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Found 1175 result(s)
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Using serial analysis of gene expression (SAGE) and microarrays, we are examining total mRNA populations in all developmental stages, both in whole worms and in specific cells and tissues. In addition, we are building promoter::GFP constructs to monitor gene expression in transgenic worms, focusing on C. elegans genes that have human orthologues. Also available are web-based PCR primer design tools, and access to information about our C. elegans Fosmid library.
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BRENDA is the main collection of enzyme functional data available to the scientific community worldwide. The enzymes are classified according to the Enzyme Commission list of enzymes. It is available free of charge for via the internet (http://www.brenda-enzymes.org/) and as an in-house database for commercial users (requests to our distributor Biobase). The enzymes are classified according to the Enzyme Commission list of enzymes. Some 5000 "different" enzymes are covered. Frequently enzymes with very different properties are included under the same EC number. BRENDA includes biochemical and molecular information on classification, nomenclature, reaction, specificity, functional parameters, occurrence, enzyme structure, application, engineering, stability, disease, isolation, and preparation. The database also provides additional information on ligands, which function as natural or in vitro substrates/products, inhibitors, activating compounds, cofactors, bound metals, and other attributes.
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CBS offers Comprehensive public databases of DNA- and protein sequences, macromolecular structure, g ene and protein expression levels, pathway organization and cell signalling, have been established to optimise scientific exploitation of the explosion of data within biology. Unlike many other groups in the field of biomolecular informatics, Center for Biological Sequence Analysis directs its research primarily towards topics related to the elucidation of the functional aspects of complex biological mechanisms. Among contemporary bioinformatics concerns are reliable computational interpretation of a wide range of experimental data, and the detailed understanding of the molecular apparatus behind cellular mechanisms of sequence information. By exploiting available experimental data and evidence in the design of algorithms, sequence correlations and other features of biological significance can be inferred. In addition to the computational research the center also has experimental efforts in gene expression analysis using DNA chips and data generation in relation to the physical and structural properties of DNA. In the last decade, the Center for Biological Sequence Analysis has produced a large number of computational methods, which are offered to others via WWW servers.
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The National Pollutant Release Inventory (NPRI) is Canada's legislated, publicly accessible inventory of pollutant releases (to air, water and land), disposals and transfers for recycling. It is a key resource for: identifying pollution prevention priorities; supporting the assessment and risk management of chemicals, and air quality modelling; helping develop targeted regulations for reducing releases of toxic substances and air pollutants; encouraging actions to reduce the release of pollutants into the environment; and improving public understanding. The NPRI comprises: Information reported by facilities and published by Environment and Climate Change Canada under the authority of Sections 46 – 50 of the Canadian Environmental Protection Act, 1999 (CEPA 1999); and Comprehensive emission summaries and trends for key air pollutants, based on facility-reported data and emission estimates for other sources such as motor vehicles, residential heating, forest fires and agriculture. For the latest reporting year, 7,708 facilities reported to the NPRI on more than 300 listed substances. Comprehensive air pollutant emission summaries and trends were compiled by Environment and Climate Change Canada for criteria air contaminants (the main pollutants contributing to smog, acid rain and/or poor air quality), selected heavy metals and persistent organic pollutants.
ScholarSphere is a secure repository service enabling the Penn State community to share its research and scholarly work with a worldwide audience. Faculty, staff, and students can use ScholarSphere to collect their work in one location and create a durable and citeable record of their papers, presentations, publications, data sets, or other scholarly creations. Through this service, Penn State researchers can also comply with grant-funding-agency requirements for sharing and managing research data.
