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Found 60 result(s)

Zentrale Biomaterialbank der Charité

Central Biomaterial Bank Charité

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Human biomaterial banks (short: biobanks) are collections of human body substances (i.e. blood, DNA, urine or tissue) connected with disease specific information. This allow for research of relations between deseases and underlying (molecular) modifications and paves the way for developing target-oriented therapies ("personalized medicine"). The biobank material arises from samples taken for therapeutical or diagnostic reasons or is extracted in the context of clinical trials. An approval for usage by the patient is always needed prior to any research activities.

Ozone Mapping and Profiler Suite

OMPS

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The Ozone Mapping and Profiler Suite measures the ozone layer in our upper atmosphere—tracking the status of global ozone distributions, including the ‘ozone hole.’ It also monitors ozone levels in the troposphere, the lowest layer of our atmosphere. OMPS extends out 40-year long record ozone layer measurements while also providing improved vertical resolution compared to previous operational instruments. Closer to the ground, OMPS’s measurements of harmful ozone improve air quality monitoring and when combined with cloud predictions; help to create the Ultraviolet Index, a guide to safe levels of sunlight exposure. OMPS has two sensors, both new designs, composed of three advanced hyperspectralimaging spectrometers.The three spectrometers: a downward-looking nadir mapper, nadir profiler and limb profiler. The entire OMPS suite currently fly on board the Suomi NPP spacecraft and are scheduled to fly on the JPSS-2 satellite mission. NASA will provide the OMPS-Limb profiler.

NIST Physical reference data

Physical reference data

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Physical Reference Data compiles physical data and biblographic sources: Physical constants, atomic spectroscopy data, molecular spectroscopic data, X-Ray and Gamma-Ray data, nuclear physics data etc.

Danish National Birth Cohort

DNBC

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Exposures in the period from conception to early childhood - including fetal growth, cell division, and organ functioning - may have long-lasting impact on health and disease susceptibility. To investigate these issues the Danish National Birth Cohort (Better health in generations) was established. A large cohort of pregnant women with long-term follow-up of the offspring was the obvious choice because many of the exposures of interest cannot be reconstructed with suffcient validity back in time. The study needed to be large, and the aim was to recruit 100,000 women early in pregnancy, and to continue follow-up for decades. Exposure information was collected by computer-assisted telephone interviews with the women twice during pregnancy and when their children were six and 18 months old. Participants were also asked to fill in a self-administered food frequency questionnaire in mid-pregnancy. Furthermore, a biological bank has been set up with blood taken from the mother twice during pregnancy and blood from theumbilical cord taken shortly after birth.

Diabetes Study of Northern California

DISTANCE

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<<<!!!<<< This repository is no longer available. >>>!!!>>> The Diabetes Study of Northern California (DISTANCE) conducts epidemiological and health services research in diabetes among a large, multiethnic cohort of patients in a large, integrated health care delivery system.

The Infrared Space Observatory data archive

ISO Data Archive

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The Infrared Space Observatory (ISO) is designed to provide detailed infrared properties of selected Galactic and extragalactic sources. The sensitivity of the telescopic system is about one thousand times superior to that of the Infrared Astronomical Satellite (IRAS), since the ISO telescope enables integration of infrared flux from a source for several hours. Density waves in the interstellar medium, its role in star formation, the giant planets, asteroids, and comets of the solar system are among the objects of investigation. ISO was operated as an observatory with the majority of its observing time being distributed to the general astronomical community. One of the consequences of this is that the data set is not homogeneous, as would be expected from a survey. The observational data underwent sophisticated data processing, including validation and accuracy analysis. In total, the ISO Data Archive contains about 30,000 standard observations, 120,000 parallel, serendipity and calibration observations and 17,000 engineering measurements. In addition to the observational data products, the archive also contains satellite data, documentation, data of historic aspects and externally derived products, for a total of more than 400 GBytes stored on magnetic disks. The ISO Data Archive is constantly being improved both in contents and functionality throughout the Active Archive Phase, ending in December 2006.

GISTEMP

GISS Surface Temperature Analysis

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Surface air temperature change is a primary measure of global climate change. The GISTEMP project started in the late 1970s to provide an estimate of the changing global surface air temperature which could be compared with the estimates obtained from climate models simulating the effect of changes in atmospheric carbon dioxide, volcanic aerosols, and solar irradiance. The continuing analysis updates global temperature change from the late 1800s to the present.

