholarly creations. Through this service, Penn State researchers can also comply with grant-funding-agency requirements for sharing and managing research data.
VegBank is the vegetation plot database of the Ecological Society of America's Panel on Vegetation Classification. VegBank consists of three linked databases that contain the actual plot records, vegetation types recognized in the U.S. National Vegetation Classification and other vegetation types submitted by users, and all plant taxa recognized by ITIS/USDA as well as all other plant taxa recorded in plot records. Vegetation records, community types and plant taxa may be submitted to VegBank and may be subsequently searched, viewed, annotated, revised, interpreted, downloaded, and cited. VegBank receives its data from the VegBank community of users.
The World Atlas of Language Structures (WALS) is a large database of structural (phonological, grammatical, lexical) properties of languages gathered from descriptive materials (such as reference grammars) by a team of 55 authors (many of them the leading authorities on the subject).
The Space Physics Data Facility (SPDF) leads in the design and implementation of unique multi-mission and multi-disciplinary data services and software to strategically advance NASA's solar-terrestrial program, to extend our science understanding of the structure, physics and dynamics of the Heliosphere of our Sun and to support the science missions of NASA's Heliophysics Great Observatory. Major SPDF efforts include multi-mission data services such as Heliophysics Data Portal (formerly VSPO), CDAWeb and CDAWeb Inside IDL,and OMNIWeb Plus (including COHOWeb, ATMOWeb, HelioWeb and CGM) , science planning and orbit services such as SSCWeb, data tools such as the CDF software and tools, and a range of other science and technology research efforts. The staff supporting SPDF includes scientists and information technology experts.
MIT’s implementation of OpenGeoportal is called MIT Geoweb. It was collaboratively developed as an open source, federated web application to discover, preview, and retrieve geospatial data from different repositories. Several of the country's leading universities and a state agency have formed a partnership to make thousands of geospatial data layers available through a single, open source interface. The application also incorporates some new innovative search techniques. Partners include Tufts, Harvard, MIT, Princeton, MassGIS, Stanford and UC Berkeley. The single interface is skinnable and may have slight differences in appearance based on the institution hosting the application. You can search for GIS data held in the MIT Geodata Repository and other local colleges.
a collection of data at Agency for Healthcare Research and Quality (AHRQ) supporting research that helps people make more informed decisions and improves the quality of health care services. The portal contains U.S.Health Information Knowledgebase (USHIK) and Systematic Review Data Repository (SRDR) and other sources concerning cost, quality, accesibility and evaluation of healthcare and medical insurance.
The BGS is a data-rich organisation with over 400 datasets in its care; including environmental monitoring data, digital databases, physical collections (borehole core, rocks, minerals and fossils), records and archives. Our data is managed by the National Geoscience Data Centre. is the host website of the Center for Invasive Species and Ecosystem Health at the University of Georgia (Formerly: Bugwood Network). The Center aims to develop, consolidate and disseminate information and programmes focused on invasive species, forest health, natural resources and agricultural management through technology development, programmes implementation, training, applied research and public awareness at state, regional, national and international levels. The site gives details of its products (Bugwood Image Database; Early Detection and Distribution Mapping and Bugwoodwiki). Details of its projects, services and personnel are provided. Users can also access image databases on Forestry, Insects, IPM, Invasive Species, Forest Pests, weed and Bark Beetle.
The European Bioinformatics Institute (EBI) has a long-standing mission to collect, organise and make available databases for biomolecular science. It makes available a collection of databases along with tools to search, download and analyse their content. These databases include DNA and protein sequences and structures, genome annotation, gene expression information, molecular interactions and pathways. Connected to these are linking and descriptive data resources such as protein motifs, ontologies and many others. In many of these efforts, the EBI is a European node in global data-sharing agreements involving, for example, the USA and Japan.
The Index to Marine and Lacustrine Geological Samples is a tool to help scientists locate and obtain geologic material from sea floor and lakebed cores, grabs, and dredges archived by participating institutions around the world. Data and images related to the samples are prepared and contributed by the institutions for access via the IMLGS and long-term archive at NGDC. Before proposing research on any sample, please contact the curator for sample condition and availability. A consortium of Curators guides the IMLGS, maintained on behalf of the group by NGDC, since 1977.