ChEMBL is a database of bioactive drug-like small molecules, it contains 2-D structures, calculated properties (e.g. logP, Molecular Weight, Lipinski Parameters, etc.) and abstracted bioactivities (e.g. binding constants, pharmacology and ADMET data).
The data is abstracted and curated from the primary scientific literature, and cover a significant fraction of the SAR and discovery of modern drugs
We attempt to normalise the bioactivities into a uniform set of end-points and units where possible, and also to tag the links between a molecular target and a published assay with a set of varying confidence levels. Additional data on clinical progress of compounds is being integrated into ChEMBL at the current time.
ChEMBL is a service of EMBL-EBI.
As part of the European Molecular Biology Laboratory (EMBL), the largest part of our funding comes from the governments of EMBL’s member states. The global importance of our work is reflected in the fact that we also attract significant funds from external sources, including some beyond Europe.