American Mineralogist Crystal Structure Database

AMCSD

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AMCSD is an interface to a crystal structure database that includes every structure published in the American Mineralogist, The Canadian Mineralogist, European Journal of Mineralogy and Physics and Chemistry of Minerals, as well as selected datasets from other journals. The database is maintained under the care of the Mineralogical Society of America and the Mineralogical Association of Canada, and financed by the National Science Foundation. You may search by a mineral of your choice, or choose a mineral from a complete list to help aid your research.

Health and Retirement Study

HRS

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The Health and Retirement Study (HRS) is a longitudinal panel study that surveys a representative sample of more than 26,000 Americans over the age of 50 every two years. The study has collected information about income, work, assets, pension plans, health insurance, disability, physical health and functioning, cognitive functioning, genetic information and health care expenditures.

eLibrary of Microbial Systematics and Genomics

eLMSG

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eLMSG (eLibrary of Microbial Systematics and Genomics) is a web microbial library that integrates not only taxonomic information, but also genomic information and phenotypic information (including morphology, physiology, biochemistry and enzymology). The taxonomic system of eLMSG is manually curated and composed of all validly and some effectively published taxa. For each taxon, the Latin name, taxon ID (NCBI taxonomy), etymology, rank, lineage, the dates of effective and/or valid publication, feature descriptions, nomenclature type and references for the proposal and emendations during the history of the taxon are presented. Besides these data, the species taxa contain information about 16S rRNA gene and/or genome sequences. All publicly available genome data of each type species including both type and non-type strains were collected, and if needed, re-annotated using the standardized analysis pipeline. Furthermore, pan-genomic data analyses were conducted for species with ≥5 genome sequences available. Finally, for all type species, taxonomically relevant phenotypic data were extracted and curated from literatures, which were further indexed into eLMSG as searchable and analyzable data records. Taken together, eLMSG is a comprehensive web platform for studying mi- crobial systematics and genomics, potentially useful for better understanding microbial taxonomy, natural evolutionary processes and ecological relationships.

Moderate Resolution Imaging Spectroradiometer

MODIS

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MODIS (or Moderate Resolution Imaging Spectroradiometer) is a key instrument aboard the Terra (originally known as EOS AM-1) and Aqua (originally known as EOS PM-1) satellites. Terra's orbit around the Earth is timed so that it passes from north to south across the equator in the morning, while Aqua passes south to north over the equator in the afternoon. Terra MODIS and Aqua MODIS are viewing the entire Earth's surface every 1 to 2 days, acquiring data in 36 spectral bands, or groups of wavelengths (see MODIS Technical Specifications). These data will improve our understanding of global dynamics and processes occurring on the land, in the oceans, and in the lower atmosphere. MODIS is playing a vital role in the development of validated, global, interactive Earth system models able to predict global change accurately enough to assist policy makers in making sound decisions concerning the protection of our environment.

Atmospheric Chemistry Experiment

ACE

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SCISAT, also known as the Atmospheric Chemistry Experiment (ACE), is a Canadian Space Agency small satellite mission for remote sensing of the Earth's atmosphere using solar occultation. The satellite was launched on 12 August 2003 and continues to function perfectly. The primary mission goal is to improve our understanding of the chemical and dynamical processes that control the distribution of ozone in the stratosphere and upper troposphere, particularly in the Arctic. The high precision and accuracy of solar occultation makes SCISAT useful for monitoring changes in atmospheric composition and the validation of other satellite instruments. The satellite carries two instruments. A high resolution (0.02 cm-¹) infrared Fourier transform spectrometer (FTS) operating from 2 to 13 microns (750-4400 cm-¹) is measuring the vertical distribution of trace gases, particles and temperature. This provides vertical profiles of atmospheric constituents including essentially all of the major species associated with ozone chemistry. Aerosols and clouds are monitored using the extinction of solar radiation at 1.02 and 0.525 microns as measured by two filtered imagers. The vertical resolution of the FTS is about 3-4 km from the cloud tops up to about 150 km. Peter Bernath of the University of Waterloo is the principal investigator. A dual optical spectrograph called MAESTRO (Measurement of Aerosol Extinction in the Stratosphere and Troposphere Retrieved by Occultation) covers the 400-1030 nm spectral region and measures primarily ozone, nitrogen dioxide and aerosol/cloud extinction. It has a vertical resolution of about 1-2 km. Tom McElroy of Environment and Climate Change Canada is the principal investigator. ACE data are freely available from the University of Waterloo website. SCISAT was designated an ESA Third Party Mission in 2005. ACE data are freely available through an ESA portal.