Copernicus is a European system for monitoring the Earth. Copernicus consists of a complex set of systems which collect data from multiple sources: earth observation satellites and in situ sensors such as ground stations, airborne and sea-borne sensors. It processes these data and provides users with reliable and up-to-date information through a set of services related to environmental and security issues. The services address six thematic areas: land monitoring, marine monitoring, atmosphere monitoring, climate change, emergency management and security. The main users of Copernicus services are policymakers and public authorities who need the information to develop environmental legislation and policies or to take critical decisions in the event of an emergency, such as a natural disaster or a humanitarian crisis. Based on the Copernicus services and on the data collected through the Sentinels and the contributing missions , many value-added services can be tailored to specific public or commercial needs, resulting in new business opportunities. In fact, several economic studies have already demonstrated a huge potential for job creation, innovation and growth.
The CancerData site is an effort of the Medical Informatics and Knowledge Engineering team (MIKE for short) of Maastro Clinic, Maastricht, The Netherlands. Our activities in the field of medical image analysis and data modelling are visible in a number of projects we are running. CancerData is offering several datasets. They are grouped in collections and can be public or private. You can search for public datasets in the NBIA (National Biomedical Imaging Archive) image archives without logging in.
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CHAMP (CHAllenging Minisatellite Payload) is a German small satellite mission for geoscientific and atmospheric research and applications, managed by GFZ. With its highly precise, multifunctional and complementary payload elements (magnetometer, accelerometer, star sensor, GPS receiver, laser retro reflector, ion drift meter) and its orbit characteristics (near polar, low altitude, long duration) CHAMP will generate for the first time simultaneously highly precise gravity and magnetic field measurements over a 5 years period. This will allow to detect besides the spatial variations of both fields also their variability with time. The CHAMP mission had opened a new era in geopotential research and had become a significant contributor to the Decade of Geopotentials. In addition with the radio occultation measurements onboard the spacecraft and the infrastructure developed on ground, CHAMP had become a pilot mission for the pre-operational use of space-borne GPS observations for atmospheric and ionospheric research and applications in weather prediction and space weather monitoring. End of the mission of CHAMP was at September 19 2010, after ten years, two month and four days, after 58277 orbits.
Due to the changes at the individual IGS analysis centers during these years the resulting time series of global geodetic parameters are inhomogeneous and inconsistent. A geophysical interpretation of these long series and the realization of a high-accuracy global reference frame are therefore difficult and questionable. The GPS reprocessing project GPS-PDR (Potsdam Dresden Reprocessing), initiated by TU München and TU Dresden and continued by GFZ Potsdam and TU Dresden, provides selected products of a homogeneously reprocessed global GPS network such as GPS satellite orbits and Earth rotation parameters.
China Earthquake Data Center provides Seismic data, geomagnetic data, geoelectric data, terrain data and underground fluid change data. It is only open in the Seismological Bureau.
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PRISM is a digital archive of the university's intellectual output. Established and maintained by Libraries and Cultural Resources to manage, preserve and make available the academic works of faculty, students and research groups. The collection includes faculty publications, masters and doctoral theses, and research output from across Southern Alberta. PRISM is updated regularly, with new works added daily.
EMBL-EBI provides freely available data from life science experiments covering the full spectrum of molecular biology.The EBI Metagenomics service is an automated pipeline for the analysis and archiving of metagenomic data that aims to provide insights into the phylogenetic diversity as well as the functional and metabolic potential of a sample.
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TÁRKI Social Research Institute is an independent, employee-owned research organisation that specialises in policy research in the fields of social policy and the social consequences of economic policies. This includes related data-collection, archiving and statistical activities. We recently increased our involvement in the areas of strategic market research and health policy analysis. In addition, we regularly contribute to basic research, in the areas of social stratification and inequality, and to the methodology of empirical social research.
NED is a comprehensive database of multiwavelength data for extragalactic objects, providing a systematic, ongoing fusion of information integrated from hundreds of large sky surveys and tens of thousands of research publications. The contents and services span the entire observed spectrum from gamma rays through radio frequencies. As new observations are published, they are cross- identified or statistically associated with previous data and integrated into a unified database to simplify queries and retrieval. Seamless connectivity is also provided to data in NASA astrophysics mission archives (IRSA, HEASARC, MAST), to the astrophysics literature via ADS, and to other data centers around the world.
