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The International Union of Basic and Clinical Pharmacology (IUPHAR) / British Pharmacological Society (BPS) Guide to PHARMACOLOGY is an expert-curated resource of ligand-activity-target relationships, the majority of which come from high-quality pharmacological and medicinal chemistry literature. It is intended as a “one-stop shop” portal to pharmacological information and its main aim is to provide a searchable database with quantitative information on drug targets and the prescription medicines and experimental drugs that act on them. In future versions we plan to add resources for education and training in pharmacological principles and techniques along with research guidelines and overviews of key topics. We hope that the IUPHAR/BPS Guide to PHARMACOLOGY (abbreviated as GtoPdb) will be useful for researchers and students in pharmacology and drug discovery and provide the general public with accurate information on the basic science underlying drug action.
The GWAS Catalog is an open access repository of all human genome wide association studies. It is considered the “go-to” resource for genetic evidence of associations between common genetic variation and diseases or phenotypes, is accessed by scientists, clinicians and other users worldwide, and is integrated with numerous other resources. Association data and metadata are identified and extracted from the scientific literature by expert data curators. Submissions of full genome wide summary data can be made directly by authors, either before or after journal publication.
As 3D and reality capture strategies for heritage documentation become more widespread and available, there has emerged a growing need to assist with guiding and facilitating accessibility to data, while maintaining scientific rigor, cultural and ethical sensitivity, discoverability, and archival standards. In response to these areas of need, The Open Heritage 3D Alliance (OHA) has developed as an advisory group governing the Open Heritage 3D initiative. This collaborative advisory group are among some of the earliest adopters of 3D heritage documentation technologies, and offer first-hand guidance for best practices in data management, sharing, and dissemination approaches for 3D cultural heritage projects. The founding members of the OHA, consist of experts and organizational leaders from CyArk, Historic Environment Scotland, and the University of South Florida Libraries, who together have significant repositories of legacy and on-going 3D research and documentation projects. These groups offer unique insight into not only the best practices for 3D data capture and sharing, but also have come together around concerns dealing with standards, formats, approach, ethics, and archive commitment. Together, the OHA has begun the journey to provide open access to cultural heritage 3D data, while maintaining integrity, security, and standards relating to discoverable dissemination. Together, the OHA will work to provide democratized access to primary heritage 3D data submitted from donors and organizations, and will help to facilitate an operation platform, archive, and organization of resources into the future.
EuPathDB (formerly ApiDB) is an integrated database covering the eukaryotic pathogens in the genera Acanthamoeba, Annacaliia, Babesia, Crithidia, Cryptosporidium, Edhazardia, Eimeria, Encephalitozoon, Endotrypanum, Entamoeba, Enterocytozoon, Giardia, Gregarina, Hamiltosporidium, Leishmania, Nematocida, Neospora, Nosema, Plasmodium, Theileria, Toxoplasma, Trichomonas, Trypanosoma and Vavraia, Vittaforma). While each of these groups is supported by a taxon-specific database built upon the same infrastructure, the EuPathDB portal offers an entry point to all of these resources, and the opportunity to leverage orthology for searches across genera.