BioImages - Virtual Field-Guide

Virtual Field-Guide to UK Biodiversity

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This site offers an enormous collection of photographs of wild species and natural history objects. It covers most groups of organisms with the exception of birds and other vertebrates. The photographs are presented to illustrate biodiversity and as an aid to identification. The criterion for inclusion of a species is that it must have been, or might be expected to be, found in Britain or Ireland. BioImages follows the biological classification. Biota is a hierarchical system with species grouped in genera, genera in families, families in orders and so on up to kingdoms and superkingdoms. The datasets are linked to bioinfo: food webs and species interactions in the Biodiversity of UK and Ireland.

DrugBank

Open Data Drug & Drug Target Database

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The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. The latest release of DrugBank (version 5.1.1, released 2018-07-03) contains 11,881 drug entries including 2,526 approved small molecule drugs, 1,184 approved biotech (protein/peptide) drugs, 129 nutraceuticals and over 5,751 experimental drugs. Additionally, 5,132 non-redundant protein (i.e. drug target/enzyme/transporter/carrier) sequences are linked to these drug entries. Each DrugCard entry contains more than 200 data fields with half of the information being devoted to drug/chemical data and the other half devoted to drug target or protein data.

U.S. National Archives and Records Administration Dataverse

NARA Dataverse

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The National Archives and Records Administration (NARA) is the nation's record keeper. Of all documents and materials created in the course of business conducted by the United States Federal government, only 1%-3% are so important for legal or historical reasons that they are kept by us forever. Those valuable records are preserved and are available to you, whether you want to see if they contain clues about your family’s history, need to prove a veteran’s military service, or are researching an historical topic that interests you.

NIST Standard Reference Data

SRD

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NIST Data Gateway - provides easy access to many of the NIST scientific and technical databases. These databases cover a broad range of substances and properties from many different scientific disciplines. The Gateway includes links to free online NIST data systems as well as to information on NIST PC databases available for purchase.

Greenland Environmental Observatory at Summit Station

GEO Summit

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Greenland Environmental Observatory (GEOSummit) provides long term year round data on core atmospheric measurements, spatial phenomena, ice sheets, and the Arctic Environment. These data are available to researchers through the National Science Foundation's Science Coordination Office (SCO) which coordinates all research at GEOSummit. Currently there is not a central platform for multi-collaborator data distribution. For specific information related to research it is recommended to contact investigators directly.

Future of Families and Child Wellbeing Study

FFCWS

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The Fragile Families and Child Wellbeing Study changed its name to The Future of Families and Child Wellbeing Study (FFCWS). Note that all documentation issued prior to January 2023 contains the study’s former name. Any further reference to FFCWS should kindly observe this name change. The Fragile Families & Child Wellbeing Study is following a cohort of nearly 5,000 children born in large U.S. cities between 1998 and 2000 (roughly three-quarters of whom were born to unmarried parents). We refer to unmarried parents and their children as “fragile families” to underscore that they are families and that they are at greater risk of breaking up and living in poverty than more traditional families. The core Study was originally designed to primarily address four questions of great interest to researchers and policy makers: (1) What are the conditions and capabilities of unmarried parents, especially fathers?; (2) What is the nature of the relationships between unmarried parents?; (3) How do children born into these families fare?; and (4) How do policies and environmental conditions affect families and children?

Avon Longitudinal Study of Parents and Children

ALSPAC

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ALSPAC is a longitudinal birth cohort study which enrolled pregnant women who were resident in one of three Bristol-based health districts in the former County of Avon with an expected delivery date between 1st April 1991 and 31st December 1992. Around 14,000 pregnant women were initially recruited. Detailed information has been collected on these women, their partners and subsequent children using self-completion questionnaires, data extraction from medical notes, linkage to routine information systems and from hands-on research clinics. Additional cohorts of participants have since been enrolled in their own right including fathers, siblings, children of the children and grandparents of the children. Ethical approval for the study was obtained from the ALSPAC Ethics and Law Committee (IRB00003312) and Local Research Ethics.

