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Found 10 result(s)

MorpheusML model repository

Morpheus model repository

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The public MorpheusML model repository collects, curates, documents and tests computational models for multi-scale and multicellular biological systems. Model must be encoded in the model description language MorpheusML. Subsections of the repository distinguish published models from contributed non-published and example models. New models are simulated in Morpheus or Artistoo independently from the authors and results are compared to published results. Successful reproduction is documented on the model's webpage. Models in this repository are included into the CI and test pipelines for each release of the model simulator Morpheus to check and guarantee reproducibility of results across future simulator updates. The model’s webpage provides a History-link to all past model versions and edits that are automatically tracked via Git. Each model is registered with a unique and persistent ID of the format M..... The model description page (incl. the biological context and key results of that model), the model’s XML file, the associated paper, and all further files (often simulation result videos) connected with that model can be retrieved via a persistent URL of the format https://identifiers.org/morpheus/M..... - for technical details on the citable ModelID please see https://registry.identifiers.org/registry/morpheus - for the model definition standard MorpheusML please see https://doi.org/10.25504/FAIRsharing.78b6a6 - for the model simulator Morpheus please see https://morpheus.gitlab.io - for the model simulator Artistoo please see https://artistoo.net/converter.html

ILC-CNR for CLARIN-IT repository

ILC4CLARIN

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ILC-CNR for CLARIN-IT repository is a library for linguistic data and tools. Including: Text Processing and Computational Philology; Natural Language Processing and Knowledge Extraction; Resources, Standards and Infrastructures; Computational Models of Language Usage. The studies carried out within each area are highly interdisciplinary and involve different professional skills and expertises that extend across the disciplines of Linguistics, Computational Linguistics, Computer Science and Bio-Engineering.

OpenWorm

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OpenWorm aims to build the first comprehensive computational model of the Caenorhabditis elegans (C. elegans), a microscopic roundworm. With only a thousand cells, it solves basic problems such as feeding, mate-finding and predator avoidance. Despite being extremely well studied in biology, this organism still eludes a deep, principled understanding of its biology. We are using a bottom-up approach, aimed at observing the worm behaviour emerge from a simulation of data derived from scientific experiments carried out over the past decade. To do so we are incorporating the data available in the scientific community into software models. We are engineering Geppetto and Sibernetic, open-source simulation platforms, to be able to run these different models in concert. We are also forging new collaborations with universities and research institutes to collect data that fill in the gaps All the code we produce in the OpenWorm project is Open Source and available on GitHub.

Datanator

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Datanator is an integrated database of genomic and biochemical data designed to help investigators find data about specific molecules and reactions in specific organisms and specific environments for meta-analyses and mechanistic models. Datanator currently includes metabolite concentrations, RNA modifications and half-lives, protein abundances and modifications, and reaction kinetics integrated from several databases and numerous publications. The Datanator website and REST API provide tools for extracting clouds of data about specific molecules and reactions in specific organisms and specific environments, as well as data about similar molecules and reactions in taxonomically similar organisms.

Comparative RNA Web

CRW

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The Comparative RNA Web (CRW) Site disseminates information about RNA structure and evolution that has been determined using comparative sequence analysis. We present both raw (sequences, structure models, metadata) and processed (analyses, evolution, accuracy) data, organized into four main sections.

Cancer Cell Line Encyclopedia

CCLE

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The Cancer Cell Line Encyclopedia project is a collaboration between the Broad Institute, and the Novartis Institutes for Biomedical Research and its Genomics Institute of the Novartis Research Foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models, to develop integrated computational analyses that link distinct pharmacologic vulnerabilities to genomic patterns and to translate cell line integrative genomics into cancer patient stratification. The CCLE provides public access to genomic data, analysis and visualization for about 1000 cell lines.

Digital Library for Earth System Education

DLESE

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<<<!!!<<< This repository is no longer available. >>>!!!>>>

BioSimulations

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BioSimulations is a web application for sharing and re-using biomodels, simulations, and visualizations of simulations results. BioSimulations supports a wide range of modeling frameworks (e.g., kinetic, constraint-based, and logical modeling), model formats (e.g., BNGL, CellML, SBML), and simulation tools (e.g., COPASI, libRoadRunner/tellurium, NFSim, VCell). BioSimulations aims to help researchers discover published models that might be useful for their research and quickly try them via a simple web-based interface.

datacommons@psu

Penn State Data Commons

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The datacommons@psu was developed in 2005 to provide a resource for data sharing, discovery, and archiving for the Penn State research and teaching community. Access to information is vital to the research, teaching, and outreach conducted at Penn State. The datacommons@psu serves as a data discovery tool, a data archive for research data created by PSU for projects funded by agencies like the National Science Foundation, as well as a portal to data, applications, and resources throughout the university. The datacommons@psu facilitates interdisciplinary cooperation and collaboration by connecting people and resources and by: Acquiring, storing, documenting, and providing discovery tools for Penn State based research data, final reports, instruments, models and applications. Highlighting existing resources developed or housed by Penn State. Supporting access to project/program partners via collaborative map or web services. Providing metadata development citation information, Digital Object Identifiers (DOIs) and links to related publications and project websites. Members of the Penn State research community and their affiliates can easily share and house their data through the datacommons@psu. The datacommons@psu will also develop metadata for your data and provide information to support your NSF, NIH, or other agency data management plan.

Virgo Millenium Database

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When published in 2005, the Millennium Run was the largest ever simulation of the formation of structure within the ΛCDM cosmology. It uses 10(10) particles to follow the dark matter distribution in a cubic region 500h(−1)Mpc on a side, and has a spatial resolution of 5h−1kpc. Application of simplified modelling techniques to the stored output of this calculation allows the formation and evolution of the ~10(7) galaxies more luminous than the Small Magellanic Cloud to be simulated for a variety of assumptions about the detailed physics involved. As part of the activities of the German Astrophysical Virtual Observatory we have created relational databases to store the detailed assembly histories both of all the haloes and subhaloes resolved by the simulation, and of all the galaxies that form within these structures for two independent models of the galaxy formation physics. We have implemented a Structured Query Language (SQL) server on these databases. This allows easy access to many properties of the galaxies and halos, as well as to the spatial and temporal relations between them. Information is output in table format compatible with standard Virtual Observatory tools. With this announcement (from 1/8/2006) we are making these structures fully accessible to all users. Interested scientists can learn SQL and test queries on a small, openly accessible version of the Millennium Run (with volume 1/512 that of the full simulation). They can then request accounts to run similar queries on the databases for the full simulations. In 2008 and 2012 the simulations were repeated.