Chempound is a new generation repository architecture based on RDF, semantic dictionaries and linked data. It has been developed to hold any type of chemical object expressible in CML and is exemplified by crystallographic experiments and computational chemistry calculations. In both examples, the repository can hold >50k entries which can be searched by SPARQL endpoints and pre-indexing of key fields. The Chempound architecture is general and adaptable to other fields of data-rich science.
The Structure database provides three-dimensional structures of macromolecules for a variety of research purposes and allows the user to retrieve structures for specific molecule types as well as structures for genes and proteins of interest. Three main databases comprise Structure-The Molecular Modeling Database; Conserved Domains and Protein Classification; and the BioSystems Database. Structure also links to the PubChem databases to connect biological activity data to the macromolecular structures. Users can locate structural templates for proteins and interactively view structures and sequence data to closely examine sequence-structure relationships.
The Entrez Protein Clusters database contains annotation information, publications, structures and analysis tools for related protein sequences encoded by complete genomes. The data available in the Protein Clusters Database is generated from prokaryotic genomic studies and is intended to assist researchers studying micro-organism evolution as well as other biological sciences. Available genomes include plants and viruses as well as organelles and microbial genomes.
The DOE Data Explorer (DDE) is an information tool to help you locate DOE's collections of data and non-text information and, at the same time, retrieve individual datasets within some of those collections. It includes collection citations prepared by the Office of Scientific and Technical Information, as well as citations for individual datasets submitted from DOE Data Centers and other organizations.
The Database of Genomic Variants archive provides curated archiving and distribution of publicly available genomic structural variants. Direct submissions are accepted as well as published data. The DGVa is the primary supplier of data to the Database of Genomic Variants (DGV) (hosted by The Centre for Applied Genomics in Toronto, Canada).
TeachingWithData.org is a portal where faculty can find resources and ideas to reduce the challenges of bringing real data into post-secondary classes. It allows faculty to introduce and build students' quantitative reasoning abilities with readily available, user-friendly, data-driven teaching materials.
The IMSR is a searchable online database of mouse strains, stocks, and mutant ES cell lines available worldwide, including inbred, mutant, and genetically engineered strains. The goal of the IMSR is to assist the international scientific community in locating and obtaining mouse resources for research. Note that the data content found in the IMSR is as supplied by strain repository holders. For each strain or cell line listed in the IMSR, users can obtain information about: Where that resource is available (Repository Site); What state(s) the resource is available as (e.g. live, cryopreserved embryo or germplasm, ES cells); Links to descriptive information about a strain or ES cell line; Links to mutant alleles carried by a strain or ES cell line; Links for ordering a strain or ES cell line from a Repository; Links for contacting the Repository to send a query
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With ARS - Antimicrobial Resistance Surveillance in Germany - the infrastructure for a nationwide surveillance of antimicrobial resistance has been established, which covers both the inpatient medical care and the ambulatory care sector. This is intended to reliable data on the epidemiology of antimicrobial resistance in Germany and differential statements provided by structural features of the health care and by region are possible. ARS is designed as a laboratory-based surveillance system for continuous collection of resistance data from routine for the full range of clinically relevant bacterial pathogens. Project participants and thus data suppliers are laboratories that analyze samples of medical facilities and doctors' offices microbiologically.
The NCAA Student-Athlete Experiences Data Archive provides access to data about student athletes and will grow to include a handful of user-friendly data collections related to graduation rates; team-level Academic Progress Rates in Division I; and individual-level data on the experiences of current and former student-athletes from the NCAA's Growth, Opportunities, Aspirations and Learning of Students in college study (GOALS), and the Study of College Outcomes and Recent Experiences (SCORE). In the long run, the NCAA expects to follow this initial release with the publication of as much data as possible from its archives. The data is used by college presidents, athletic personnel, faculty, student-athlete groups, media members, and researchers in looking at issues related to intercollegiate athletics and higher education.