FactSage

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FactSage is a fully integrated Canadian thermochemical database system which couples proven software with self-consistent critically assessed thermodynamic data. It currently contains data on over 5000 chemical substances as well as solution databases representing over 1000 non-ideal multicomponent solutions (oxides, salts, sulfides, alloys, aqueous, etc.). FactSage is available for use with Windows.

Virtual Fly Brain

VFB

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Virtual Fly Brain (VFB) - an interactive tool for neurobiologists to explore the detailed neuroanatomy, neuron connectivity and gene expression of the Drosophila melanogaster CNS.

Universal PBM Resource for Oligonucleotide Binding Evaluation

UniPROBE

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The UniPROBE (Universal PBM Resource for Oligonucleotide Binding Evaluation) database hosts data generated by universal protein binding microarray (PBM) technology on the in vitro DNA binding specificities of proteins. This initial release of the UniPROBE database provides a centralized resource for accessing comprehensive data on the preferences of proteins for all possible sequence variants ('words') of length k ('k-mers'), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In total, the database currently hosts DNA binding data for 406 nonredundant proteins from a diverse collection of organisms, including the prokaryote Vibrio harveyi, the eukaryotic malarial parasite Plasmodium falciparum, the parasitic Apicomplexan Cryptosporidium parvum, the yeast Saccharomyces cerevisiae, the worm Caenorhabditis elegans, mouse, and human. The database's web tools (on the right) include a text-based search, a function for assessing motif similarity between user-entered data and database PWMs, and a function for locating putative binding sites along user-entered nucleotide sequences

Portal to Los Alamos Opacity Codes

TOPS opacities

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Portal to Los Alamos Opacity Codes is your gateway to the set of opacity codes developed at the Los Alamos National Laboratory. The TOPS code has been developed to calculate multigroup opacities that can be written in a variety of formats for use in radiation transport codes. Arbitrary mixture of any elements for which OPLIB data exist is supported. Opacities of special mixtures that are important in astrophysical applications are also available as a separate option (Astrophysical opacities).

West of Scotland Twenty-07 Study

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The Twenty-07 Study was set up in 1986 in order to investigate the reasons for differences in health by socio-economic circumstances, gender, area of residence, age, ethnic group, and family type. 4510 people are being followed for 20 years. The initial wave of data collection took place in 1987/8, when respondents were aged 15, 35 and 55. The final wave of data collection took place in 2007/08 when respondents were aged 35, 55 and 75. In this way the Twenty-07 Study provides us with unique opportunities to investigate both the changes in people's lives over 20 years and how they affect their health, and the differences in people's experiences at the same ages 20 years apart, and how these have different effects on their health.

International HapMap Project

国际人类基因组单体型图计划

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<<<!!!<<< OFFLINE >>>!!!>>> A recent computer security audit has revealed security flaws in the legacy HapMap site that require NCBI to take it down immediately. We regret the inconvenience, but we are required to do this. That said, NCBI was planning to decommission this site in the near future anyway (although not quite so suddenly), as the 1,000 genomes (1KG) project has established itself as a research standard for population genetics and genomics. NCBI has observed a decline in usage of the HapMap dataset and website with its available resources over the past five years and it has come to the end of its useful life. The International HapMap Project is a multi-country effort to identify and catalog genetic similarities and differences in human beings. Using the information in the HapMap, researchers will be able to find genes that affect health, disease, and individual responses to medications and environmental factors. The Project is a collaboration among scientists and funding agencies from Japan, the United Kingdom, Canada, China, Nigeria, and the United States. All of the information generated by the Project will be released into the public domain. The goal of the International HapMap Project is to compare the genetic sequences of different individuals to identify chromosomal regions where genetic variants are shared. By making this information freely available, the Project will help biomedical researchers find genes involved in disease and responses to therapeutic drugs. In the initial phase of the Project, genetic data are being gathered from four populations with African, Asian, and European ancestry. Ongoing interactions with members of these populations are addressing potential ethical issues and providing valuable experience in conducting research with identified populations. Public and private organizations in six countries are participating in the International HapMap Project. Data generated by the Project can be downloaded with minimal constraints. The Project officially started with a meeting in October 2002 (https://www.genome.gov/10005336/) and is expected to take about three years.