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Found 4 result(s)
The Square Kilometre Array (SKA) is a radio telescope with around one million square metres of collecting area, designed to study the Universe with unprecedented speed and sensitivity. The SKA is not a single telescope, but a collection of various types of antennas, called an array, to be spread over long distances. The SKA will be used to answer fundamental questions of science and about the laws of nature, such as: how did the Universe, and the stars and galaxies contained in it, form and evolve? Was Einstein’s theory of relativity correct? What is the nature of ‘dark matter’ and ‘dark energy’? What is the origin of cosmic magnetism? Is there life somewhere else in the Universe?
ALSPAC is a longitudinal birth cohort study which enrolled pregnant women who were resident in one of three Bristol-based health districts in the former County of Avon with an expected delivery date between 1st April 1991 and 31st December 1992. Around 14,000 pregnant women were initially recruited. Detailed information has been collected on these women, their partners and subsequent children using self-completion questionnaires, data extraction from medical notes, linkage to routine information systems and from hands-on research clinics. Additional cohorts of participants have since been enrolled in their own right including fathers, siblings, children of the children and grandparents of the children. Ethical approval for the study was obtained from the ALSPAC Ethics and Law Committee (IRB00003312) and Local Research Ethics.
ChEMBL is a database of bioactive drug-like small molecules, it contains 2-D structures, calculated properties (e.g. logP, Molecular Weight, Lipinski Parameters, etc.) and abstracted bioactivities (e.g. binding constants, pharmacology and ADMET data). The data is abstracted and curated from the primary scientific literature, and cover a significant fraction of the SAR and discovery of modern drugs We attempt to normalise the bioactivities into a uniform set of end-points and units where possible, and also to tag the links between a molecular target and a published assay with a set of varying confidence levels. Additional data on clinical progress of compounds is being integrated into ChEMBL at the current time.