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WikiPathways was established to facilitate the contribution and maintenance of pathway information by the biology community. WikiPathways is an open, collaborative platform dedicated to the curation of biological pathways. WikiPathways thus presents a new model for pathway databases that enhances and complements ongoing efforts, such as KEGG, Reactome and Pathway Commons. Building on the same MediaWiki software that powers Wikipedia, we added a custom graphical pathway editing tool and integrated databases covering major gene, protein, and small-molecule systems. The familiar web-based format of WikiPathways greatly reduces the barrier to participate in pathway curation. More importantly, the open, public approach of WikiPathways allows for broader participation by the entire community, ranging from students to senior experts in each field. This approach also shifts the bulk of peer review, editorial curation, and maintenance to the community.
The European Nucleotide Archive (ENA) captures and presents information relating to experimental workflows that are based around nucleotide sequencing. A typical workflow includes the isolation and preparation of material for sequencing, a run of a sequencing machine in which sequencing data are produced and a subsequent bioinformatic analysis pipeline. ENA records this information in a data model that covers input information (sample, experimental setup, machine configuration), output machine data (sequence traces, reads and quality scores) and interpreted information (assembly, mapping, functional annotation). Data arrive at ENA from a variety of sources. These include submissions of raw data, assembled sequences and annotation from small-scale sequencing efforts, data provision from the major European sequencing centres and routine and comprehensive exchange with our partners in the International Nucleotide Sequence Database Collaboration (INSDC). Provision of nucleotide sequence data to ENA or its INSDC partners has become a central and mandatory step in the dissemination of research findings to the scientific community. ENA works with publishers of scientific literature and funding bodies to ensure compliance with these principles and to provide optimal submission systems and data access tools that work seamlessly with the published literature.
The aim of the Freshwater Biodiversity Data Portal is to integrate and provide open and free access to freshwater biodiversity data from all possible sources. To this end, we offer tools and support for scientists interested in documenting/advertising their dataset in the metadatabase, in submitting or publishing their primary biodiversity data (i.e. species occurrence records) or having their dataset linked to the Freshwater Biodiversity Data Portal. This information portal serves as a data discovery tool, and allows scientists and managers to complement, integrate, and analyse distribution data to elucidate patterns in freshwater biodiversity. The Freshwater Biodiversity Data Portal was initiated under the EU FP7 BioFresh project and continued through the Freshwater Information Platform (http://www.freshwaterplatform.eu). To ensure the broad availability of biodiversity data and integration in the global GBIF index, we strongly encourages scientists to submit any primary biodiversity data published in a scientific paper to national nodes of GBIF or to thematic initiatives such as the Freshwater Biodiversity Data Portal.